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Background: Sleep deprivation among adolescents is a major public health issue. Although previous studies have described their sleep habits and the consequences thereof, the voices of adolescents themselves are rarely heard. The aim of this study was to investigate adolescents’ experiences regarding what they perceived as facilitators and barriers for a good night’s sleep. Methods: A qualitative f
The Myc oncoprotein is tightly regulated at multiple levels including ubiquitin-mediated protein turnover. We recently demonstrated that inhibition of Cdk2-mediated phosphorylation of Myc at Ser-62 pharmacologically or through interferon (IFN)-γ-induced expression of p27Kip1 (p27) repressed Myc's activity to suppress cellular senescence and differentiation. In this study we identified an additiona
De senaste teknologiska framstegen har lett till skapandet av högspecialiserade system inom olika industrier, vilket möjliggör uppgifter som tidigare varit otänkbara. I takt med att den globala efterfrågan på hållbara och effektiva energilösningar ökar, har behovet av innovation inom teknik aldrig varit större. Dessa framsteg representerar transformativa förändringar som omformar hela sektorer. FrRecent technological advancements have led to the creation of highly specialized systems across various industries, enabling tasks that were once beyond imagination. As the global demand for sustainable and efficient energy solutions grows, the urgency for innovation in technology has never been greater. These advancements are not simply incremental but represent transformative changes that are re
We prove an operator identity for the shift operator in the scale of standard weighted Bergman spaces in the unit disc. This operator identity is then applied in the context of functional calculus for the shift operator and a characterization of harmonic symbol Bergman space Toeplitz operators is obtained generalizing an earlier result by Louhichi and Olofsson. Duality arguments lead to operator i
Video available at: http://www.youtube.com/watch?v=2P8JTEygNcU What are the differences and similarities between the playing techniques of the siku and the quena in Peru and Bolivia, and in addition, the ways these techniques are taught? This is an investigation into the differences and similarities concerning playing techniques of the quena (Andes end-blown flute) and the siku (Andes panpipes) b
After the Cold War the nature and character of international conflict has changed dramatically, from traditional inter-state conflicts to protracted social conflicts. This constitutes a major challenge to contemporary peacebuilders, foremost the UN, but the expanding size and number of peacekeeping missions are threatening to erode UN resources. Peacebuilding scholars have different views on what
The aim of this collaboration, between the division of Thermal Power Engineering and Lunds Energi AB, is to investigate the possibilities of training artificial neural networks (ANNs) with power plant operational data. For this purpose operational data from Lunds Energi's gas turbine GT10B with heat recovery unit (HRU) will be used. Furthermore a model with user interface is created to dem
The purpose of this thesis was to examine the EC Commission's role and policy in the EC control of state aid to companies that risk going out of business. The thesis explores the Commission's role in relation to the Member States as well as to the Community courts. It also examines the Commission's policy towards such aid in order to establish whether the Commission is coherent in its
This thesis has been written as a part of the degree project course in the Master’s program “Sustainable Business Leadership” at the School of Economics and Management, Lund University. The course was based on the methodology of action learning and self-managed learning. The students were all assigned to an in-company project, having a role as consultants. This project constituted the main part of
Mitigating climate change will require large-scale changes to energy systems. Two examples are increased use of renewable energy resources and electrification of the transport sector. These changes increase demand for metals. This chapter looks into which metals are used in renewable energy technologies and why, how much is required to transition the global energy system and which countries hold t
All over the world there is a shortage of adequate, affordable housing that enables social integration and sustainability. Many individuals and households have access to housing but live in different kinds of involuntary isolation with respect to age, gender, income, culture and ethnic background. There is a lack of housing forms that can contribute to solving these societal challenges through dif
An analytical method is developed for ultrasensitive detection of citrinin using double isothermal amplification and CRISPR-Cas12a. Gold nanoparticles (AuNPs) modified with antigen and thiol-terminated, single-strand DNA (ssDNA) are used as a probe. The antigen-modified AuNPs compete with citrinin to bind to magnetic beads coated with an anticitrinin antibody. After a simple magnetic separation, t
Understanding the inherited nature of how biological processes dynamically change over time and exhibit intra- and inter-individual variability, due to the different responses to environmental stimuli and when interacting with other processes, has been a major focus of systems biology. The rise of single-cell fluorescent microscopy has enabled the study of those phenomena. The analysis of single-c
Glaucoma is a leading cause of blindness. Current glaucoma medications work by lowering intraocular pressure (IOP), a risk factor for glaucoma, but most treatments do not directly target the pathological changes leading to increased IOP, which can manifest as medication resistance as disease progresses. To identify physiological modulators of IOP, we performed genome- and exome-wide association an
