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INTRODUCTION: Amyloid-induced tauopathy drives clinical decline in Alzheimer's disease (AD). Because age and sex shape tau trajectories, defining patient-centered amyloid thresholds for tauopathy onset could facilitate pre-tauopathy AD identification and aid treatment decisions and prognosis. METHODS: By including two samples (Alzheimer's Disease Neuroimaging Initiative [ADNI, n = 301]; and 18F-AV
Public procurement has the potential to serve as a strategic driver for circular economy implementation and urban sustainability transitions. Purpose: This study explores how municipalities incorporate circular requirements into construction project procurement processes. The aim is to identify practical strategies that support circular implementation in construction projects. Methodology: U
Populärvetenskaplig sammanfattning: Kvävekoncentrationen i den gröna biomassan hos vegetation är involverad i många olika biokemiska processer i det terrestra ekosystemet. Till exempel så påverkar den fotosyntesen, förmultning och evaportanspirationen, för att nämna några. Därför är den också ofta en av grundparametrarna och drivkraften i olika ekosystem-modeller. Att mäta kvävehalten hos blad/barNitrogen in the green biomass of vegetation plays an important role in many biochemical processes in the terrestrial ecosystems, and often used as an input parameter to ecosystem models. It strongly influences photosynthetic rate, decomposition, and evaportanspiration, to name a few. Measuring nitrogen in field involves a lot of time and money, and it would be valuable if this part of the data col
Syftet med vår uppsats var att utreda behovet av multilingvistisk kundservice på den svenska marknaden samt att studera hur företag hanterar kunder med icke-svensk bakgrund. Vårt sekundära syfte vara att undersöka affärsmöjligheter för ett multilingvistiskt call center. Uppsatsens teoretiska ramverk består av kundbaserad teori, där teorier kring Customer Relation Management, kundservice, call cent
At a time of increasing environmental changes and geopolitical tensions, the need for collaboration in the Arctic is greater than ever. Top-down initiatives such as the Arctic Council have contributed to important increased collaboration and science diplomacy. Similarly, bottom-up initiatives have also played a major role in establishing diplomacy among researchers with spin-offs at government lev
With the advent of digitalization, the economy of the world is quickly changing itself and Indian Small and Medium Enterprises (SMEs) are the front runners. This study sheds light on how digital transformation is crucial to support the growth, competitiveness, and sustainability in the present business environment, and how digital transformation is important to the SMEs in India. To encourage SMEs
Household expenditure patterns in Ukraine were explored with a focus on clustering techniques to uncover socioeconomic insights and inform policy interventions. Using an officially published Household Income Survey dataset for 2021, the research applies advanced machine learning models, including k-means, DBSCAN, and PCA, to analyze spending habits and identify household profiles with distinct exp
The role of mutations have been subject to many controversies since the formation of the Modern Synthesis of evolution in the early 1940ties. Geneticists in the early half of the twentieth century tended to view mutations as a limiting factor in evolutionary change. In contrast, natural selection was largely viewed as a “sieve” whose main role was to sort out the unfit but which could not create a
Recent years have seen a sharply rising interest in the scientific area dedicated to the study of the use of Artificial Intelligence (AI) for Cognitive Behavioral Therapy (CBT) research and applications (AI4CBT for brevity). Yet, little is known about how this interest is realized and hence the overall status, prospects, and possible challenges of AI4CBT as a field (e.g. breadth of the field, key
INTRODUCTION: Biomarkers play a crucial role in understanding Alzheimer's disease (AD) pathogenesis and treatment effects. However, comparing biomarker measures without standardization and appreciating their magnitude relative to the disease can be challenging. METHODS: To address this issue, we propose the CentiMarker approach, similar to Centiloid, which provides a standardized scale between nor
This essay is the first systematic study of intramural executions in Sweden. It examines how intramural executions were introduced, and what effects it had on the publicity of executions. All intramural executions 1879‒1910 are studied. The essay presents three notable findings. First, that the aim of the introduction of intramural executions was not to exclude spectators per se, but to exclude wo
The exponential increase in medical waste production has increased the difficulty of waste management, resulting in higher medical waste dispersion into the environment. By employing a circular economy approach, it is possible to develop new materials by waste valorization. The employment of biodegradable and renewable agro-food, waste-derived materials may reduce the environmental impact caused b
Bakgrund: Den kurativa behandlingen för resektabla lokalt avancerade stadier av cancer i munhålan innefattar i regel en kombination av kirurgi och radioterapi (RT). Huruvida RT bör ges först och därefter följas av kirurgi, eller om tumören bör opereras bort först, följt av RT postoperativt, har dock inte studerats i någon större omfattning.Syfte: Denna avhandling undersöker olika aspekter av pre- Background: The curatively intended treatment for resectable locally advanced stages of oral cavity cancer (OCC) generally involves a combination of surgery and radiotherapy (RT). However, whether to apply RT first and then proceed with surgery, or to resect the cancer and subsequently administer RT, has not been extensively studied. Aims: This thesis examines various aspects of pre- versus postop
A diagonalisation procedure of the Foldy-Wouthuysen type is considered for the single-electron Dirac Hamiltonian as a basis for many-body applications. A modified procedure is suggested. In the diagonalisation procedure the Dirac equation is completely decoupled into two equations of the Pauli type. The expressions for positive- and negative-energy projection operators in the transformed basis are
Urbanity is primarily a term for experiencing the city, and urban experience is very much about memory. Since urban meaning, as perceptual meaning generally, is not predominantly made up of signs, other notions of meaning, such as extended cognition or exogram, introduced by cognitive science, affordance, as in Gibsonean psychology, and sedimentation, in the sense of Husserl, are tried out, and fo
Central to the exhibition are three seminal works: The Tempest Society (2017), The Circle Project (2023), and The Public Storyteller (2024). These works trace the legacy of the Mouvement des travailleurs arabes (MTA) and its theatre groups, Al Assifa and Al Halaka, highlighting their pioneering struggle for equal rights in 1970s France and their enduring relevance.Through storytelling, montage, an
Timber’s sustainability benefits make it an attractive construction material, but public concerns about fire safety remain a challenge. Many associate timber buildings with higher fire risks, particularly in taller structures, despite trusting regulations and professionals to ensure safety. This highlights a gap between public perception and technical knowledge. Designers have a professional respo
