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The purpose of the study has been to gain an understanding of how socio-cultural structures and gender norms affect young women’s leadership possibilities. This has been explored through a qualitative case study focusing on how young women leaders, working with sexual and reproductive health rights issues, experience and pursue leadership in Zimbabwe. A theoretical framework based on contextual an
Populärvetenskaplig sammanfattning Genen MYCN kodar för N-Myc, ett protein som fungerar som transkriptionsfaktor, det vill säga det kontrollerar vilka gener som transkriberas aktivt från DNA till RNA. Många neuroendokrina tumörer, speciellt neuroblastoma, uppvisar ofta onormalt höga nivåer av N-Myc, och eftersom N-Myc startar transkriptionen av många gener som är viktiga för cellens delning, tillvThe gene MYCN encodes a transcription factor with a fundamental role in many neuroendocrine tumors, especially neuroblastoma. The gene and protein are very similar to the closely related c-Myc protein, except for the 3´untranslated region (3´UTR), suggesting that it may be an important factor in determining their very different expression pattern at the post-transcriptional level. MicroRNA (miRNA)
I Sverige drabbas omkring 300 barn av cancer varje år och majoriteten av dem är bara fyra-fem år gamla när de får sin diagnos. Omkring två tredjedelar av barncancerdiagnoserna utgörs av leukemier, lymfom och hjärntumörer, medan den sista tredjedelen är olika solida tumörformer som njurtumörer och nervvävnadstumörer i buken. Cancersjukvårdens utveckling under de senaste årtiondena har medfört en avPurpose: The purpose of this study was to evaluate the impact of including PET (Positron Emission Tomography) in the process of pediatric radiation therapy planning. The aim was to study the effect on target volumes and how this in turn affects the resulting treatment plans. This study also aims to compare the estimated risks of various long-term complications and how the use of PET influences the
Emergency planning is required to respond to the increasing wildfire threat. A part of this is to assess a community’s capacity to move to a safe place during wildfires. This can be achieved by calculating the time it takes for a community to evacuate from an at-risk area to a relatively safe place. Simple approaches, such as the commonly used engineering calculation, may provide access to a broad
This thesis investigates the effectiveness of step size control in the numerical simulation of Stochastic Differential Equations (SDEs). The study is divided into a theoretical exploration and a series of numerical experiments. The theoretical section introduces key definitions and theorems, delves into the properties of Brownian motion, and examines the conditions under which solutions to SDEs ca
The future of agriculture depends on healthy soils, but soils are degrading within dominant agricultural systems, also in Denmark. Pioneer farmers seek a sustainable transition towards soil-centered management. However, reinforcing feedback loops in current agriculture is blocking such a transition. Founded in emancipatory social science and critical utopian action research, this thesis, in collab
Regularly described as hotspots for marine life, seamounts are important foraging grounds for marine predators. In surface waters over seamounts, diel vertically migrating organisms can be aggregated, making seamounts potentially attractive and profitable food sources for predators such as seabirds. Still, the potential association between seabirds and seamounts has seldom been described and littl
This project uses proton-proton collision data from the ALICE experiment at CERN to investigate the differences between three ways to classify events, known as event shape classifiers. The event shape classifiers that were investigated are RT , spherocity and flattenicity. The motivation behind this is the consistent use of these classifiers to select events when investigating the heavy-ion like
It is a common practise to quote option prices using their BlackScholes implied volatility. A volatility surface describes an options implied volatility as a function of the strike price and time to maturity. It can be used as a tool for hedging but also valuation when prices are not directly observable. The short-term evolution of this surface has been described by a variety of apocryphal rules.
This thesis work is part of a larger project with final goal to be able to measure the oxygen concentration in the lungs of infants, using non-invasive laser spectroscopy. This thesis is specifically dealing with simulations of light transport through the upper body of infants, as well as constructing a tissue-like model (phantom) that can be used in experiments. The goal is to use these simulatio
Data compression methods allow more data to be stored within a certain storage framework while still keeping the characteristics of the data in question. At the Large Hadron Collider on the grounds of CERN in Switzerland, limited data storage capability is and has always been an urgent problem. At the ATLAS experiment, one technique which allows researchers to save more data within the same storag
Planning for capacity in not just the production, but also in the supply chain, is important. Strategic long-term planning for the supply chain will affect how the company will be able to meet the demand. This Master Thesis will focus on the capacities within the supply chain at PolyPeptide and how they could be planned for in the future. PolyPeptide is a company that manufactures active pharmaceu
Matrix functions and their applications play an important role in different fields of science and engineering. The matrix exponential is one of the most important and extensively used function of matrices. The computation of the exponential of a matrix is an interesting topic that has been extensively studied over the years. There are several ways computing the matrix exponential but there is a pu
We study a 1+1 dimensional Yang-Mills model in the light-cone gauge (the ’t Hooft model). The colour group is SU (N ) and we study the limit N → ∞, the limit is taken such that g²N is kept constant. In this limit the only contributing diagrams are planar diagrams without gluon-gluon interactions. Using this, it is shown that there are no free quarks in this model. The bound state wave equation is
Embedded systems are hard to debug and the field of control software testing is relatively unexplored. Progress in these areas could provide better testing heuristics and safer systems. More specifically, hardware emulation is a potentially powerful tool that can help improve the speed and quality of the development cycle. Therefore, this study developed a hardware emulator for supporting embedded
This work presents the first data from a calculation engine for synchrotron Microbeam Radiation Therapy (MRT) implemented in the EclipseTM Treatment Planning System from Varian Medical Services. The calculation engine constitutes a simple pencil beam algorithm estimating ‘peak’ dose and of Monte Carlo simulated Peak Valley Dose Ratios (PVDRs) that are used to obtain ‘valley’ dose. The aim of this
The number of devices connected to the Internet is rapidly increasing. Especially the number of Internet of Things devices. These devices contain software which, like any other software, needs to be updated. With the great amount of devices to update, this calls for a manageable updating solution which does not depend on user interaction. In this thesis we present a solution to dynamically update
The aim of this study was to optimize a function starch-ethyl cellulose film for targeting the therapeutically active substance to the colon in the disease state for patients suffering from inflammatory bowel diseases. This study includes: • The preparation of the polymeric films and the investigation of the characterization (for example mechanical properties, water uptake, dry mass loss, and mic
