Filetype
BACKGROUND: The NextFood Project ( www.nextfood-project.eu) started work in 2018 to identify 'Categories of Skills' that students should be equipped with to address the upcoming global challenges within agrifood and forestry disciplines, and involved concepts such as sustainability, technological adaptation and networking. This study is based on the initial skills and competencies mapping, but tak
Introduction: Evidence-based clinical practice guidelines drive optimal patient care and facilitate access to high-quality treatment. Creating guidelines for rare diseases such as haemophilia, where evidence does not often come from randomized controlled trials but from non-randomized and well-designed observational studies and real-world data, is challenging. The methodology used for assessing av
Tumour-induced osteomalacia is caused by tumorous production of fibroblast growth factor 23 (FGF23) leading to urinary phosphate wasting, hypophosphataemia and decreased vitamin D activation. The resulting osteomalacia presents with muscle weakness and bone pain but progresses to multiple pathological fractures. Patients often remain undiagnosed for years with severe physical, psychological and ec
Protein aggregation is a key process in the development of many neurodegenerative disorders, including dementias such as Alzheimer's disease. Significant progress has been made in understanding the molecular mechanisms of aggregate formation in pure buffer systems, much of which was enabled by the development of integrated rate laws that allowed for mechanistic analysis of aggregation kinetics. Ho
Recent studies have explored the influence of obesity and critical illness on ciprofloxacin pharmacokinetics. However, variation across the subpopulation of individuals with obesity admitted to the intensive care unit (ICU) with varying renal function remains unexamined. This study aims to characterize ciprofloxacin pharmacokinetics in ICU patients with obesity and provide dose recommendations for
Objective: To translate and cross-culturally adapt the Stroke Self-Efficacy Questionnaire (SSEQ) from English to Swedish and to evaluate psychometric properties of the questionnaire. Methods: A cross-sectional study design, where the translation followed a process including initial translation, synthesis, backward translation, expert committee, and pretest. Content validity was assessed using Cont
Digitalization and emergence of new technologies including Artificial Intelligence has shaped new organizational principles for the functioning of economies and societies globally. Technology has also changed the landscape for taxation and interactions between tax administration and taxpayers. Recently various models of electronic reporting and invoicing, split-payment mechanisms as well electroni
Taking point of departure in two black dolls that once belonged to Sophie Christine Oxholm and to the family of Clara Asenath Schultz, the article explores aspects of childhood and childcare in colonial homes. Both girls grew up in the Danish West Indies in the nineteenth century and were cared for by African Caribbean nannies – the likely makers of the dolls. Drawing on historical and literary so
This article examines limits to per capita living space (i.e. living smaller and/or sharing living space) as a measure for achieving sufficiency in housing. It studies the acceptance, motivation and side-effects of voluntarily reducing living space in five European Union countries: Germany, Hungary, Latvia, Spain and Sweden. Insights are derived from an extensive collection of qualitative empirica
Multiple myeloma (MM) is an incurable malignancy of plasma cells. Epidemiological studies indicate a substantial heritable component, but the underlying mechanisms remain unclear. Here, in a genome-wide association study totaling 10,906 cases and 366,221 controls, we identify 35 MM risk loci, 12 of which are novel. Through functional fine-mapping and Mendelian randomization, we uncover two causal
Children's time investments in various activities may be important for reducing socioeconomic status (SES) gaps in educational and mental health outcomes. Using detailed time use diaries of Australian children aged 4–14, we observe that children from low SES backgrounds spend more time on digital media and less time on out-of-school enrichment activities, organised or for leisure. We explain the S
It has been established across several contexts that political attitudes are informed by heritable factors. However, it remains unclear how much of the stability we observe in political attitudes can be ascribed to environmental factors and how much of the stability is due to genetics. In this paper we show, using a unique three-wave panel dataset of twins (N = 2471) spanning ten years, that both
