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Background: Proteases of human pathogens are becoming increasingly important drug targets, hence it is necessary to understand their substrate specificity and to interpret this knowledge in practically useful ways. New methods are being developed that produce large amounts of cleavage information for individual proteases and some have been applied to extract cleavage rules from data. However, the
We tested whether the presence of plant roots would impair the uptake of ammonium ([Formula: see text]), glycine, and glutamate by microorganisms in a deciduous forest soil exposed to constant or variable moisture in a short-term (24-h) experiment. The uptake of (15)NH4 and dual labeled amino acids by the grass Festuca gigantea L. and soil microorganisms was determined in planted and unplanted soi
To determine the intrinsic and effective clothing evaporative resistances,both in the individual clothing, and in the nulti-layer clothing ensembles meant for winter season, a fabric sweating thermal manikin Walter was used. Based on the tests performed on the individual garments, two empirical equations were developed for the estimation of these resistances, useful either to clothing manufacturer
It is generally acknowledged that wetlands and barrier islands can reduce surge and waves. However, while a general qualitative understanding of these interactions is available in the scientific literature, quantification of these interactions is lacking and has previously been based on limited data of relatively poor quality. The overall aim of this study was to improve the understanding of the i
The purpose of the current work is the comparison of a phenomenological and a laminate-based model for rate-dependent switching in ferroelectric single crystals. To this end, the phenomenological model formulation of [1] is considered. In this model, the polarization vector is treated as an internal variable. The evolution of the polarization determines the remanent strain; dependence of energy st
We present a new high delay resolution method to detect ultra-wideband (UWB) scatterers when using frequency domain measurements. Our approach makes use of the impulse response envelope amplitudes and delays measured over a distance that is larger than the region of stationarity, and detects the 2D coordinates of the channel scatterers, assuming that only single-scattering (single-interaction) pro
The latest long-term plan for science and technology reflects China’s determination both to overcome growing domestic social and environmental problems through technology and to become a world leader in innovation. This latest fifteen-year plan presents no radical departure from earlier strategies and continues to define policymaking by Beijing’s strong belief that innovation can be “decreed” top-
Advances in scheduling theory have given designers of control systems greater flexibility over their choice of timing requirements. This could lead to systems becoming more responsive and more maintainable. However, experience has shown that engineers find it difficult to exploit these advantages due to the difficulty in determining the “real” timing requirements of systems and therefore the techn
We have successfully embedded a metal gate in-between two resonant tunneling double barrier heterostructures (RTD), thus realizing a three dimensional resonant tunneling transistor. The gate is placed 30 nm above and 100 below the two RTD's, respectively. The asymmetric gate allows for a unique control of the current-voltage characteristics, not only controlling the peak current but also the peak
A framework for operating procedure synthesis in batch processes was presented in part on of this paper. In this part, we present, iTOPS (intelligent tool for operating procedure synthesis), a knowledge based system for implementing the concepts outlined in the framework. iTOPS has been developed in Gensym's G2 expert system shell. The architecture of iTOPS, that consists of components that closel
The paper suggests a method for motion generating and stabilization with application to dynamical models for underactuated ships.
Intermittently administered PTH is known to increase bone mass in osteoporosis models. We studied its effects in bone repair and implant fixation, using histological and mechanical techniques in rats. In a bone chamber, PTH substantially increased the density of the new-formed bone, whereas there was only a minor effect on the pre-existing bone in the L5 vertebra or femur. Considering that PTH inc
