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B lymphocyte development is a complex biological process critically dependent on the transcription factor early B cell factor (EBF). To deepen understanding of the roles for EBF in this process, we have used Pearson correlation analysis to evaluate microarray data from a set of mouse B lymphoid cell lines representing different stages of development. Comparing the expression pattern of EBF to that

In this article a method to estimate the mean upcrossing intensity, mu(u), of a stochastic process is proposed. It is assumed that the stochastic process is a sum of a Gaussian process and a second-order correction term. The method is based on the two-dimensional Saddlepoint approximation. The accuracy of the method is tested on processes having analytical solutions for mu(u). Numerical examples a

Chronic myeloid leukemias and 5% to 20% of acute lymphoid leukemias are characterized by the Philadelphia chromosome, a reciprocal chromosomal translocation, t(9;22)(q34;q11), generating BCR-ABL and ABL-BCR fusion genes. Cytogenetic studies have recently shown a preferential involvement of the paternally derived chromosome 9 and the maternally derived chromosome 22 in this translocation, indicatin

PURPOSE: To assess the visual results, retinal detachment (RD) rate, incidence of glaucoma, and intraocular lens (IOL) placement after vitrectomy for removal of retained lens fragments in the vitreous after phacoemulsification. SETTING: Department of Ophthalmology, University Hospital of Lund, Lund, Sweden. METHODS: This retrospective noncomparative interventional case series included all cases of

Different theories have been proposed regarding the nature of the mental representations formed as a result of implicit learning of sequential regularities. Some theories postulate abstract surface-independent representations, while other theories postulate stimulus-specific representations. This article reports three experiments investigating the development of abstract representations in artific

In vitro amplification of nucleic acids using the polymerase chain reaction (PCR) has become, since its discovery in the 1980s, a powerful diagnostic tool for the analysis of microbial infections as well as for the analysis of microorganisms in food samples. However, despite its potential, PCR has neither gained wide acceptance in routine diagnostics nor been widely incorporated in standardized me

Purpose – This paper aims to contribute to the development and understanding of corporate social responsibility (CSR) by discussing two interrelated characteristics of current literature: a tendency in discourses to portray CSR as equal to the societal activities displayed by and demanded from large, multinational firms; and an increasing focus on and description of “small firm CSR” in research. T

In this paper we extend the eliminant construction of Burchnall and Chaundy for commuting differential operators in the Heisenberg algebra to the q-deformed Heisenberg algebra and show that it again provides annihilating curves for commuting elements, provided q satisfies a natural condition. As a side result we obtain estimates on the dimensions of the eigenspaces of elements of this algebra in i

A theoretical model has been developed that describes ultrafiltration of nonionic surfactants. The model takes into account the fact that surfactants start to aggregate and form micelles at the critical micelle concentration, The model can be used to predict the performance of the membrane if the transport properties inside and at the membrane surface as well as the surfactant association behavior

Popular Abstract in Swedish Hjärt- och kärlsjukdomar som till exempel åderförkalkning utgör en av världens vanligaste dödsorsaker. I den här avhandlingen har vi utvecklat olika metoder som med hjälp av bildanalys ger värdefull information om kärlväggen i syfte att förbättra kunskapen om artärer och framförallt åderförkalkning. I avhandlingen presenteras fem olika metoder som alla är baserade på biAtherosclerosis is one of the major causes of death in the world. It is an inflammatory disease in the arteries which causes a gradual increase in arterial wall thickness and stiffness. Eventually a plaque could be formed, protruding into the artery and partially occluding the blood flow. Rupture of such a plaque could cause cardiac infarction or stroke. This dissertation revolves around finding b

Derivatives, or Jacobians, are commonly required by numerical algorithms. Access to accurate Jacobians often improves the performance and robustness of algorithms, and in addition, efficient implementation of Jacobian computations can reduce the over-all execution time. In this paper, we present methods for computing Jacobians in the context of the Functional Mock-up Interface (FMI), and Modelica.

A consortium of interested parties has conducted an experimental characterization of two Tau parallel kinematic machines which were built as a part of the EU-funded project, SMErobot1. Characteristics such as machine stiffness, work envelope, repeatability and accuracy were considered. This paper will present a brief history of the Tau parallel machine, the results of this testing and some comment

We present a polynomial time method for identifying the maximal set in excess demand at a given payoff vector. This set can be used in "large" partnership formation problems to identify the minimum element in the set of individually rational payoff vectors at which there is no overdemanded set of agents. This minimum element corresponds to the minimum Walrasian equilibrium price vector in a specia

Friction may be a major obstacle for stability and control performance. Based on a nominal control law, which stabilizes a nonlinear dynamical system to an equilibrium or to a desired limit cycle motion and which is derived without taking the friction disturbance into account, a method for compensating the impact of the friction is presented and stability analysis for the closed loop system is pre