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DNA carries the genetic code of life, with different conformations associated with different biological functions. Predicting the conformation of DNA from its primary sequence, although desirable, is a challenging problem owing to the polymorphic nature of DNA. We have deployed a host of machine learning algorithms, including the popular state-of-the-art LightGBM (a gradient boosting model), for b
Aim of the studyRates of bystander CPR are increasing, yet mortality after out-of-hospital cardiac arrest (OHCA) remains high. The aim of this survey was to explore public knowledge and attitudes to CPR. Our hypotheses were that recent CPR training (< 5 years) would be associated with a high-quality response in a case vignette of OHCA with agonal breathing, and associated with an interest to becom
We present a microfluidic system to control the position of particles (polystyrene beads or astrocyte cells) in hydrogel droplets using bulk acoustic standing waves. Droplets comprising hydrogel precursor solution, photoinitiator and (bio-)particles were generated and acoustic forces focused the beads to the droplet center line. Droplets were cross-linked by exposure to UV-light. With the acoustic
This contribution reports a novel method for cell-supernatant separation inside nanoliter droplets with separation efficiencies for single cells of 100% at flow speeds of 2 mm/s. Cells are focused in nanoliter droplets using bulk acoustic waves before the droplet is split at a bifurcation into a supernatant- and a cell-containing droplet. The method enables upconcentration of cells, cell washing,
BackgroundDiagnosing sepsis remains a challenge because of the lack of gold-standard diagnostics. Since there are no simple, broadly accepted criteria for infection, there is a risk of misclassifying sepsis patients (sepsis mimics) among patients with organ failure. The main objective of this study was to investigate the proportion of non-infected patients (sepsis mimics) in ICU patients with pres
Designed as a system which, by transfer of knowledge and extended documentation, can act as one of many tools when it comes to dealing with situations containing violence, the SVARNE system may turn out to be an useful aid not only for people working with
The 2010s have raised questions about the influence of small central banks in an integrated economy. This thesis investigates the efficacy of the Swedish Riksbank and the effect of economic integration since the adoption of a floating exchange rate in 1993. Theoretically, I examine how financial integration and trade may impact the Mundell-Fleming trilemma. To investigate the impact of integration
Scholars on Europeanization generally agree that local level governments are somewhat Europeanized since they are affected by EU legislation. The debate between scholars rather revolves around how local level governments are Europeanized. This study finds itself at the centre of the debate and studies what aspects of Europeanization that are present in the local level governments in Sweden. T
This essay explores how a critical reading of the novel The Grapes of Wrath (1939) can inform teachers when discussing inequality issues in the ESL classroom. The main questions being investigated are how the novel The Grapes of Wrath reveals oppressive and unequal power relationships, and how a critical reading of the novel can be used when teaching and informing others about inequality. In this
This project explores the design of a modular, wall-mounted shelving system that merges the practicality of hardware storage with the refined aesthetic of contemporary furniture. Driven by an interest in modularity and metal as a design material, the project investigates how adaptability, sustainability and visual clarity can coexist in a single solution. The result is a system constructed in recy
