Search results

Dipeptidyl peptidase (DPP)-4 inhibition is a glucose-lowering treatment for type 2 diabetes. The classical mechanism for DPP-4 inhibitors is that they inhibit DPP-4 activity in peripheral plasma, which prevents the inactivation of the incretin hormone glucagon-like peptide (GLP)-1 in the peripheral circulation. This in turn increases circulating intact GLP-1, which results in stimulated insulin se

Generation of high-purity human ventral midbrain dopaminergic progenitors for in vitro maturation and intracerebral transplantation © 2 01 7 N at u re A m er ic a, In c. , p ar t o f S p ri n g er N at u re . A ll ri g h ts r es er ve d . © 2 01 7 N at u re A m er ic a, In c. , p ar t o f S p ri n g er N at u re . A ll ri g h ts r es er ve d . © 2017 Macmillan Publishers Limited, part of Springer

https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/publication_in_nature_protocols.pdf - 2026-07-25

Generation of high-purity human ventral midbrain dopaminergic progenitors for in vitro maturation and intracerebral transplantation © 2 01 7 N at u re A m er ic a, In c. , p ar t o f S p ri n g er N at u re . A ll ri g h ts r es er ve d . © 2 01 7 N at u re A m er ic a, In c. , p ar t o f S p ri n g er N at u re . A ll ri g h ts r es er ve d . © 2017 Macmillan Publishers Limited, part of Springer

https://www.wnc.lu.se/sites/wnc.lu.se/files/nprot.2017.078.pdf - 2026-07-25

Prehistoric population structure associated with the transition to an agricultural lifestyle in Europe remains a contentious idea. Population-genomic data from 11 Scandinavian Stone Age human remains suggest that hunter-gatherers had lower genetic diversity than that of farmers. Despite their close geographical proximity, the genetic differentiation between the two Stone Age groups was greater tha

Polyurethanes and polycarbonates are widely used in a variety of applications including engineering, optical devices, and high-performance adhesives and coatings, etc., and are expected to find use also in the biomedical field owing to their biocompatibility and low toxicity. However, these polymers are currently produced using hazardous phosgene and isocyanates, which are derived from the reactio

A common application of nanometer-sized gold particles is as seed particles for growth of semiconductor nanowires, which are believed to act as highly promising building blocks in future electronic devices. In a majority of the reports of successful nanowire growth, gold has been the seed particle material of choice. In this review article we identify the different types of gold particles used to

Objective To develop evidence-based recommendations for the diagnosis of knee osteoarthritis (OA). Methods The multidisciplinary guideline development group, representing 12 European countries, generated 10 key propositions regarding diagnosis using a Delphi consensus approach. For each recommendation, research evidence was searched systematically. Whenever possible, the sensitivity, specificity a

The Tile hadronic calorimeter of the ATLAS detector has undergone extensive testing in the experimental hall since its installation in late 2005. The readout, control and calibration systems have been fully operational since 2007 and the detector has successfully collected data from the LHC single beams in 2008 and first collisions in 2009. This paper gives an overview of the Tile Calorimeter perf

The MAX IV pro-injector will have one thermionic and one photocathode S-band RF gun, where the former will be used for ring injections. During ring injections, the bunches leaving the pre-injector have a structure that consists of ten 10 ns bunch trains, each containing three bunches. A chopper system consisting of two striplines and an adjustable aperture is used, where the desired bunch structur

Objectives: To develop European League Against Rheumatism (EULAR) recommendations for the management of large vessel vasculitis. Methods: An expert group (10 rheumatologists, 3 nephrologists, 2 immunolgists, 2 internists representing 8 European countries and the USA, a clinical epidemiologist and a representative from a drug regulatory agency) identified 10 topics for a systematic literature searc

The aim of this study is to gain an understanding of the potential relationship between populism and a population’s search for security and belonging. Furthermore, how this is expressed through the rhetoric and policies of a country’s leader, Recep Tayyip Erdoğan in Turkey, and Viktor Orbán in Hungary, this is examined through conducting a qualitative content analysis. Here I use newspaper article

In this master thesis we consider some phenomenological aspects of two-Higgs-doublet models, both elementary and composite ones. The emphasis is on calculating and understanding first order phase transitions in such models, constrained to be in agreement with existing collider data on the Higgs sector. We also consider the contribution to the gravitational wave background of the universe that woul

Open data is broadly expected to generate innovation and economic value for both the public and private sector. Though the diffusion of open data has kept a fast pace, knowledge of visualisation and points of access of open data remains low. Moreover, literature of the private-sector application of open data is still scarce. The first objective of this thesis is to increase the knowledge about the

LDMX is a fixed target experiment designed to search for light dark matter. The experiment will search for dark matter signatures using missing momentum and energy in events with electrons scattering in the target. Part of the experimental setup in this search is a high granularity electromagnetic calorimeter to accurately measure the energies of recoil electrons. In this thesis artificial neura

Det finns ett växande behov av miljövänliga sätt att transportera sig och därför har elcykeln slagit stort i Sverige. Elcykeln används ofta som transportmedel till och från jobbet men har potential att användas i andra sammanhang också. Miljöpåverkan orsakad av transport under semesterresor har uppmärksammats på senare tid. Samtidigt ökar efterfrågan på soft adventures, bekväma och tillrättalagda There is a growing demand for environmentally friendly ways of transportation, and therefore the electric bicycle has been booming in Sweden. The electric bicycle is often used as means of transportation to and from work, but has potential to be used in other situations as well. The environmental impact caused by transportation during holidays has recently gained attention. At the same time the de

Due to its high vulnerability, permafrost is one of the key features studied in the field of climate change impacts. Permafrost is widespread in the Arctic region. The majority of the area underlain by permafrost is however difficult to access for in-situ monitoring and it is difficult to get an overview of the current state of permafrost in many areas. Permafrost modeling provides a solution whi