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Ontological analysis facilitates microarray data interpretation. We describe new ontological analysis methods which, unlike existing approaches, are threshold-free and statistically powerful. We perform extensive evaluations and introduce a new concept, detection spectra, to characterize methods. We show that different ontological analysis methods exhibit distinct detection spectra, and that it is
Timely regulation of phosphatidylinositol-3,4-bisphosphate [PI(3,4)P2] and phosphatidylinositol-3,4,5-trisphosphate [PI(3,4,5)P3] abundance in cells is essential for the control of cellular homeostasis. The concentrations of these lipids are low in quiescent cells but rapidly and transiently increase following growth factor receptor (GFR) stimulation, which triggers cellular metabolic changes, pro
The International Aid Transparency Initiative (IATI) is an agreement establishing a common standard for the reporting of information about aid and development funding. Signatories include nations, intergovernmental organizations (IGOs), nongovernmental organizations (NGOs), civil society organizations (CSOs) and private foundations, which together account for approximately 80 per cent of all inter
Hydrogenolysis of biodiesel-derived glycerol to value-added chemicals has emerged as an innovative approach to biowaste valorization for a more sustainable society. In the present work, Ru catalysts on Al2O3/AlF3 supports with different AlF3 content were prepared by the aqueous incipient wetness method and tested in the reaction of glycerol hydrogenolysis for the first time. The prepared catalysts
This article presents the addition of camber to a previously published semi-empirical tyre model by the same authors. The model combines empirical models for pure braking, cornering and cambering with a model for simultaneous braking, cornering and cambering. It is based on brush-model tyre mechanics and aims to offer an easy-to-use accurate model for vehicle-handling simulations. The proposed mod
Materials having bimodal grain structures are known for the good balance of strength and ductility. However, methods for their fabrication often lack the control of such structure characteristics. In this work, the principles of "harmonic" structure fabrication allowing to control both topology and scale of the bimodal structure heterogeneity have been concisely formulated. The feasibility to form
After the economic recession suffered during the eighties decade, the population under poverty conditions has increased dramatically. With the purpose of amend the situation; President Carlos Salinas has established the biggest anti-poverty program in Mexican history, the Programa Nacional de Solidaridad (PRONASOL). The following three administrations continued the implementation of these policies
In 1997 the Ugandan government introduced a reform program with the ambition to implement universal primary education. The abolition of tuition fees would ideally guarantee access to the public service delivery system as far as primary education is concerned and help to integrate underprivileged groups with the rest of the diverse society. The launch of universal primary education in Uganda implie
Issue of study: The plastic injection moulding industry has become highly competitive in terms of lead times and pricing, following an increase in low-cost manufacturing from Asia, as a part of the full supply chain. To remain competitive, mould tool manufacturers are looking to complement new tool manufacturing with local after-sales services in countries where their mould tools are being used. U
This report describes the methodology for performing a quantitative risk analysis for a unidirectional road tunnel. By using representative accident scenarios, a basic queue model and performing an evacuation analysis the amount of casualties for each scenario can be estimated. By using the described methodology it gives the decision-makers a good idea of the risk level in the tunnel. The results
Sammanfattning Digitala övervakningskameror har tidigare använts inom fenologisk forskning för att kunna mäta grönskan i trädkronor. Man har under en längre tid kunnat koppla lövträdets årscykel till klimatförändringar och på så sätt haft ett starkt incitament att studera sambandet. I denna uppsats utforskas möjligheten att applicera metoden med digitalkameror på ett nyligen kalhugget område för aAbstract The use of inexpensive digital cameras in phenological research has been acclaimed since results in previous research have shown that they are reliable and precise in measuring greenness of vegetation. The work of this thesis aims to broaden the applicability by studying how well the method performs when measuring the regrowth of a clear-cut area. This is needed to complement existing res
As the spread of the internet continues, more people than ever search for medical information online when in need of health advice. Color is a prominent part of website aesthetics, and has been shown in the literature to have both positive and negative psychological effects. A total of 120 participants took part in the present study where the effect of the colors grey, blue, orange and red was tes
Popular science summary: Potential Distribution for the Endangered Asian Wild Ass Over the past century, large mammals have been globally under increasing pressure of humanized landscapes. Since extirpations of large herbivores are likely to have complicated consequences for the entire ecosystem, their conservation is a priority. With almost 81% threatened species, Perissodactyla (odd-toad ungu
