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BACKGROUND: Mean diffusivity (MD) and fractional anisotropy (FA) from diffusion MRI (dMRI) have been associated with cell density and tissue anisotropy across tumors, but it is unknown whether these associations persist at the microscopic level.PURPOSE: To quantify the degree to which cell density and anisotropy, as determined from histology, account for the intra-tumor variability of MD and FA in
BACKGROUND: Neurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is to provide the most comprehensive and up-to-date estimates of the global, regional, and national burden from neurological disorders.METHODS: We estimated prevalence, incidence, d
Importance: Prenatal exposure to phthalates has been associated with neurodevelopmental outcomes, but little is known about the association with language development. Objective: To examine the association of prenatal phthalate exposure with language development in children in 2 population-based pregnancy cohort studies. Design, Setting, and Participants: Data for this study were obtained from the
Intracerebral haemorrhage and small vessel ischaemic stroke (SVS) are the most acute manifestations of cerebral small vessel disease, with no established preventive approaches beyond hypertension management. Combined genome-wide association study (GWAS) of these two correlated diseases may improve statistical power to detect novel genetic factors for cerebral small vessel disease, elucidating unde
A gardener in Småland, southeastern Sweden, tells that her father cultivated a double daylily, Hemerocallis fulva, with variegated leaves in Stockholm in the mid 20th century. When she moved to Småland, 45 years ago, she brought a piece of his plant with her, and later on she has spread the plant to others. This daylily, known as "Kwanso Variegata", was first found in Japan in 1776, and since then
IMPORTANCE In age-related macular degeneration (AMD), rare variants in the complement system have been described, but their functional consequences remain largely unexplored. OBJECTIVES To identify new rare variants in complement genes and determine the functional effect of identified variants on complement levels and complement regulation in serum samples from carriers and noncarriers. DESIGN, SE
Recent emission legislation in the marine sector has emphasized the need to reduce nitrogen oxides (NOx) emissions as well as sulphur emissions. The fulfilment of emission legislation limits with conventional marine diesel oil (MDO) requires complex and expensive aftertreatment systems and in this framework lean burn pilot ignited dual fuel (diesel and natural gas) is revealed as one of the most s
It is well established that high ambient heat could cause congenital abnormalities resulting in miscarriage or stillbirth among certain species of mammals. However, this has not been systematically studied in real field settings among humans, despite the potential value of such knowledge for estimating the impact of global warming on the human species. This study sought to test the hypothesis that
Context. Parallaxes for 331 classical Cepheids, 31 Type II Cepheids, and 364 RR Lyrae stars in common between Gaia and the Hipparcos and Tycho-2 catalogues are published in Gaia Data Release 1 (DR1) as part of the Tycho-Gaia Astrometric Solution (TGAS). Aims. In order to test these first parallax measurements of the primary standard candles of the cosmological distance ladder, which involve astrom
Rätten till familjeåterförening stadgas i såväl EU:s Familjeåterföreningsdirektiv som i den svenska utlänningslagen. Principen om familjens enhet, allas likhet inför lagen och barnets bästa är principer av stor vikt inom både internationell, europeisk och svensk rätt. Trots principer som att familjen ska hållas samman och att det ska göras vad som är möjligt för att återförena splittrade familjer,The right to family reunification is regulated in both the Family Reunification Directive of the European Union and in the Swedish Aliens Act. The principles of the family as a unit, all individuals equality towards the law and the child’s best interests, are principles of high importance in International, European and Swedish law. There are obstacles in the Swedish law preventing many families fr
This thesis aims to examine whether archive pedagogy is a useful learning resource in school today, and if so, how this cooperation works in reality. We want to find out how the archive's educational resources are perceived by teachers and students, and where the possible obstacles may lay. By examining how teachers and students perceive the archive education, our study can contribute to bette
Background: Today, many companies use a cost-based and sometimes competition-based pricing approach. Since academia agrees that value based pricing is superior for creating profit, the problem is not in identifying an ideal pricing strategy, but to understand and facilitate the transformation process towards value-based pricing. Only a limited amount of research has so far been put on understandin
Water is a large part of life on earth and is also a large part of the human body which is why it is so important. Aquaporins are water channels that transports water through a process called trafficking. Aquaporin 2 is one of these aquaporins and with a faulty trafficking or mutations it could lead to nephrogenic diabetes insipidus and severe dehydration. Ezrin is a protein in the body which FERM
The textile product industry has many challenges and all designers creating products using textiles will have an impact on the environmental sustainability in the world. The project investigates state of the art textile product design today, the challenges of environmental sustainability in the future and how the designer plays a role in making a positive difference. Qualitative research was done
Sweden's compulsive laws are processed by social workers and there are no real guidelines for how the investigations should be assessed. It is up to the social worker to assess a case with the help of the law, the municipality’s policies, and the room for maneuver. The aim of this study was therefore to explore if social workers assess cases differently and what arguments they use in situation
Det finns många svårigheter med att tillverka livsmedelsprodukter som är emulsioner. Syftet med detta projekt var att utveckla en emulsion enligt krav som beställaren av produkten hade satt upp. En första utveckling av produkten skedde ungefär ett år tidigare, och den fortsatta utvecklingen baserades alltså på denna produkt. Det som hade blivit ett problem med den första utvecklade produkten var aIt is a difficult process to create a drinkable food product that is an emulsion. The aim with this project was to create one, containing ingredients on levels described by a customer. A product had been developed before, but resulted in a product that had viscosity that was too high, and the aim with this further development project was to keep the levels of the ingredients on a level according t
The ever increasing data rates in wireless communication require analog to digital converters (ADCs) with greater requirements on speed and accuracy, while being power efficient to prolong battery life. This dissertation contains an introduction to the field and five papers that focus on the continuous-time (CT) Delta-Sigma modulator (DSM) as ADC. Paper I analyses the performance degradation of d
Importance Active perinatal care increases survival of extremely preterm infants; however, improved survival might be associated with increased disability among survivors. Objective To determine neurodevelopmental outcome in extremely preterm children at 2.5 years (corrected age). Design, Setting, and Participants Population-based prospective cohort of consecutive extremely preterm infants born be
Indonesia has implemented national policies and legislations to encourage biofuel production as means to achieve energy security and self-sufficiency and to reduce reliance of fossil fuel reserves. However, there is still no clear road-map for the socio-technological transition. While acknowledging economic impediments, this case study investigates social and political obstacles to bioethanol prod
This study's primary objective was to understand how remittances from international labour migration influences the capabilities of Kenyan returnees from the Middle East. The study examined how migrants and their families used the money they sent home, what kind of education they got, how they got medical care, and how they started businesses. Sen's capacity approach and the new economics
