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Ty hon har visat stor kärlek: En narrativ studie över Luk 7:36-50

The title, “for she loved much”, stems from Luke 7:47. The aim of this essay is to interpret Luke 7:36-50 using the method of narrative criticism, since the structure and rhythm of the episode is similar to the structure of a novel. The purpose is to inquire into the issues of forgiveness by analyzing whether the sinful woman of the city was forgiven before or after approaching Jesus during the di

Case study at Scania: How packaging options affect supply chain operations and costs

Background/introduction: Scania supply chain is responsible for packaging to protect parts during transportation from their suppliers around the world. For many years Scania has used returnable packaging for inbound logistics of automotive parts. Scania packaging can be divided into two groups; namely Standard packaging and Special packaging. Problem description: When introducing a newer solution

The transition between product development processes and its effects on cross-functional collaboration: A case study in the software development industry

This thesis examines how the transition from a linear product development process to a faster and iterative one affects the extent and quality of cross-functional collaboration within a company. It investigates both what changes such a transition entails, as well as how they may be explained. The setting of the study is the software development department of a multinational consumer electronics fi

Potentialen med smartare RPA-robotar: Innebär smartare RPA-robotar till följd av introduceringen av Machine Learning att dess roll och uppgifter i verksamhetsprocesser förändras.

Syftet med denna uppsats är att undersöka om de teoretiska fördelarna som Machine Learning kan ha på kapabiliteten hos AI-robotar har fått genomslag, och hur dessa fördelar kommer att påverka hur RPA-robotar placeras i verksamhetsprocesser i form av roll och uppgift. Genom intervjuer med branschexperter och sammanställning av teorier ser vi att introduceringen av ML i RPA-robotar kan innebära en u

On Credit Spreads: An Autoregressve Model Approach

This thesis proposes an autoregressive credit spread model to make long term simulations of credit spreads and credit indices in the Investment grade and High yield bond segments. Several models are tested, and the final spread model produces simulations with statistics consistent with historical data, even though the model itself is relatively parsimonious. A transition from spread to index is pro

WHAT DO THE BEST STRATEGIC THINKERS DO?

This thesis studies the cognitive elements in strategic thinking and aims to contribute to the assessment of a tool that is developed to measure this ability. Strategic thinking is an area in strategy research that has received little emphasis. There is a lack of understanding of the cognitive elements behind the ability to think strategically. Therefore, this research aims to gain a deeper insigh

Associations of hormone replacement therapy and oral contraceptives with risk of colorectal cancer defined by clinicopathological factors, beta-catenin alterations, expression of cyclin D1, p53, and microsatellite-instability

BACKGROUND: Postmenopausal hormone therapy (HRT) and oral contraceptive (OC) use have in several studies been reported to be associated with a decreased colorectal cancer (CRC) risk. However, data on the association between HRT and OC and risk of different clinicopathological and molecular subsets of CRC are lacking. The aim of this molecular pathological epidemiology study was therefore to evalua

Associations of anthropometric factors with KRAS and BRAF mutation status of primary colorectal cancer in men and women : a cohort study

Obesity is a well-established risk factor for colorectal cancer (CRC), and accumulating evidence suggests a differential influence of sex and anthropometric factors on the molecular carcinogenesis of the disease. The aim of the present study was to investigate the relationship between height, weight, bodyfat percentage, waist- and hip circumference, waist-hip ratio (WHR), body mass index (BMI) and

A variant in FTO shows association with melanoma risk not due to BMI

We report the results of an association study of melanoma that is based on the genome-wide imputation of the genotypes of 1,353 cases and 3,566 controls of European origin conducted by the GenoMEL consortium. This revealed an association between several SNPs in intron 8 of the FTO gene, including rs16953002, which replicated using 12,313 cases and 55,667 controls of European ancestry from Europe,

The Social Process of Escalation: A Promising Focus for Crisis Management Research

Background This study identifies a promising, new focus for the crisis management research in the health care domain. After reviewing the literature on health care crisis management, there seems to be a knowledge-gap regarding organisational change and adaption, especially when health care situations goes from normal, to non-normal, to pathological and further into a state of emergency or crisis.

