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Treatment With Reduced-Dose Trimethoprim-Sulfamethoxazole Is Effective in Mild to Moderate Pneumocystis jirovecii Pneumonia in Patients With Hematologic Malignancies

BACKGROUND: Recent studies have reported that reduced-dose trimethoprim-sulfamethoxazole (TMP-SMX) may be effective in the treatment of Pneumocystis jirovecii pneumonia (PJP), but data are lacking for patients with hematologic malignancies.METHODS: This retrospective study included all adult hematologic patients with PJP between 2013 and 2017 at 6 Swedish university hospitals. Treatment with 7.5-1

Learning with Skill-based Robot Systems : Combining Planning & Knowledge Representation with Reinforcement Learning

The usage of robots in industry is transforming. Traditionally, robots have been deployed to automate monotonous tasks through manual programming, excelling in speed and precision yet lacking flexibility. Now, as part of Industry 4.0, the paradigm is shifting towards collaborative robotics, where robots are expected to interact dynamically with their environment and handle non-repetitive tasks. Th

Simulations of7Be and10Be with the GEOS-Chem global model v14.0.2 using state-of-The-Art production rates

The cosmogenic radionuclides 7Be and 10Be are useful tracers for atmospheric transport studies. Combining 7Be and 10Be measurements with an atmospheric transport model can not only improve our understanding of the radionuclide transport and deposition processes but also provide an evaluation of the transport process in the model. To simulate these aerosol tracers, it is critical to evaluate the in

Modeling Atmospheric Transport of Cosmogenic Radionuclide 10Be Using GEOS-Chem 14.1.1 and ECHAM6.3-HAM2.3 : Implications for Solar and Geomagnetic Reconstructions

A prerequisite to applying 10Be in natural archives for solar and geomagnetic reconstructions is to know how 10Be deposition reflects atmospheric production changes. However, this relationship remains debated. To address this, we use two state-of-the-art global models GEOS-Chem and ECHAM6.3-HAM2.3 with the latest beryllium production model. During solar modulation, both models suggest that 10Be de

Solar, Atmospheric, and Volcanic Impacts on 10Be Depositions in Greenland and Antarctica During the Last 100 Years

Cosmogenic radionuclides (e.g., 10Be) from ice cores are a powerful tool for solar reconstructions back in time. However, superimposed on the solar signal, other factors like weather/climate and volcanic influences on 10Be can complicate the interpretation of 10Be data. A comprehensive study of 10Be records over the recent period, when atmospheric 10Be production and meteorological conditions are

Navigating the upcoming European Union AI act

The upcoming Artificial Intelligence (AI) Act is the European Union's attempt to regulate high-risk AI systems and foundation models. We give an up-to-date overview of the act's key requirements, explain how the high-risk classification works, and highlight what matters for its operationalization.

Efficient Demand Evaluation of Fixed-Point Attributes using Static Analysis

Declarative approaches to program analysis promise a number of practical advantages over imperative approaches, from eliminating manual worklist management to increasing modularity. Reference Attribute Grammars (RAGs) are one such approach. One particular advantage of RAGs is the automatic generation of on-demand implementations, suitable for query-based interactive tooling as well as for client a

Survey of gender bias in the IPCC

The Intergovernmental Panel on Climate Change needs to do more to include the expertise and voices of women, even as numbers and policies improve.

The Cloudy Nature of Aerosols : Portrayed by the modelled and observed atmosphere

For decades, the environmental sciences have engaged in measuring and modelling natural systems to increase our understanding and prediction of climate change. This thesis advances these efforts by analyzing and applying in-situ instruments, remote sensing, and modelling approaches. The main focus lies in utilizing a state-of-the-art global Earth System Model (ESM) EC-Earth3, which is used to simu

The perceived innovativeness of the manufacturing process and perceived product quality. The case of creative and technology-intensive industries.

Title: The perceived innovativeness of the manufacturing process and perceived product quality. The case of creative and technology-intensive industries. Course: BUSN39 Degree Project in Global Marketing Authors: Federica Piccone & Joanna Pilawa Supervisor: Javier Cenamor Keywords: manufacturing process; perceived innovativeness; perceived quality Thesis Purpose: The main purpose is to

A digital tool for mathematical calculations with focus on interaction design

Efterfrågan av digitala verktyg i skolor har ökat de senaste åren och idag är det enligt Skolverket ett krav att använda digitala verktyg i matematik. Digitala matematiska verktyg kan förse elever med automatisk återkoppling och lärare kan anpassa sitt sätt att undervisa, baserat på elevernas progression. Trots att det finns flera fördelar med att inkludera digitala matematiska verktyg, finns det The demand for digital tools in schools has increased over the years and today it is a requirement from the Swedish National Agency for Education to use digital tools in mathematics. Digital mathematical tools can provide students with automated feedback and teachers can adapt their teaching strategy based on data from their students’ progress. Even though there are multiple advantages of includin

Åtalsunderlåtelse i konkurrensfall

The primary rule of absolute duty to prosecute is stated in 20:6 RB. This means that the prosecutor is obliged to engage prosecution when there is sufficient evidence for a conviction. The possibility of waiver of prosecution is stated in 20:7 RB and is an exception from the absolute duty of prosecution. The prosecutor can decide to waive prosecution for minor offense not resulting in any other pe

Kundbvärde i agila projekt

Agile methods have the recent years gained ground within the software industry by being lean and flexible, and one of the companies having adopted agile methods is the fast‐growing Swedish developer of mobile applications Tactel AB. The company was interested in enhanced knowledge within the agile area, specifically about Scrum, and with one of its development teams – Mobical – in focus, Tactel wa

How production offshoring impacts process innovation in the home country

This thesis investigates how offshoring influences process innovation in the home country. This topic, although stimulating, has been understudied in the past by academia. I have elaborated two innovative hypotheses according to which relocations would hurt process innovation in the home country because 1) they are used as an alternative to process innovation, and 2) they damage trade-unions. To e

Three can keep a secret if two are dead - En fallstudie av Hells Angels kontraspionage

This study investigated the counterintelligence activities of a criminal organisation – Hells Angels. The evolution of counterintelligence skills can be understood as a learning process in which Hells Angels adapts its counterintelligence activities as authorities adopt new methods and techniques. The study set out to answer the questions of 1) how Hells Angels responded to authorities´ efforts to

Requirements on technical debt : dare to specify them!

Could maintainability requirements help organizations prioritize technical debt management? The new standard ISO/IEC 5055 Automated Source Code Quality Measures can be used to set targets. We also look at a pragmatic way to turn CodeScene’s code health metric into a quality gate for pull requests.

Requirements engineering and large language models : insights from a panel

As a general-purpose technology, large language models promise to enhance various software engineering tasks. But how will they impact requirements engineering? This column offers a summary of an expert panel discussion from the 2023 International Requirements Engineering Conference in Hanover, Germany.

Communication and use of climate scenarios for climate change adaptation in Finland, Sweden and Norway

This paper assesses the communication and the use of climate scenarios at the science–science and science–policy interface in Finland, Sweden and Norway. It is based on document analysis and stakeholder questionnaires. The questionnaires targeted three stakeholder groups, all engaged in the communication and the use of climate scenario information: climate scenario producers; impact, adaptation an

Climate benefits of Nordic forestry revisited, a review

Forests and forestry are relevant for multiple uses and benefits. The increasing urgency of climate change warrants consideration of how to balance use of forests as a carbon sink and use of wood for products. Carbon sink benefits are recognized in climate science, international climate policy, and also integrated into, e.g. the EU’s climate mitigation pathways. Climate benefits of forest products