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Introduction: The main purpose of this study was to extract global values of oxygen extraction fraction (OEF) and cerebral metabolic rate of oxygen (CMRO2) in healthy volunteers, using magnetic resonance imaging (MRI) phase maps. The repeatability of the method was evaluated, and the age dependences of OEF and CMRO2 were analyzed. Material and methods: Phase data were acquired using a 3T MRI scann
Aims: To examine the separate associations of glycemic control and chronic kidney disease with hospitalization days over one year in patients with type 2 diabetes (T2D). Materials and methods: A cross-sectional study using retrospective data on T2D patients in Region Halland, Sweden, during 2020. Data from the Region Halland database included hospitalizations, emergency visits, primary care encoun
Energy efficiency and environmental questions have gained increased attention over the last decade. In combination with global warming and increasing cooling demands, the Swedish market for combined heating and cooling solutions such as ground source heat pumps expands. As it currently stands, the multi-family building market is highly dominated by district heating, while the market share of combi
BACKGROUND AND OBJECTIVE: Achieving adequate concentrations of beta-lactam antibiotics in patients with severe infections is challenging, and therefore therapeutic drug monitoring (TDM) would be optimal for guiding beta-lactam dosing, but is often limited by availability. UV/VIS spectrophotometry can quantify drug levels in saline, and if those levels truly reflect plasma concentrations, it could
BACKGROUND/AIM: Determining the causation of an injury in living individuals is a key task for forensic pathologists. However, little is known about sex-based differences in injury characteristics. The study aims to examine sex-based differences in single stab injuries to the trunk among assault survivors, to potentially identify injury patterns that could aid forensic assessment and help in the m
BACKGROUND: Early HIV diagnosis allows timely interventions to control HIV transmission. We have determined the proportion of recent infections among people living with HIV (PLHIV) enrolling to care in Ethiopia and identified factors associated with recent infection. METHODS: Participants (aged ≥ 15 years) newly enrolled in HIV care were recruited from urban clinics in central Ethiopia (2022-2024)
This study investigates the factors influencing the adoption and acceptance of cloud-based solutions within organizational contexts, emphasizing the strategic insights necessary for effective cloud migration. Cloud computing, marked by its scalability, has significantly transformed information technology landscapes. However, the adoption rates vary widely across industries, driven by diverse organ
The main monitoring method during labor is cardiotocography, CTG, which measures the fetal heartbeat, FHR, as well as the uterine contractions, TOCO. The CTG is a valuable tool in assessing the fetal status and it is evaluated intermittently by clinicians during the progress of the labor. However, abnormalities in the CTG are often non-specific which makes the interpretation difficult and inconsis
There is strong evidence that climate change has a direct impact on humans and extreme temperatures have been linked to negative health impacts and increasing mortality. The heat wave of 2018 caused up to 8.2% more deaths compared to the year before in Sweden, with higher impacts in other parts of the world. The fact that people spent almost 90% of their times indoors makes the indoor environment
The triple planetary crisis exerts high pressure on countries to transform their current economic system. The transition to a green economy is not only necessary to ensure sustainable development but also essential for countries to remain economically competitive. The neighbouring countries Panama and Costa Rica are both facing significant challenges under the green transition, despite their diffe
Background: The rapid increase in type 2 diabetes worldwide has mainly been attributed to lifestyle factors, including poor eating habits and physical inactivity. Type and quality of diet is a key factor in both prevention and treatment of type 2 diabetes. Aim: To investigate the association between diet quality and risk of type 2 diabetes. Methods and Subjects: This prospective study in the M
Lifestyle modifications could be crucial in preventing and managing type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVD), including diet and postprandial glycaemic control. Previous studies on the effects of polar lipids (PLs) on postprandial metabolic responses at Lund University have shown conflicting results. To reconcile these findings and contribute to the existing literature, th
Background: Dietary pattern analysis has gained particular interest, because it reflects the complexity of dietary intake. The aim of this study was to explore the associations between a posteriori dietary patterns, derived using a data-driven approach, and the risk of differentiated thyroid cancer (TC) in Europe. Methods: This investigation included 450,064 adults from the European Prospective In
BACKGROUND: Limited data are available on the incidence of mechanical complications after ultrasound-guided central venous catheterisation. We aimed to determine the incidence of mechanical complications in hospitals where real-time ultrasound guidance is clinical practice for central venous access and to identify variables associated with mechanical complications.METHODS: All central venous cathe
Nitrogenase is the only enzyme that can cleave the triple bond in N2, making nitrogen available for all lifeforms. Previous computational studies have given widely diverging results regarding the reaction mechanism of the enzyme. For example, some recent studies have suggested that one of the μ2-bridging sulfide ligands (S2B) may dissociate from one of the Fe ions when protonated in the doubly
Background: Arterial hemodynamic parameters derived from reservoir-excess pressure analysis exhibit prognostic utility. Reservoir-excess pressure analysis may provide useful information about an influence of altered hemodynamics on target organ such as the kidneys. We determined whether the parameters derived from the reservoir-excess pressure analysis were associated with the reduction in estimat
Background: Aggregation of lung cancer (LCa) in family members is well-documented. However, little is known on the familial risk of LCa when first-degree relatives (FDRs, parents or siblings) are diagnosed with LCa as a second primary malignancy (LCa-2). We aimed to investigate whether and to what extent a family history of LCa-2 was associated with an increased LCa risk. Methods: In this Swedish
