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Regulating genetic engineering guided by human dignity, not genetic essentialism

How might a liberal democratic community best regulate human genetic engineering? Relevant debates widely deploy the usually undefined term “human dignity.” Its indeterminacy in meaning and use renders it useless as a guiding principle. In this article, I reject the human genome as somehow invested with a moral status, a position I call “genetic essentialism.” I explain why a critique of genetic e

Association of prenatal ambient air pollution exposure with placental mitochondrial DNA copy number, telomere length and preeclampsia

Background: Studies have shown that ambient air pollution is linked to preeclampsia (PE), possibly via generation of oxidative stress in the placenta. Telomere length and mitochondrial DNA copy number (mtDNAcn) are sensitive to oxidative stress damage.Objective: To study the association between prenatal exposure to ambient nitrogen oxides (NOx, a marker for traffic-related air pollution), and PE,

From Edith Carlmar to Iram Haq: Women in the Norwegian Film Industry

Norway is one of the best countries in the world when it comes to gender equality, ranking in second place only behind Iceland in the 2018 Global Gender Gap Report. The film industry, however, is and has always been dominated by men, and change in this field has been quite slow—at least until the last decade. Operating in a small country, with 5.3 million inhabitants in 2019, the industry is depen

Cancer recurrence and lethality are enabled by enhanced survival and reversible cell cycle arrest of polyaneuploid cells

We present a unifying theory to explain cancer recurrence, therapeutic resistance, and lethality. The basis of this theory is the formation of simultaneously polyploid and aneuploid cancer cells, polyaneuploid cancer cells (PACCs), that avoid the toxic effects of systemic therapy by entering a state of cell cycle arrest. The theory is independent of which of the classically associated oncogenic mu

Orbital Modification of the Himalia Family during an Early Solar System Dynamical Instability

Among the irregular satellites orbiting Jupiter, the Himalia family is characterized by a high velocity dispersion dv of several hundred m s-1 among its members, inconsistent with a collisional origin. Efforts to account for this through internecine gravitational interactions do not readily reproduce this feature. Here, we revisit the problem in the context of recent cosmogonical models, where the

Out-of-hospital cardiac arrest at place of residence is associated with worse outcomes in patients admitted to intensive care : a post-hoc analysis of the Targeted Temperature Management trial

BACKGROUND: The majority of out-of-hospital cardiac arrests (OHCAs) occur at place residence, which is associated with worse outcomes in unselected prehospital populations. Our aim was to investigate whether location of arrest was associated with outcome in a selected group of initial survivors admitted to intensive care.METHODS: This is a post-hoc analysis of the Targeted Temperature Management a

Is It Possible to Reduce the Number of Today’s Thermoplastics? - An Investigation of the Swedish Plastic Industry

Plastic’s unique properties are vital for a sustainable future, but its excessive global use signifies consumer society’s wastefulness, often found in short-lived products. Plastic development has overlooked recycling needs, resulting in low material recycling due to a wide array of plastic types with varying additives, leading to recycling challenges. Research focused on thermoplastics aims to re

Från manifest till fredsavtal: genus och inkludering i The Good Friday Agreement. En kvalitativ innehållsanalys av Northern Ireland Women’s Coalition’s manifest och The Good Friday Agreement

Den här studien undersöker i vilken utsträckning som Northern Ireland Women’s Coalition (NIWC) bidrog till att göra genus centralt i fredsprocessen i Nordirland under slutet av 1990-talet, samt hur teorin gender centrality av Fionnuala Ní Aoláin kan interpreta fallet. Utgångspunkten i studien är kvinnors historiska exkludering från den Nordirländska politiken och NIWC:s unika roll som kvinnor i fr

Defining Remanufacturing: A Key Business Strategy Advancing Industrial Circularity

Remanufacturing is a key strategy in the circular economy, enabling substantial product value retention. However, inconsistent definitions across standards and legislation hinder global trade, core recovery and market acceptance. This study examines how remanufacturing is defined in laws and standards, and how these definitions impact industry practices. Through a literature review of key existing

Living composites : mycelium biofabrication and the evolution of design

This chapter examines the integration of living materials into architectural design, focusing on the use of mycelium composites formed through fungal biotransformation. As architecture faces increasing demands for environmental responsibility, material innovation has turned toward biological systems capable of replacing high-impact construction materials. Mycelium, the filamentous body of fungi, o