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The immune system has evolved to protect the human body against harmful invaders. At the same time, development of tolerance against self-derived and innocuous foreign antigens is of vital importance in order to avoid detrimental immune disorders. In allergic conditions, hypersensitivity is developed against harmless antigens, such as pollen. Dendritic cells (DCs) serve as a link between the innat

In this analysis of the retold experiences of 27 survivors of the war in northwestern Bosnia, the aim is to describe the informants’ portrayal of “war violence”, “sexual war violence”, “victimhood”, and “reconciliation” as a social phenomenon as well as analyzing the discursive patterns that contribute to constructing the category “victim” and “perpetrator”. The violence practice during the war is

The severity of urinary tract infections (UTIs) varies depending on the balance between the virulence of the infecting bacterial strain and the antibacterial host defense. Bacterial virulence is determined by a complex of factors in which bacterial adherence to the uroepithelium is the most important virulence factor, in addition to the production of toxins and the formation of biofilm. In immunoc

The purpose of this paper is threefold. Firstly, the paper introduces the One Triangle Three Parallelograms (OTTP) sampling strategy, which can be viewed as a way to index pixels from a given shape and image. Secondly, a framework for cascaded shape regression, including the OTTP sampling, is presented. In short, this framework involves binary pixel tests for appearance features combined with shap

The bacterial superantigen (SAg) staphylococcal enterotoxin A (SEA) is a potent inducer of CTL activity and cytokine production in vivo. To engineer SAg for cancer immunotherapy, we genetically fused SEA to a Fab fragment of the C215 tumor-reactive antibody. Strong reduction of lung metastasis was seen in mice carrying established lung metastases of the poorly immunogenic B16-C215 melanoma after F

This paper presents and discusses a method using a range of techniques for assessing sensorial perception of product design and interaction. Collectively denoted ‘Five Senses Testing’, the purpose of the method is to facilitate the assessment of sensory experience related to product design and product use. Furthermore, the outcomes of using the techniques inform product design development by conne

Noise control in buildings should aim at reducing disturbances caused by speech noise (i.e., improve speech privacy, speech intelligibility). Room acoustics can be controlled with high room absorption, high screens and bookcases, and sufficient masking sound. This research concerns as important aspect of room acoustic metrology, the ability to quantify the most relevant room acoustic parameters fo

Ice observations were made in the Rane River 1974-1978. Observations of formation of ice, growth of ice, critical velocities, hydrodynamic stability, supercooled water, ice production in rapids and breakup were theoretically analyzed. Depending on the water velocity an ice cover formed after 40-100 negative °C-degree-days. The growth of ice took place at a static growth when the water velocity was

Agricultural expansion and intensification have boosted global food production but have come at the cost of environmental degradation and biodiversity loss. Biodiversity-friendly farming that boosts ecosystem services, such as pollination and natural pest control, is widely being advocated to maintain and improve agricultural productivity while safeguarding biodiversity. A vast body of evidence sh

Metaphrasis: A Byzantine Concept of Rewriting and Its Hagiographical Products represents a first and authoritative discussion of rewriting in Byzantium. It brings together a rich variety of articles that treat the topic of hagiographical rewriting from various angles.The contributors discuss and comment on different kinds of texts in Greek and other languages, including Apophthegmata Patrum, Passi