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The dynamic regulation of ligand binding is considered crucial for integrin function. However, the importance of activity regulation for integrin function in vivo is largely unknown. Here, we have applied gene targeting to delete the GFFKR sequence of the lymphocyte function-associated antigen-1 (LFA-1) alpha(L) subunit cytoplasmic domain in mouse germline. Lymphocytes from Lfa-1(d/d) mutant mice
In this paper, multiple windows, optimal for locally stationary processes (MW-LSP) are used to estimate the spectrogram of the electroencephalogram (EEG) where we focus on the ability to estimate transient frequency changes. A peak of known frequency was evoked in the EEG spectrum in a predetermined time interval, by using a 9 Hz flickering light. We investigate the multiple windows corresponding
The authors of the best-selling book PID Controllers: Theory, Design, and Tuning once again combine their extensive knowledge in the PID arena to bring you an in-depth look at the world of PID control. A new book, Advanced PID Control builds on the basics learned in PID Controllers but augments it through use of advanced control techniques. Design of PID controllers are brought into the mainstream
Popular Abstract in Swedish Det finns ett stort behov av molekyler eller reagenser för korrekt och snabb diagnos och/eller behandling av sjukdom. På laboratorier används särskilda verktyg för att ta fram sådana reagenser. Verktygen utgörs ibland av levande organismer, som t ex bakterier och virus, och kallas bioteknologiska verktyg. Ett av dessa verktyg baseras på användandet av en speciell typ avPhage display technology is a biotechnological tool that can be used to obtain molecules/reagents able to discriminate between target molecules. Reagents with such features can be used in diverse settings like biological chemistry, diagnostics and in therapeutic applications. Phage display technology is based on the use of recombinant DNA technology, bacteria and a special kind of bacterial virus,
A joint palaeomagnetic and Ar-40/Ar-39 study has been performed on two olistolithic blocks from the Cabrieres Wildflysch in the Montagne Noire region of the Massif Central in France. There, andesitic volcanic and volcaniclastic rocks of Llanvirn-Early Caradoc age (ca 470-458 Ma) occur. Despite extensive secondary alteration, destruction of the dominant magnetic mineral phase and Ar-40/Ar-39 whole
The envelope process is an analytical tool often used to study extremes and wave groups. In an approach to approximate the first passage probability for the underlying response the average number of envelope crossings is used to obtain an upper bound. In the first part of the paper, we review the approach as well as give a brief account of the previous results with some focus on the contribution
This article sets out to describe and explain the events that led, in the summer of 1967, to political chaos and near civil war in many parts of China. It links the violence on the ground to statements and policies formulated at the highest levels of the CCP and sets out to show how and why Mao Zedong himself must bear direct personal responsibility for what stands out as one of the darkest chapte
BACKGROUND: Neutralizing antibody assessments play a central role in human immunodeficiency virus type-1 (HIV-1) vaccine development but it is unclear which assay, or combination of assays, will provide reliable measures of correlates of protection. To address this, an international collaboration (NeutNet) involving 18 independent participants was organized to compare different assays. METHODS: Ea
The article provides an overview of ongoing research and key characteristics of Cognitive Semiotics, an emerging field dedicated to the transdiciplinary study of meaning, involving above all researchers from semiotics, linguistics, developmental and comparative psychology and philosophy. The combination of the following features distinguishes it from other synthetic approaches: (a) integration of
