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As global warming is proceeding due to rising greenhouse gas concentrations, the Earth system moves towards climate states that challenge adaptation. Past Earth system states are offering possible modelling systems for the global warming of the coming decades. These include the climate of the mid-Pliocene (∼ 3 Ma), the last interglacial (∼ 129-116 ka) and the mid-Holocene (∼ 6 ka). The simulations
Massive multiple-input multiple-out (MIMO) technology is vital in millimeter-wave (mmWave) bands to obtain large array gains. However, there are practical challenges, such as high hardware cost and power consumption in such systems. A promising solution to these problems is to adopt a hybrid beamforming architecture. This architecture has a much lower number of transceiver (TRx) chains than the to
Using light scattering (LS), small-angle X-ray scattering (SAXS), and coarse-grained Monte Carlo (MC) simulations, we studied the self-interactions of two monoclonal antibodies (mAbs), PPI03 and PPI13. With LS measurements, we obtained the osmotic second virial coefficient, B22, and the molecular weight, Mw, of the two mAbs, while with SAXS measurements, we studied the mAbs' self-interaction behav
The osmotic pressure of dilute electrolyte solutions containing charged macro-ions as well as counterions can be computed directly from the particle distribution via the well-known cell model. Originally derived within the Poisson-Boltzmann mean-field approximation, the cell model considers a single macro-ion centered into a cell, together with counterions needed to neutralize the total cell charg
BackgroundDischarge from a neonatal care unit is often experienced as a vulnerable time for parents. By communicating through digital technology, it may be possible to improve the support for parents and thereby make the transition from hospital to home less stressful.AimTo develop an eHealth device supporting the transition from hospital to home for parents with a preterm‐born child in Sweden usi
Novel methods for the inference of radiation intensityfunctions defined over known surfaces are proposed, intendedfor use in surveying applications with mobile spectrometers.Previous approaches, based on the maximum likelihoodexpectation maximization (ML-EM) framework with Poissonlikelihoods, are extended to better handle spatially continuousintensity statistics using ideas from Gaussian filtering
Mobile communications have been undergoing a generational change every ten years or so. However, the time difference between the so-called "G's" is also decreasing. While fifth-generation (5G) systems are becoming a commercial reality, there is already significant interest in systems beyond 5G, which we refer to as the sixth-generation (6G) of wireless systems. In contrast to the already published
Intrinsically disordered proteins (IDPs) adopt heterogeneous conformational ensembles in solution. The properties of the conformational ensemble are dependent upon the solution conditions, including the presence of ions, temperature, and crowding, and often directly impact biological function. Many in vitro investigations focus on the properties of IDPs under dilute conditions, rather than the cro
The aethalometer model has shown to offer a fast, inexpensive and robust method for source apportionment. The method relies on aerosol light absorption attribution, mass balance of the total carbon and results in a fraction of unaccounted, residual carbon that has been associated to biogenic carbon due to its presumably non-light absorbing properties. This residual carbon and its relation to trace
It is tractable to increase the torque for an HCCI engine and one way is to add a turbocharger. Operating in HCCI mode requires accurate control of the combustion phasing, CA50. The higher the engine torque, the narrower the CA50 window becomes where HCCI operation is maintained. As the CA50 varies stochastically between cycles this requires improved CA50 control for turbo HCCI engines. The main f
The addition of polyelectrolytes (PEs) to suspensions of charged colloids, such as nanoplatelets (NPs), is of great interest due to their specific feature of being either a stabilizing or a destabilizing agent. Here, the complexation between a PE and oppositely charged NPs is studied utilizing coarse-grained molecular dynamics simulations based on the continuum model. The complex formation is eval
Smart contracts are programs with data (mutable state); stored on and executed by blockchain platforms. The transactions (or function invocations) dispatched to smart contracts often change their state. In the Ethereum blockchain, nodes (aka miners/validators) can schedule a set of transactions in any order in a block. Multiple transactions in a single block operating on a contract's shared state
Objective: The purpose of this paper is to identify the largest cognitive challenges faced by novices, developing software in teams, using distributed cognition as an observational filter.Paradigm: Design science Epistemology: Pragmatist Methodology: Case studyMethod: Using grounded theory, ethnography and multi method data collection, we conducted an observational study for two months following f
Microcontrollers have become an integral part of modern everyday embedded systems, such as smart bikes, cars, and drones. Typically, microcontrollers operate under real-time constraints, which require the timely execution of programs on the resource-constrained hardware. As embedded systems are becoming increasingly more complex, microcontrollers run the risk of violating their timing constraints,
This paper presents a stabilized scheme that solves the wave propagation problem in a general bianisotropic, stratified medium. The method utilizes the concept of propagators, i.e., the wave propagation operators that map the total tangential electric and magnetic fields from one plane in the slab to another. The scheme transforms the propagator approach into a scattering matrix form, where a spec
A co-designed (3+3)-port antenna for dual-band operation that requires no feeding or decoupling network is proposed and verified. The antenna consists of six ports which are divided into two groups that resonate in two differentfrequency ranges. The basic radiating element is a tri-modal patch in a folded snowflake-shaped structure with the largest antenna dimension of 0.48λ1 or 0.68λ2, where λ1 and