Cyclin D1 expression in colorectal cancer is a favorable prognostic factor in men but not in women in a prospective, population-based cohort study.

BACKGROUND: Although colorectal cancer (CRC) is generally not considered to be a hormone-dependent malignancy, several sex-related differences in incidence, molecular characteristics and survival have been reported. Epidemiological studies have consistently shown that increased exposure to female sex hormones is associated with a lower risk of CRC in women, and cyclin D1, an important downstream e

High risk of tobacco-related cancers in CDKN2A mutation-positive melanoma families.

Germline mutations in the tumour suppressor gene CDKN2A occur in 5-20% of familial melanoma cases. A single founder mutation, p.Arg112dup, accounts for the majority of CDKN2A mutations in Swedish carriers. In a national program, carriers of p.Arg112dup mutation have been identified. The aim of this study was to assess cancer risks in p.Arg112dup carriers and their first degree relatives (FDRs) and

Does the Neighborhood Area of Residence Influence Non-Attendance in an Urban Mammography Screening Program? A Multilevel Study in a Swedish City.

The public health impact of population-based mammography screening programs depends on high participation rates. Thus, monitoring participation rates, as well as understanding and considering the factors influencing attendance, is important. With the goal to acquire information on the appropriate level of intervention for increasing screening participation our study aimed to (1) examine whether, o

Health-related lifestyle factors and mammography screening attendance in a Swedish cohort study.

To determine whether health-related lifestyle factors are associated with attendance at a population-based invitational mammography screening program in southern Sweden, data on health-related lifestyle factors (smoking, alcohol use, physical activity, BMI, diet, self-rated health, and stress) were obtained from the Malmö Diet and Cancer Study and linked to the Malmö mammography register (Sweden,

Alcohol consumption and the risk of renal cancers in the European prospective investigation into cancer and nutrition (EPIC)

Epidemiologic studies have reported that moderate alcohol consumption is inversely associated with the risk of renal cancer. However, there is no information available on the associations in renal cancer subsites. From 1992 through to 2010, 477,325 men and women in the European Prospective Investigation into Cancer and Nutrition cohort were followed for incident renal cancers (n=931). Baseline and

Dietary factors and in situ and invasive cervical cancer risk in the European prospective investigation into cancer and nutrition study

Some dietary factors could be involved as cofactors in cervical carcinogenesis, but evidence is inconclusive. There are no data about the effect of fruits and vegetables intake (F&V) on cervical cancer from cohort studies. We examined the association between the intake of F&V and selected nutrients and the incidence of carcinoma in situ (CIS) and invasive squamous cervical cancer (ISC) in

Simple guidelines for efficient referral of soft-tissue sarcomas: a population-based evaluation of adherence to guidelines and referral patterns.

BACKGROUND: Optimal treatment of soft-tissue sarcoma requires multidisciplinary management at a sarcoma center. However, these rare tumors are often misinterpreted as benign and many are inadequately treated outside a sarcoma center, with an increased risk of local recurrence that often requires further extensive surgical treatment. To improve referral and centralization of soft-tissue sarcoma man

Distinct gene expression profiles in ovarian cancer linked to Lynch syndrome.

Ovarian cancer linked to Lynch syndrome represents a rare subset that typically presents at young age as early-stage tumors with an overrepresentation of endometrioid and clear cell histologies. We investigated the molecular profiles of Lynch syndrome-associated and sporadic ovarian cancer with the aim to identify key discriminators and central tumorigenic mechanisms in hereditary ovarian cancer.

Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk

We conducted a genome-wide association study of male breast cancer comprising 823 cases and 2,795 controls of European ancestry, with validation in independent sample sets totaling 438 cases and 474 controls. A SNP in RAD51B at 14q24.1 was significantly associated with male breast cancer risk (P = 3.02 x 10(-13); odds ratio (OR) = 1.57). We also refine association at 16q12.1 to a SNP within TOX3 (