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Strategic Alterations of Posture are Delayed in Parkinson's Disease Patients during Deep Brain Stimulation

Parkinson's disease (PD) is characterized by rigidity, akinesia, postural instability and tremor. Deep brain stimulation (DBS) of the subthalamic nucleus (STN) reduces tremor but the effects on postural instability are inconsistent. Another component of postural control is the postural strategy, traditionally referred to as the ankle or hip strategy, which is determined by the coupling between the

Impact of insufficient sleep on dysregulated blood glucose control under standardised meal conditions

Aims/hypothesis: Sleep, diet and exercise are fundamental to metabolic homeostasis. In this secondary analysis of a repeated measures, nutritional intervention study, we tested whether an individual’s sleep quality, duration and timing impact glycaemic response to a breakfast meal the following morning. Methods: Healthy adults’ data (N = 953 [41% twins]) were analysed from the PREDICT dietary inte

Deep Brain Stimulation in the Subthalamic Nuclei Alters Postural Alignment and Adaptation in Parkinson’s Disease

Parkinson’s disease (PD) can produce postural abnormalities of the standing body position such as kyphosis. We investigated the effects of PD, deep brain stimulation (DBS) in the subthalamic nucleus (STN), vision and adaptation on body position in a well-defined group of patients with PD in quiet standing and during balance perturbations. Ten patients with PD and 25 young and 17 old control partic

IgE sensitization in a cohort of adolescents in southern Sweden and its relation to allergic symptoms

Background: There is a strong and consistent association between IgE sensitization and allergy, wheeze, eczema and food hypersensitivity. These conditions are also found in non-sensitized humans, and sensitization is found among individuals without allergy-related diseases. The aim of this study was to analyse the sensitization profile in a representative sample of the population, and to relate pa

Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling

Breast tumors of the basal-like, hormone receptor-negative subtype remain an unmet clinical challenge, as there is high rate of recurrence and poor survival in patients following treatment. Coevolution of the malignant mammary epithelium and its underlying stroma instigates cancer-associated fibroblasts (CAFs) to support most, if not all, hallmarks of cancer progression. Here we delineate a previo

Substituted polyfluoroaryl interactions with an arginine side chain in galectin-3 are governed by steric-, desolvation and electronic conjugation effects

In the β-d-galactopyranoside-binding protein galectin-3, synthetic inhibitors substituted at the 3-position of a thiodigalactoside core cause the formation of an aglycone binding pocket through the displacement of an arginine residue (Arg144) from its position in the apoprotein. To examine in detail the role of different molecular interactions in this pocket, we have synthesized a series of nine 3

Heritability of Atrial Fibrillation

Background - Previous reports have implicated multiple genetic loci associated with AF, but the contributions of genome-wide variation to AF susceptibility have not been quantified. Methods and Results - We assessed the contribution of genome-wide single-nucleotide polymorphism variation to AF risk (single-nucleotide polymorphism heritability, h2 g) using data from 120 286 unrelated individuals of

Stratification strength and light climate explain variation in chlorophyll a at the continental scale in a European multilake survey in a heatwave summer

To determine the drivers of phytoplankton biomass, we collected standardized morphometric, physical, and biological data in 230 lakes across the Mediterranean, Continental, and Boreal climatic zones of the European continent. Multilinear regression models tested on this snapshot of mostly eutrophic lakes (median total phosphorus [TP] = 0.06 and total nitrogen [TN] = 0.7 mg L−1), and its subsets (2

Spectral Analysis of Body Movement during Deep Brain Stimulation in Parkinson's Disease

Background: The characteristics of Parkinson's disease (PD) include postural instability and resting tremor. However, reductions of tremor amplitude do not always improve postural stability. Research question: What is the effect of deep brain stimulation (DBS) of the subthalamic nucleus (STN) on spectral analysis of body movement in patients with PD when tested without anti-PD medication? The effe

The ‘agrarian question’ in the rear view mirror – some personal reflections

After a long career in studying agricultural and rural development, in the following paper I take the opportunity to reflect on these issues in the rear view mirror. The advantage of this is of course that my biographical time span now covers a considerable historical one, starting with the apocalyptic alarms over the population bomb at the end of the 60s, especially in Asia, and the widespread fe

Implementation of national palliative care guidelines in Swedish acute care hospitals : A qualitative content analysis of stakeholders’ perceptions

In high-income countries a large proportion of all deaths occur in hospitals. A common way to translate knowledge into clinical practice is developing guidelines for different levels of health care organisations. During 2012, national clinical guidelines for palliative care were published in Sweden. Later, guidance for palliative care was issued by the National Board of Health and Welfare. The aim

Historiska stormhändelser som underlag vid riskanalys : Studie av översvämningarna 1872 och 1904 längs Skånes syd- och ostkust