Cerebral ischemia that develops after subarachnoid hemorrhage (SAH) carries high morbidity and mortality. Inflammatory mediators are involved in the development of cerebral ischemia through activation of the mitogen-activated protein kinase pathway. We hypothesized that blockade of the MAPkinase/ERK (MEK)/extracellular signal-regulated kinase (ERK) pathway upstream with a specific raf inhibitor wo
Background. The estimation of glomerular filtration rate (GFR) is one tool to detect renal disease. The most used biomarker remains serum creatinine and the European Kidney Function Consortium (EKFCcrea ) equation is the most validated in Europe. More recently, cystatin C has been proposed as a biomarker. We studied the performances of the EKFC equations in a large cohort of subjects according to
SKOGH 21 maj 2021 GENUS- OCH KVINNO- HISTORIA I DAG S K O G H , S V E R I G E S K V I N N O - O C H G E N U S H I S T O R I K E R , B J U D E R I N T I L L : 2 1 m a j k l . 1 0 . 0 0 - 1 6 . 1 5 p å Z o o m . Ö p p e t f ö r a l l a ! A n m ä l a n / r e g i s t r e r i n g g ö r s h ä r Temadagen är ett samarbete mellan SKOGH, genushistoriska seminariet vid Lunds universitet, genushistoriska sem
https://www.cors.lu.se/sites/cors.lu.se/files/2021-05/SKOGH%2021%20maj%202021.pdf - 2026-07-17
Steck_et_al-2017-Pediatric_Diabetes.pdf OR I G I N A L A R T I C L E Residual beta-cell function in diabetes children followed and diagnosed in the TEDDY study compared to community controls Andrea K. Steck1 | Helena Elding Larsson2 | Xiang Liu3 | Riitta Veijola4 | Jorma Toppari5,6 | William A. Hagopian7 | Michael J. Haller8 | Simi Ahmed9 | Beena Akolkar10 | Åke Lernmark2 | Marian J. Rewers1 | Jef
https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-04/2017%20Steck_et_al.%20Pediatric_Diabetes.pdf - 2026-07-17
Denna uppsats syftar till att analysera statsansvar för folkmord, och gör detta mer specifikt genom att undersöka frågan om ansvar för medhjälp till folkmord samt mens rea elementet i folkmordsdefinitionen. År 2007 meddelade ICJ sin dom i the Genocide case, där en av de centrala frågorna för domstolen var ifall en stat kunde hållas ansvarig för folkmord under Folkmordskonventionen. ICJ konstateraThis thesis seeks to analyze the international responsibility of states for genocide, and more particularly does so by looking closer at complicity in genocide and the mens rea element of the definition. In 2007 the ICJ rendered its judgment in the Genocide case, where one of the key issues before the Court was whether a state could be held responsible for genocide under the Genocide Convention.
In the West Bank, a context of protracted displacement and institutional fragmentation, internally displaced persons remain structurally excluded from both humanitarian and national protection systems. Amid fragmented aid architecture and legal ambiguity, the Humanitarian-Development-Peace Nexus has been promoted as a framework for institutional coherence. Yet, it remains mired in a contested spac
As global supply chains become increasingly vulnerable due to geopolitical instability, rising protectionism, and sustainability pressures, the trend of reshoring has emerged as a strategic response among multinational enterprises (MNEs). This thesis explores the drivers behind the reshoring decisions of seven Swedish MNEs and examines the entry modes (EMs) through which these firms implement thei
Brevmall JUD D40/ Litteraturlista Litteraturlistan gäller ett (1) år efter avslutat kurstillfälle Humaniora och teologi Centrum för teologi och re l ig ionsvetenskap Litteraturlista för JUD D40 Mellan kontinuitet och förändring - judendomen i Sverige och världen, 7,5 hp, sommaren 2021 fastställd av studierektor 2021-04-19 Böcker Rosenstein, Marc J., Turning Points in Jewish History, Lincoln: Unive
https://www.ctr.lu.se/media/utbildning/dokument/kurser/JUDD40/20211/JUD_D40_Litteratur.pdf - 2026-07-17
Polycyclic aromatic hydrocarbons (PAHs) of molecular mass (MM) 302 Da comprise numerous structural isomers that are of high concern for human health. Because of their multiplicity, low abundance in the environment, and limited availability of authentic standards, their occurrence, composition, and environmental health risk remain not well characterized. Here we extend the characterization of MM 30
