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Purpose: A multimodal artificial intelligence (MMAI) biomarker was developed using clinical trial data from North American men with localized prostate cancer treated with definitive radiation, using biopsy digital pathology images and key clinical information (age, PSA, and T-stage) to generate prognostic scores. This study externally validates the biomarker in a prospective, real-world dataset of

BACKGROUND: Atrial fibrillation (AF) is suggested to be associated with venous thromboembolism (VTE) and might thereby play a role in the development of chronic thromboembolic pulmonary hypertension (PH). By elevating left-sided filling pressure and promoting atrial myopathy, AF may also play a role in the development of postcapillary PH. We aimed to investigate the association between AF, with or

Detta arbete utgör magisterexamensarbete inom utveckling av betongstommar i flervånings- hus. Under de senaste åren har allt större intresse fokuserats på byggsektorns låga produktivitetsutveckling, höga kostnader, byggnadsvård, oförmåga att ta till sig befintlig kunskap och dåliga lönsamhet. Några stora byggprojekt har dessutom fått stort utrymme i media till följd av bl.a. omfattande byggfel. De

Female survivors of childhood central nervous system (CNS) tumors experience an increased risk of infertility and various pregnancy complications. We aimed to explore whether the incidence of inguinal hernia could be higher in offspring of female CNS tumor survivors as compared to the general population. Girls who were younger than 15 years of age and diagnosed with CNS tumors between 1958 and 201

PURPOSE: A growing number of young patients with central nervous system (CNS) tumour survived for more than five years. However, these long-term survivors might be at risk of multiple late effects thus leading to a higher risk of late mortality. We aimed to explore the risk of late mortality and the pattern of mortality among long-term survivors of childhood or adolescent CNS tumour.METHODS: We id

Checkpoint blockade therapies that reactivate tumour-associated T cells can induce durable tumour control and result in the long-term survival of patients with advanced cancers1. Current predictive biomarkers for therapy response include high levels of intratumour immunological activity, a high tumour mutational burden and specific characteristics of the gut microbiota2,3. Although the role of T c

Filamentous fungi play a key role as decomposers in Earth’s nutrient cycles. In soils, substrates are heterogeneously distributed in microenvironments. Hence, individual hyphae of a mycelium may experience very different environmental conditions simultaneously. In the current work, we investigated how fungi cope with local environmental variations at single-cell level. We developed a method based

The non-equilibrium dynamics of electrons and nuclei govern the function of photoactive materials. Disentangling these dynamics remains a critical goal for understanding photoactive materials. Here we investigate the photoinduced dynamics of the [Fe(bmip)2]2+ photosensitizer, where bmip = 2,6-bis(3-methyl-imidazole-1-ylidine)-pyridine, with simultaneous femtosecond-resolution Fe Kα and Kβ X-ray em

The AIRE gene plays a key role in the development of central immune tolerance by promoting thymic presentation of tissue-specific molecules. Patients with AIRE-deficiency develop multiple autoimmune manifestations and display autoantibodies against the affected tissues. In 2016 it was reported that: i) the spectrum of autoantibodies in patients with AIRE-deficiency is much broader than previously

Med nya läkemedel, hudvårdsprodukter, stekpannor och bekämpningsmedel följer också att allt fler föroreningar släpps ut i naturen via bland annat jordbruk samt avlopp från industrier och sjukhus. Dessa föroreningar sprids till våra vattendrag, påverkar de organismer som lever där negativt och kan även förorena vårt dricksvatten. Ett läkemedel som släpps ut i naturen och som kan ses som särskilt pOrganic contaminants are present in aquatic environments and there is a need for water treatment techniques that are both efficient and practically implementable. Antibiotics are particularly problematic organic contaminants, as insufficient removal can contribute to the spread of antibiotic resistance, which can affect essential bacteria for ecosystems and cause untreatable infections in humans.

We explore vibe coding as a rapid prototyping approach powered by generative AI. We discuss how it lowers the barrier to creating high-fidelity prototypes, enabling nontechnical users to build apps, and examine its implications for communication, validation, and iterative software design.

The cumulative risk of NHL in Sweden by age 80 years has increased to 1.1 in women and 1.6% in men in 2011. Increased risk of non-Hodgkin lymphoma (NHL) associated with personal histories of some autoimmune diseases (ADs) are known. It is unclear whether there are other NHL-related ADs and whether this association holds across different sex, age and year of diagnosis, or NHL histological subtypes.

BACKGROUND: There is little consensus on a standard approach to analysing bone scan images. The Bone Scan Index (BSI) is predictive of survival in patients with progressive prostate cancer (PCa), but the popularity of this metric is hampered by the tedium of the manual calculation. OBJECTIVE: Develop a fully automated method of quantifying the BSI and determining the clinical value of automated

The integration of machine learning (ML) into software operations (MLOps) has significantly increased the demand for data to train and test models, making data sharing and reuse essential to mitigate the high costs of data collection and preprocessing. This study aims to advance the understanding of data sharing within an MLOps context by examining the establishment and governance of a data ecosys

This study explores the integration of Large Language Model (LLM) and Information Retrieval (IR) components to enable filtered search over multimodal structured data. We identify core integration challenges and introduce a conceptual framework based on two paradigms: filtered retrieval and filtered re-ranking. With the focus on the latter, we employ RT-3 rank transformation to dynamically adjust t

Objective: Although previous studies have shown reduced cardiovascular events following parathyroidectomy (PTX), it is unclear whether this extends to contemporary patients diagnosed and treated with milder disease than previously. The aim of this nation-wide study was to determine the effect on cardiovascular events after PTX, and to comprehensively evaluate cardiovascular disease manifestations

14 Utbildningsplan Musikerutbildning cembalo, 180 hp – kandidat 1. IDENTIFIKATION Programmets namn och inriktning: musikerutbildning, cembalo. Omfattning i högskolepoäng: 180. Nivå: Grundnivå (G). Programkod: KGMUS. Inriktning: CEMB. 2. BESLUTSUPPGIFTER Utbildningsplanen är reviderad och beslutad av konstnärliga fakul- tetsstyrelsen 2017-10-18. Den reviderade utbildningsplanen träder i kraft HT-17

https://www.mhm.lu.se/sites/mhm.lu.se/files/mu_utbildningsplaner_samlingsdokument_cembalo_kand.pdf - 2026-05-30