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Background: Nausea and vomiting in pregnancy (NVP) affects 50–80% of pregnant women and is correlated to the level of human chorionic gonadotropin (hCG). Hyperemesis gravidarum (HG) is a severe condition, with an incidence of 0.2–1.5%, characterized by consistent nausea, vomiting, weight loss and dehydration continuing after the second trimester. Aim: The aim of this systematic review was to inves
Anterior cruciate ligament (ACL) injury rates in female adolescents are increasing. Irrespective of treatment options, approximately 1/3 will suffer secondary ACL injuries following their return to activity (RTA). Despite this, there are no evidence-informed RTA guidelines to aid clinicians in deciding when this should occur. The first step towards these guidelines is to identify relevant and feas
Aging of the hematopoietic stem cell compartment is believed to contribute to the onset of a variety of age-dependent blood cell pathophysiologies. Mechanistic drivers of hematopoietic stem cell (HSC) aging include DNA damage accumulation and induction of tumor suppressor pathways that combine to reduce the regenerative capacity of aged HSCs. Such mechanisms do not however account for the change i
Emerging evidence suggests differential effects of therapeutic antibiotics on infant T cell responses to pathogens. In this study, we explored the impact of the treatment of mouse infants with amoxicillin and the human milk-derived antimicrobial HAMLET (human alpha-lactalbumin made lethal to tumor cells) on T cell responses to Streptococcus pneumoniae. Lung cells and splenocytes were isolated fr
Monoclonal antibodies are among the most promising therapeutic agents in modern medicine, yet their formulation into high-concentration solutions for subcutaneous self-administration poses a major challenge. A key obstacle is the marked increase in viscosity often observed under these conditions. To gain deeper insights into this phenomenon, coarse-grained models derived from soft matter physics h
It is now established that native language affects one's perception of the world. However, it is unknown whether this effect is merely driven by conscious, language-based evaluation of the environment or whether it reflects fundamental differences in perceptual processing between individuals speaking different languages. Using brain potentials, we demonstrate that the existence in Greek of 2 color
The article documents the case of South Africa's struggle to reconcile racially based poverty, a legacy of apartheid, and attempts to conserve the country's unique and important biodiversity. We present an analysis of KwaDapha, a small village in the iSimangaliso Wetland Park in northern KwaZulu-Natal, a protected area and UNESCO World Heritage Site, in terms of the capability approach. Despite So
The binding of a nitroxide spin-labeled analog of N-acetyllactosamine to galectin-3, a mammalian lectin of 26 kD size, is studied to map the binding sites of this small oligosaccharide on the protein surface. Perturbation of intensities of cross-peaks in the (15)N heteronuclear single quantum coherence (HSQC) spectrum of full-length galectin-3 owing to the bound spin label is used qualitatively to
Popular Abstract in Swedish Streptococcus pyogenes (GAS) är en viktig sjukdomsframkallande bakterie som orsakar alltifrån lindriga infektioner som halsfluss (tonsillit) och svinkoppar (impetigo) till livshotande djupa infektioner som nekrotiserande fasceit eller ”Toxic shock syndrom”. På grund av det snabba sjukdomsförloppet i de livshotande infektionerna har streptokockerna fått beteckningen ”mörA distinguishing feature of Streptococcus pyogenes (GAS) is their ability to resist phagocytosis in whole human blood in the absence of type-specific antibodies, a property that is dependent on the expression of the surface associated M proteins. A common characteristic of M proteins is their interaction with a variety of host proteins including the complement regulatory protein factor H (FH) and
Vi lärare på Litteraturvetenskapliga institutionen vid Lunds universitet har länge saknat ett arbetsmaterial när vi undervisat i hur man utför epikanalyser. Det har visat sig att Claes-Göran Holmbergs och Anders Ohlssons Epikanalys. En introduktion har fungerat utmärkt som lärobok och på ett enkelt sätt utrett de många teorier och metoder som kan utnyttjas i en analys. Men våra erfarenheter av epi
Popular Abstract in Swedish Spionen var under kalla kriget en gäckande gestalt som i egenskap av sin synliga osynlighet blev en orienteringspunkt för vardagliga fantasier. Han – för denna det kalla krigets emblematiska figur var oftast en han – blev i flera avseenden just en samtidens mittpunkt i vilken en tudelad världsbild synliggjordes. Mannen i mitten handlar om Spionen i svensk kallakrigskultThe aim of this thesis is to contribute to a broadening of perspectives on Cold War Sweden. It is a study not primarily of the explicit political events or debates, but of the everyday cultural narratives of the era. During the long 1950s, Swedish Cold War imagination was largely characterised by a determination to maintain total security in the response to the threats that loomed on all sides, an
Detta är en bok om vetenskapsfilosofi. En bok om mål, metod och moral – vetenskapsteori för sanningssökare. Boken har inte blivit till på en eftermiddag. Allt började någon gång på 1980-talet med en kurs i vetenskapsteori för hortonomer och landskapsarkitekter på Lantbruksuniversitetet i Alnarp. Denna kurs lärde oss mycket om äppelodling, jordpackning, skogsbruk och annat spännande. Under årens lo
Human galectins have functionally divergent roles, although most of the members of the galectin family bind weakly to the simple disaccharide lactose (Galss1-4Glc). To assess galectin-glycan interactions in more detail, we explored the binding of several important galectins (Gal-1, Gal-2, and Gal-3) on a glycan microarray containing hundreds of structurally diverse glycans. All three galectins exh
Popular Abstract in Swedish Den kontinent Skandinavien idag tillhör kallas Eurasia, men den kontinent vi ser idag har inte alltid funnits. Kontinenterna var inte bara sammanfogade på andra sätt, de har också rört sig över jordens yta (de långsamma med samma hastighet som naglar växer!), i platt-tektoniska processer. Innan uppkomsten av Eurasia har Skandinavien i omgångar tillhört andra konstellatiIn an attempt to reconstruct the pre-Caledonian cratonic margin of Fennoscandia, U-Pb geochronological and geochemical investigations have been performed on allochthonous orthogneisses in the northern Swedish Caledonides. The crystalline basement of the nappes have also been examined to further constrain the continuation of various chronologically defined orogenic belts. To constrain the global pa
During 2012 - 2013 a study to evaluate conventional X-ray procedures and patient doses in Klintzi and Novozibkov areas of Bryansk region, Russia, was conducted. X-ray operation parameters included quality assurance of equipment, collection of procedure parameters and clinical practice evaluation. Effective doses were calculated for each selected procedure and dose distributions were established. 7
I denna artikel analyseras muntligt gestaltade erfarenheter hos 27 överlevande efter kriget i nordvästra Bosnien under 1990-talet. Syftet är att dels beskriva hur de intervjuade framställer det sociala fenomenet «offerskap», dels analysera diskursiva mönster som medverkar i konstruktionen av kategorin «offer». Aktörernas anspråk på statusen «offer» skapar en konkurrens om offerrollen efter kriget.The aim of this article is to analyse verbally portrayed experiences of 27 survivors of the 1990’s war in northwestern Bosnia. My focus is on describing how the interviewees portray the social phenomenon of «victimhood» and on analysing the discursive patterns that contribute to construction of the category «victim». When, after the war, different actors claim this «victim» status, it sparks a com
This paper provides a systematic review of scholarly literature concerning the enforcement of children’s rights in the classroom context and school management. The literature review is based on a systematic review methodology the authors developed drawing on the methods and guidelines used in the medical sciences over the last 15 years. Forty-two articles published between 1990 and 2014 were selec