Den 13 november 1872 inträffade en extrem översvämning i kustområdena kring Södra Östersjön. Högt vattenstånd i kombination med höga vågor ledde till att cirka 300 personer omkom och fler än 15 000 blev hemlösa. Utmed Skånes kust omkom minst 23 personer, över 100 bostadshus förstördes och hundratals kustfiskare förlorade sin inkomstkälla då båtar och fiskeredskap slogs sönder och drogs ut i havet.On November 13, 1872 an extreme flood occurred in the coastal areas surrounding the South Baltic Sea. An extreme storm surge in combination with high waves caused the death of about 300 people and more than 15,000 people lost their homes. Along the coast of Scania, southern Sweden, at least 23 people were killed and more than 100 houses were destroyed. Hundreds of fishermen lost their source of in

Emerging affinity-based proteomic technologies for large-scale plasma profiling in cardiovascular disease

Plasma biomarkers that reflect molecular states of the cardiovascular system are central for clinical decision making. Routinely used plasma biomarkers include troponins, natriuretic peptides, and lipoprotein particles, yet interrogate only a modest subset of pathways relevant to cardiovascular disease. Systematic profiling of a larger portion of circulating plasma proteins (the plasma proteome) w

Investeringsrådgivning - bankernas skyldigheter

Finansmarknaden genomgick stora förändringar innan 2000-talet och placeringsrådgivning kom att spela en allt viktigare roll. Tidigare hade det inte funnits lagstiftning på området, vilket man nu införde. Först kom Lag (2003:862) om finansiell rådgivning till konsumenter (FRL), därefter utfärdades ett EG-direktiv. Direktivet införlivades i svensk rätt genom Lag (2007:528) om värdepappersmarknaden (The Financial Market went through significant changes before the 2000’s and investments advisory played an increasingly important role. Earlier there had not been any legislation on the subject which there is now. The first legislation was the act of financial advisory and after that the Markets in Financial Instruments Directive, MiFID came from the EU. MiFID was implemented into Swedish law thro

Does co-development with ai assistants lead to more maintainable code? : A registered report

[Background/Context] AI assistants like GitHub Copilot are transforming software engineering; several studies have highlighted productivity improvements. However, their impact on code quality, particularly in terms of maintainability, requires further investigation. [Objective/Aim] This study aims to examine the influence of AI assistants on software maintainability, specifically assessing how the

Will the electrical grid sustain the change towards an electrified freight truck fleet?

Med en elektrifiering av tunga lastbilar kommer elbehovet att ̈oka kraftigt och elnätet ̈ar inte förberedd p ̊a utmaningen. Det rader kapacitetsbrist i nätet och det behöver utredas hur den kan undvikas. Transportsektorn star infor stora förändringar för att minska sitt klimatavtyck. Elnätet ̈ar en kritisk infrastruktur för att möjliggöra denna omställning. Förutom att bygga ut finns det m ̈ojlighThe transport sector is facing major challenges to reduce the greenhouse gas emissions. The electrification of the freight fleet, which is an important step towards emission reduction, will result in capacity challenges in the grid. The aim of this thesis is to evaluate how the existing grid is affected by the electrification of heavy trucks and what solutions or reinforcements needs to be impleme

Nämndemannasystemet - en undersökning om legal och demokratisk förutsebarhet

Nämndemän har varit med och påverkat dömandet i våra domstolar i mer än 800 år. Deras inflytande har varierat en del under århundradena men aldrig har de haft så stor domsmakt som idag. I tingsrätten dömer vanligtvis fyra domare varav en är juridiskt utbildad (ordföranden) och tre är nämndemän. I röstningsförfarandet väger allas röst lika tungt. Det är kommunfullmäktige som väljer vilka som ska siLay judges have been able to influence the judgments in our courts for more than 800 years. Their influence has varied somewhat over the centuries but never have they had such great judicial power as today. In District Courts there are usually four judges, one of whom is legally trained and three who are lay judges. In the voting process every judge has the same power. The city council decides who

Rapport oresundsregionen lu

2 ÖRESUNDSREGIONEN SOM PRIORITERING PÅ LUNDS UNIVERSITET? FÖRFATTARE Christer Eldh, universitetslektor vid Institutionen för service management och tjänstevetenskap, Lunds universitet Elin Fredriksson, studentmedarbetare vid Centrum för Öresundsstudier, Lunds universitet Markus Idvall, föreståndare för Centrum för Öresundsstudier, Lunds universitet, 2018–2019 Innehåll INLEDNING 3 METOD OCH MATERIA

https://www.cors.lu.se/sites/cors.lu.se/files/rapport_oresundsregionen_lu.pdf - 2026-05-30

SKÅE07 Dramaturgens Yrkespraktik 2

SKÅE07 Dramaturgens yrkespraktik 2 Lunds universitet Konstnärliga fakulteten SKÅE07, Dramaturgens yrkespraktik 2, 30 högskolepoäng The Professional Practice of the Dramaturge 2, 30 credits Grundnivå / First Cycle Fastställande Kursplanen är fastställd av Institutionsstyrelsen vid Teaterhögskolan i Malmö 2023-03- 22 att gälla från och med 2024-01-15, vårterminen 2024. Allmänna uppgifter Kursen är e

https://www.thm.lu.se/sites/thm.lu.se/files/2023-04/SK%C3%85E07%20Dramaturgens%20yrkespraktik%202.pdf - 2026-05-30