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Modeling of Hindered Diffusion in Gels

Popular Abstract in Swedish Ordet diffusion kommer från det latinska ordet diffu´sio som betyder spridning. Diffusion förekommer nästan överallt, även om man inte alltid kan se det. Exempelvis består all den luft som vi andas in av en mängd molekyler som diffunderar fram och tillbaka. Eller så kan det vara vattenmolekyler som diffunderar in till plåten på bilen och gör så att den rostar, eller varHindered diffusion occurs in the most different processes, as has been described in this thesis. It is very important to have an understanding of the influence of hindered diffusion on the mass transfer rate, especially when competing rate processes are acting simultaneously. Using mathematical modeling and simulation makes it possible to predict the effects of hindered diffusion. The systems that

Generation of human pluripotent stem cell reporter lines for the isolation of and reporting on astrocytes generated from ventral midbrain and ventral spinal cord neural progenitors.

Astrocytes play a critical role during the development and the maintenance of the CNS in health and disease. Yet, their lack of accessibility from fetuses and from the brain of diseased patients has hindered our understanding of their full implication in developmental and pathogenic processes. Human pluripotent stem cells (PSCs) are an alternative source to obtain large quantities of astrocytes in

Building rich and grounded robot world models from sensors and knowledge resources: A conceptual spaces approach

Robots interacting with other agents in rich information landscapes and complex dynamic physical environments require sophisticated and robust concept and knowledge management capabilities if they are to solve problems, communicate, learn and exhibit intelligent behaviours. In this paper we describe how conceptual spaces provide a powerful substrate upon which to build effective concept and knowle

Multiple Windows for Estimation of Locally Stationary Transients in the Electroencephalogram

In this paper, multiple windows, optimal for locally stationary processes (MW-LSP) are used to estimate the spectrogram of the electroencephalogram (EEG) where we focus on the ability to estimate transient frequency changes. A peak of known frequency was evoked in the EEG spectrum in a predetermined time interval, by using a 9 Hz flickering light. We investigate the multiple windows corresponding

Composing ad-hoc applications on ad-hoc networks using MUI

The MUI framework supports composition of ad-hoc applications from services available on ad-hoc networked devices. MUI is an open-ended framework, relying on migrating user interfaces and standardized data formats for connecting services, allowing existing devices to be connected to new devices without needing any pre-defined knowledge of their services. We illustrate the benefits of the approach

The Human Rights of Smuggled Migrants and Trafficked Persons in the Un Global Compacts on Migrants and Refugees

On 19 September 2016, the UNGA adopted the New York Declaration for Refugees and Migrants through which States committed to developing two compacts: one on refugees and one on safe, orderly and regular migration. The Zero Drafts of the compacts were published on 31 January 2018 and 5 February 2018, respectively. The move towards the discussion and adoption of the global compacts comes in part in r

IgG glycan hydrolysis by EndoS diminishes the pro-inflammatory properties of immune complexes from patients with SLE - a possible new treatment?

OBJECTIVE.: Systemic lupus erythematosus (SLE) is an autoimmune disease with chronic or episodic inflammation in several organ systems, related to the presence of circulating and tissue-deposited immune complexes (ICs) which stimulate leukocytes through FcγRs with subsequent inflammation. Treatment with EndoS, an IgG glycan hydrolyzing bacterial enzyme from Streptococcus pyogenes, has shown benefi

Den pedagogiska praktikens janusansikte: om det kommunikativa handlandets didaktiska villkor och konsekvenser

Popular Abstract in Swedish Villkoren för utbildning och undervisning förändras i väsentliga avseenden i takt med samhällets tilltagande komplexitet. Det är många gånger svårt för både lärare och elever att veta hur man på bästa sätt ska orientera sitt pedagogiska handlande. Med utgångspunkt från tre pedagogiska kontexter - grundskolan, de särskilda ungdomshemmen och grundskollärarutbildningen - p

Recognition of out-of-hospital cardiac arrest by medical dispatchers in emergency medical dispatch centres in two countries

Introduction Survival after out-of-hospital cardiac arrest (OHCA) remains low. Early recognition by emergency medical dispatchers is essential for an effective chain of actions, leading to early cardiopulmonary resuscitation, use of an automated external defibrillator and rapid dispatching of the emergency medical services. Aim To analyse and compare the accuracy of OHCA recognition by medical dis

