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Purpose The aim of this study was to find clinically relevant MIBG-avid metastatic patterns in patients with newly diagnosed stage 4 neuroblastoma. Methods Diagnostic I-123-MIBG scans from 249 patients (123 from a European and 126 from the COG cohort) were assessed for metastatic spread in 14 body segments and the form of the lesions: "focal" (clear margins distinguishable from adjacent background
The 2030 Agenda which was established in 2015 by the United Nation contains 17 goals for a sustainable future. The implementation of the 2030 Agenda reaches out to all levels of society, both nationally, regionally and locally. For a successful implementation, the directive and control of the 2030 Agenda must be clearly communicated and well understood by the implementer. Moreover, recent studies
This study has aimed to explore how domestic violence service practitioners assess cases of predominantly non-physical violence against women in intimate partner relationships. The study examined practitioners in South England, United Kingdom, and New South Wales, Australia, adopting a generic purposive sampling. A qualitative approach was applied, using semi-structured interviews guided by a vign
The purpose of this thesis is to investigate what measures Baltic coastal States may take under international law to respond to the Russian shadow fleet and to the deliberate damage to submarine cables and pipelines in the Baltic Sea. The thesis addresses three research questions concerning the available legal measures and the extent to which existing international legal frameworks are sufficient
Denna undersökning rör frågan om vilket inflytande förkastningarna i de tektoniska Polotsk- Kurzeme och Småland-Blekingezonerna utövat på det överlagrande sedimenttäckets och den nutida topografins utbildning. Syftet var att bestämma karaktären av denna påverkan och dess tänkbara orsaker. De huvudsakliga undersökningsområdena utgjordes av Polotskdelen av Polotsk-Kurzeme deformationszonen i norra VThis is a study of the influence of the crystalline basement faults of the Polotsk-Kurzeme and the Småland-Blekinge Deformation Zones on the development of the sedimentary cover and the formation of the present topography. The purpose is to define the character and possible causes of this influence. The key target areas of this study are the Polotsk part of the Polotsk-Kurzeme Deformation Zone in
In this study I have examined which conditions that play a role in the conservation of natural environment. The results in this paper have been analysed from interviews that I have conducted with conservation officers working with conservation efforts in local municipality's in southwest Skåne, Sweden. In the process, I have come to the conclusion that the nature conservation the conservation
To investigate why people live in areas at high risk of floods, a qualitative case study was carried out in the areas around Akuressa, in southwest Sri Lanka. Data col- lection consisted mainly of semistructured interviews with local residents and government officials. The purpose was to study why people live in areas at high risk of floods, by looking beyond the purely physical aspects of living
Smallholder-based, sustainable, agricultural intensification is increasingly put forth as a development pathway that is necessary to improve farmer's livelihoods, enhance productivity and engender a surplus that can be used to feed growing urban areas across sub-Saharan Africa. The following article examines trends in yields for Africa's largest staple crop – maize – among smallholder farmers in s
In this perspective article, we provide recommendations for strengthening the policy framework for protecting the Baltic Sea from agricultural nutrient pollution. The most striking weakness is the lax implementation of prescribed abatement measures, particularly concerning manure management, in most countries. Institutions of the EU should also be leveraged for achieving Baltic Sea Action Plan (BS
In order to meet the increasing needs of housing and services in urban areas, cities are densified. When densifying a city, it is important to provide good living conditions while maintaining a low environmental impact. To ensure this, the urban planning process should include simulations of e.g. noise and daylight conditions. In this paper we describe a newly started projected directed towards th
This paper uses an analytical framework of multi-level and multi-phase perspectives to explore low carbon transition pathways for the UK road transport system. The work draws on the impact made by the national (UK) and regional (EU) low carbon policy instruments on the UK road sector. The results show that the transformation pathway, which is at the take-off phase on a large scale, is the only ful
Sensitizing capacities and cross-reactivity patterns of some diisocyanates and amines using the guinea-pig maximization test. Can p-phenylenediamine be used as a marker for diisocyanate contact allergy?
BACKGROUND: Detailed assessments of mortality patterns, particularly age-specific mortality, represent a crucial input that enables health systems to target interventions to specific populations. Understanding how all-cause mortality has changed with respect to development status can identify exemplars for best practice. To accomplish this, the Global Burden of Diseases, Injuries, and Risk Factors
Sea salt aerosol particles are highly abundant in the atmosphere and play important roles in the global radiative balance. After influence from continental air, they are typically composed of Na+, Cl-, NH4+, and SO42- and organics. Analogous particle systems are often studied in laboratory settings by atomizing and drying particles from a solution. Here, we present evidence that such laboratory st
Paperboard is a thin and lightweight material made of cellulose fibers and it is an important component in packaging material where it provides stiffness and rigidity. The scope of this work is the development of continuum models, and its numerical treatments, for simulating the processes of converting paperboard into packages. The thesis begins with a general introduction to paperboard and a revi
Granath A, Norrby-Teglund A, Uddman R, Cardell L-O. Reduced iNOS expression in adenoids from children with otitis media with effusion. Pediatr Allergy Immunol 2010: 21: 1151-1156. © 2010 John Wiley & Sons A/S Nitric oxide (NO) is a key mediator in the local immune response of human airways. Inducible NO-synthases (iNOS), and endothelial NO-synthases (eNOS) are two enzymes known to regulate its
The microscopic observation of lung tissue is challenging due to its fragile nature. Xylene and isopropanol are common tissue-clearing reagents used before paraffin embedding, yet no studies have compared these two reagents in lung tissue processing. Due to the well-known health risks xylene could introduce to operators, as well as its environmental hazards, it has long been desired that a less ha
‘Visibility’ is a concept often used in EU terminology as a means to advancing the EU’s reputation and standing in the world. Projections of EU visibility reveal changing conditions for international recognition where being seen is highly valued. This chapter examines the link between EU foreign policy, digitalization and public diplomacy, and especially the role of visibility in European Union (E
