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Brain-derived neurotrophic factor (BDNF) is involved in brain plasticity and neuronal survival. Generally, BDNF enhances synaptic activity and neurite growth, although the effect of BDNF on neuronal survival and brain plasticity following injury is equivocal. Housing rats in an enriched environment after experimental stroke enhances recovery of sensory-motor function, which is associated with a de
Streptococcus dysgalactiae subsp. equisimilis (group G streptococci; GGS) cause disease in humans but are often regarded as commensals in comparison with Streptococcus pyogenes (group A streptococci; GAS). The current study investigated the degree and kinetics of the innate immune response elicited by the two species. This was assessed as expression of the chemokine MIG/CXCL9 and bacterial suscept
Treatment of Mv1Lu mink lung epithelial cells with transforming growth factor-beta 1 (TGF-beta 1) prevents phosphorylation of the retinoblastoma susceptibility gene product, RB, in late G1 phase of the cell cycle, which is thought to retain RB in a growth-suppressive state. This effect is paralleled by cell cycle arrest in late G1 (M. Laiho, J. A. DeCapric, J. W. Ludlow, D. M. Livingston, and J. M
This study examines how public transport passengers experience and use travel time and under what conditions they are particularly concerned about shorter travel time. Using a survey of Swedish public transport users and a follow-up focus group, we compare current patterns with a similar 2009 study. Findings indicate a slight decline in perceived value of travel time, coinciding with a marked redu
Background: 5-Fluorouracil (5-FU) and the Folate Leucovorin (LV) form the chemotherapy backbone for metastatic colorectal cancer (mCRC). Tumoral expression of specific folate-associated genes is associated with the risk of recurrence in stage III CRC following adjuvant 5-FU/LV (FLV)-based combination chemotherapy according to the Nordic bolus regimen. The aim was to evaluate whether expression of
Pancreatic ductal adenocarcinoma has one of the worst survival rates among adult cancers, with only 11% in the United States surviving five years after diagnosis. The majority of patients are diagnosed with late-stage disease, since early-stage pancreatic ductal adenocarcinoma is typically either asymptomatic or presents with non-specific symptoms. Pancreatic ductal adenocarcinoma thus remains a h
This study examines whether unstructured and structured activities interact in their association with delinquency and cannabis use. We hypothesize that unstructured activities are more strongly associated with delinquency and cannabis use for those who are less engaged in structured activities. Data are drawn from three nationally representative self-report studies conducted between 2005 and 2011
Fibulin-1, a circulating extracellular matrix glycoprotein, has been associated with arterial disease and elevated N-terminal prohormone B-type natriuretic peptide (NT-proBNP) in diabetes. Soluble urokinase plasminogen activator receptor (suPAR), a marker of inflammation, has been associated with subclinical atherosclerosis. Therefore, we aimed to explore the interplay between these biomarkers and
Both development practice and research have paid attention to the issue of sexual and gender-based violence in armed conflict in recent years. However, feminist scholars criticise policies on the issue for reproducing the gendered power relations which are at the root of violence. Research focuses on the policies of a few prominent donors, while policies of lesser-known actors have hardly been exa
We present a detailed comparison of ectopic ossification (EO) found in tendons of biglycan (Bgn), fibromodulin (Fmod) single and double Bgn/Fmod-deficient (DKO) mice with aging. At 3 months, Fmod KO, Bgn KO and DKO displayed torn cruciate ligaments and EO in their quadriceps tendon, menisci and cruciate and patellar ligaments. The phenotype was the least severe in the Fmod KO, intermediate in the
För att nå långsiktig framgång måste företag röra sig snabbare och anpassa sig bättre till omgivningen än sina konkurrenter. Ett sätt att göra detta är att ta del av innovati-va teknologier för att skapa konkurrensfördelar. Nowaste Logistics som är en tredje-partsleverantör inom frukt och grönsaksmarknaden, beslutade år 2008 att införa RFID-teknologi för att öka spårbarheten på sina varor och på s
In this paper I review the current body of knowledge linking entrepreneurial motivation and performance. From this frame of reference I evaluate my experiences in commercialization of university research within the context of the entrepreneurship program. Commercialization of university research and external ideas has been a major priority of program. The students are strongly encouraged to develo
The link between the incurrence of a customs debt and the incurrence of the Value Added Tax on importation, have a parallel nature, as they arise from the importation of goods into the territory of the Community. This link is a result of Article 71 (1) of the VAT Directive. This article authorises member states to link the chargeable event and the chargeability of VAT on importation of goods with
Original/Value: This paper contributes to the narrow body of research on a complex phenomenon: brand activism and customers’ perception. It presents a new framework for analysing the relationship between the brand vision and brand image. Furthermore, it compares and contrasts the brand activism of two different fashion companies.
