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This work concerns an experimental study of pressure drop and heat transfer for turbulent flow inside a U-duct. Such duct geometries can be found in many engineering applications where cooling air extracts heat from hot internal walls of the duct, e.g., passage cooling inside gas turbine blades. Both friction factors and convective heat transfer coefficients were measured inside a U-duct for three
The Moving City: Processions, Passages and Promenades in Ancient Rome focusses on movements in the ancient city of Rome, exploring the interaction between people and monuments. Representing a novel approach to the Roman cityscape and culture, and reflecting the shift away from the traditional study of single monuments into broader analyses of context and space, the volume reveals both how movement
Mary Wollstonecraft is a writer whose work continues to provoke scholarly debate. But Wollstonecraft the historical figure often obscures her importance as a philosopher. Halldenius explores Wollstonecraft’s political philosophy, focusing on her treatment of republicanism and independence, to propose a new way of reading her work – that of a ‘feminist republican’. Wollstonecraft’s works of fiction
This chapter describes a personal aerosol sampler with size fractionation and time resolution that gives samples for elemental analysis. An impaction stage collects coarse particles and a filtration stage collects finer ones. Sampling in consecutive time intervals is performed on different impaction and filtration surfaces. These sampling surfaces corresponding, for example, to 15-min intervals, m
Gaia is ESA’s space astrometry mission with a foreseen launch date in early 2012. Its main objective is to perform a stellar census of the 1000 Million brightest objects in our galaxy (completeness to V=20 mag) from which an astrometric catalog of micro-arcsec level accuracy will be constructed. A key element in this endeavor is the Astrometric Global Iterative Solution (AGIS). A core part of AGIS
Proficiency in writing is a central graduate attribute of higher education. In practice, this means that students are expected to acquire both generic and discipline-specific writing skills that will be beneficial for their professional lives. Although the learning outcomes for many courses include the ability to express oneself in writing, a predominant function of writing is that of mere testing
Cosmological long-duration gamma-ray bursts (LGRBs) are thought to originate from the core collapse to black holes (BHs) of stripped massive stars. Those with sufficient rotation form a centrifugally supported torus whose collapse powers the GRB. We investigate the role of tidal locking within a tight binary as a source of the necessary angular momentum. We find that the binary orbit must be no wi
Purified, recombinant M12 protein from Streptococcus pyogenes CS24 has recently been demonstrated to bind human immunoglobulin G3 (IgG3). The binding site for IgG has been localized to an internal peptide encoded by a PvuII fragment of the gene emm12. We have investigated the ability of an isolated recombinant M12 protein consisting of the peptide encoded by the PvuII fragment to bind various mono
Positional cloning of the underlying genes for the rare syndrome autoimmune polyendocrinopathy candidadiasis extrodermal dystrophy (APECED) opened a new venue of research on the role of central tolerance in autoimmunity. The associated autoimmune regulator gene (AIRE), was found to be expressed in medullary thymus epithelial cells (mTEC) in both man and mice, and to control promiscuous expression
The estimated quantity of cement for construction and sealing purposes is around 9E5 kg in the planned Swedish KBS3 repository for nuclear waste. The highly alkaline cement pore fluid (pH > 12) may affect other components in the repository, and especially the bentonite buffer is of concern. In this study, we simulated possible interactions between cement and bentonite by contacting highly compacte
Early B cell factor (EBF)-1 is a transcription factor known to be of critical importance for early B lymphocyte development. EBF-1 has been shown to directly interact with and regulate expression of a set of genes involved in the functional formation of the preB cell receptor, but the dramatic phenotype observed in the EBF-1-deficient mice suggests that several additional genes are activated by th
The gene for protein D, a membrane-associated protein with specific affinity for human immunoglobulin D, was cloned from a nontypeable strain of Haemophilus influenzae. The gene was expressed in Escherichia coli from an endogenous promoter, and the gene product has an apparent molecular weight equal to that of H. influenzae protein D (42,000). The complete nucleotide sequence of the gene for prote
A technique of fluorescence multiplexing is described for analysis of the plasma membrane proteome of colorectal cancer cells from surgically resected specimens, enabling detection and immunophenotyping when the cancer cells are in the minority. A single-cell suspension was prepared from a colorectal tumour, and the mixed population of cells was captured on a CD antibody microarray. The cancer cel
