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Interleukin-1 beta and tumour necrosis factor-alpha impede neutral lipid turnover in macrophage-derived foam cells

Background: Pro-inflammatory cytokines can affect intracellular lipid metabolism. A variety of effects have been described for different cell types; hepatocyte lipid turnover pathways are inhibited during inflammation, whereas interleukin-1 beta (IL-1 beta) reduces intracellular cholesterol levels in fibroblasts. Levels of the pro-inflammatory cytokines IL-1 beta and tumour necrosis factor-alpha (

Planning for Solar Buildings in Urban Environments

Popular Abstract in Swedish Solenergi kommer att vara en av de viktigaste miljövänliga energikällorna i framtiden, vilket innebär ökat antal solpaneler (för el och värme) som integreras i våra hus men också som fristående produktionsanläggningar. När man planerar framtida hus och stadsdelar är det viktigt att skapa de bästa förutsättningarna för solenergi eftersom hus och stadsdelar finns kvar i fEnergy use in buildings accounts for a significant proportion of the total energy use in many countries. While past and current buildings have solely been energy consumers, future buildings will, besides using less energy, also need to produce (part of ) the required energy on site with renewables. Solar energy is generally very suitable for producing this on-site renewable energy. Although solar

Sufficient Efficiency? - A study on the World Trade Organization, The Doha Round and Agricultural Trade Issues in Developing Countries

In 2001 the Doha Round Talks was initiated by the World Trade Organization. Development was the overarching goal. For several developing countries with a comparative advantage in agriculture, trade with such products is seen as essential to economic growth and thus development. In order to spur this development it appears to be particularly important that developing countries have increased access

Designated Operational Entities. En legitim form av offentlig-privat governance inom ramarna för Clean Development Mechanism?

This thesis investigates the Designated Operational Entities (DOEs) under the Clean Development Mechanism (CDM) of the Kyoto Protocol. The DOEs serves as independent third-party auditors with the task of validating, verifying and certifying projects under the CDM. The majority of the DOEs are private entities. This is in line with the CDM objective of including the private sector in the climate ch

Global Governance? : A study of the relationship between NGOs, Human Rights and the UN

The role of Non-Governmental Organizations (NGOs) in world politics in general, and in the United Nations (UN) in particular, is increasingly gaining the attention by scholars of international law, political science and social anthropology. In this study the NGO-UN relation is investigated within the area of Human Rights. This is done by examining how NGOs are perceived by member states within the

Mångfald, makt och välvilja. En diskursanalys av intentioner och synsätt bakom integrationspolitiska åtgärder

The aim of my study is to critically analyse the discourse behind two different integration projects in Sweden, by using post colonial theory. My hypothesis is that many projects intended for increased integration includes a view of immigrants as the ?Others? which can be seen in how one talks about integration and culture in the discourse behind integration projects. The first of these two proje

Conclusion : Studying candidates, parties and voters. Lessons learned and new questions

In the concluding chapter, we outline the major findings from the eleven book chapters by connecting them to one another. We come back to the triadic delegation and accountability relationship between candidates, voters and parties that were developed based on principal–agent theory, and emphasise the most relevant findings of this book that inform this triad. The chapter also takes a critical sta

An Exact Ewald Summation Method in Theory and Practice

We present the widespread Ewald summation method in a new light by utilizing a truncated Gaussian screening charge distribution. This choice entails an exact formalism, also as particle mesh Ewald, which in practice is not always the case when using a Gaussian screening function. The presented approach reduces the number of dependent parameters compared to a Gaussian and, for an infinite reciproca

B-1 Cells Carry the Memory of Neonatal Immune Imprinting

Group A Streptococcus is a common pathogen that elicits a protective humoral response against the cell wall component GlcNAc. In this issue of Immunity, New et al. demonstrate the ability of long-lived B-1 cells to be programmed by microbial colonization and early life immunization to uniquely incorporate GlcNAc reactivity in mice, establishing their critical role in mediating neonatal immune impr

Fluorescence detection and assessment on tryptophan content of naked oat varieties in China

The experiment aims to assess the tryptophan content of main cultivars of naked oat in China, and analyze the correlation between contents of tryptophan and protein. Oat flour was hydrolysed with papain, the fluorescence intensity of hydrolysate was detected at excitation wavelength of 288 nm and emission wavelength of 352 nm, and finally the tryptophan content was quantitated according to standar

Repeated measures of Heparin-binding protein (HBP) and procalcitonin during septic shock : biomarker kinetics and association with cardiovascular organ dysfunction

BACKGROUND: Heparin-binding protein (HBP) is a neutrophil-derived pro-inflammatory protein, an inducer of endothelial dysfunction and vascular permeability and a promising prognostic biomarker in sepsis. This exploratory study aims to describe the kinetics of plasma HBP during septic shock and investigate an association between repeated measures of HBP concentration and cardiovascular organ dysfun

Dialectic of Two Cultures : Edward Albee, C. P. Snow, and Who's Afraid of Virginia Woolf? as Dramatized Epistemology

Since its publication and first performance, Edward Albee’s Who’s Afraid of Virginia Woolf? (1962) has often been interpreted with regard to the theme of truth and illusion. A less studied but nonetheless important aspect of the play concerns its relation to C. P. Snow’s concept of the “two cultures.” This article argues for the convergence of these two discussions, resulting in an epistemological

H2020 STRATOFLY PROJECT : FROM EUROPE TO AUSTRALIA IN LESS THAN 3 HOURS

As eluded in previous studies, with special reference to those carried out in the European framework, some innovative high-speed aircraft configurations have now the potential to assure an economically viable high-speed aircraft fleet. They make use of unexploited flight routes in the stratosphere, offering a solution to the presently congested flight paths while ensuring a minimum environmental i

How bird feeders help small species fight infection

Every day, throughout the world, people put huge quantities of food out at feeding stations for birds and other wild animals.Although we know that connecting with nature benefits human health and wellbeing, scientists still know relatively little about the consequences of providing food for wildlife. My team’s most recent research, however, has found that feeding garden birds in wintertime seems t