Passive load control in backward-facing step flow by using chevrons

The ability of chevrons at the top edge of a backward-facing step to reduce downstream surface pressure fluctuations is investigated numerically. Three different chevron configurations are compared against a baseline case without chevrons. Low frequency reduction in the surface pressure fluctuations is observed for two of the configurations. The chevrons do not appear to have a significant effect

COASTAL EROSION AND BEACH NOURISHMENT IN SCANIA AS ISSUES IN SWEDISH COASTAL POLICY

I den här artikeln diskuteras kustpolicyförändringar i Sverige och deras dynamik, med stranderosion ochstrandfodring som exempel. Analysen baseras på Multiple Stream – modellen, som är en teoretisk modell förpolicyutveckling och agendasättning, utvecklad av samhällsvetaren John Kingdon (1984, 2003). Kustskydd ärinte ett separat policyområde i Sverige; åtgärder för att skydda allmän kust är ofta en

PET in the evaluation of head and neck cancer treatment - management of the neck

Popular Abstract in Swedish I gruppen huvudhalscancer ingår tumörer i övre luftvägar och svalg. Riskfaktorer för huvudhalscancer är rökning och alkoholöverkonsumtion. Under de senaste 20-30 åren har det skett en påtaglig ökning av insjuknandet, 4-5% per år, i det som kallas orofaryngeal cancer. Orofaryngeal cancer utgår från mellansvalget; mandlar, tungbas och mjuka gommen. Ökningen sammanfaller mThe treatment for head and neck squamous cell carcinoma (HNSCC) is surgery or (chemo)radiotherapy +/- surgery. Side effects related to therapy are long lasting and adversely affects quality of life. The incidence of oropharyngeal cancer is increasing and patients commonly present an advanced tumour stage with neck metastases at the time of diagnosis. The treatment protocol previously comprised rad

Gene-environment interactions for arsenic metabolism and metal-related oxidatively generated DNA damage

Popular Abstract in Swedish Arsenik (As) finns i grundvatten på många platser i världen, och mer än 100 miljoner människor världen över exponeras dagligen för As via dricksvatten. Kronisk exponering för As kan orsaka bl.a. cancer, hjärt-kärlsjukdom och diabetes. När As omsätts (metaboliseras) i kroppen bildas flera olika omsättningsprodukter (metaboliter) emellan vilka giftigheten skiljer sig åt. Over 100 million people around the world are exposed to high concentrations of arsenic (As) in drinking water, associated with a number of adverse health effects such as skin, lung and bladder cancer, vascular diseases and diabetes. In humans, As is metabolized via alternating reduction and methylation reactions, from inorganic As (iAs) into monomethylated (MMA) and dimethylated As (DMA). The most

Molecular Classification of Bladder Cancer

Popular Abstract in Swedish Cancer i urinblåsan är ett stort hälsoproblem i Sverige och världen. Det är den femte vanligaste cancerformen i Sverige och är den som belastar sjukvården med högst kostnader per patient. Ungefär tre fjärdedelar av de drabbade är män och patienterna är oftast kring 60-80 år gamla. Den behandling vi idag kan erbjuda en person som drabbas av blåscancer har inte förändratsDecisions in the treatment of bladder cancer today are based on clinical and pathological risk variables such as tumor stage and tumor grade. The importance of these conventional risk variables is well documented since more than 10 years, and they are used routinely in the clinics. Over the last ten years, cancer research has seen a gradual transition towards personalized medicine, i.e. the exploi

Escalation: Explorative studies of high-risk situations from the theoretical perspectives of complexity and joint cognitive systems

Popular Abstract in Swedish I högrisksystem såsom sjukvården är det frestande att härleda såväl framgång som motgång till enskilda individer. Vi prisar hjälten Dr. House för framgångssagor och vi drar syndabocken SOS-sköterskan inför domstol för att inte ha uppfattat allvaret i en specifik situation. Den enskildes professionalitet, erfarenhet och klokskap används som förklaringsmodeller för framgåThe main aim of the research is to explore different aspects of organisational resilience in escalating situations, with an investigation of both theoretical and practical implications. From the platform of an explorative approach, this study makes use of naturalistic research in the domain of health care and experimental simulation studies, in order to establish a broad theoretical framework vis-