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Background. Seeking to clarify the parent-offspring transmission of Major Depression (MD) and type I Bipolar Disorder (BD), we examined offspring MD and BD risk in five informative parental pairs: Unaffected x MD, Unaffected x BD, MDxMD, MDxBD and BDxBD. Methods. We identified 289,637 individuals born in Sweden 1970-1990, followed through 2018, from parents with MD and/or BD identified from Swedis
Abstract is not available.
The implementation of new surgical techniques offers chances but carries risks. Usually, several years pass before a critical appraisal and a balanced opinion of a new treatment method are available and rely on the evidence from the literature and expert's opinion. The frozen elephant trunk (FET) technique has been increasingly used to treat complex pathologies of the aortic arch and the descendin
A complete census of planetary systems around a volume-limited sample of solar-type stars (FGK dwarfs) in the Solar neighborhood (d a parts per thousand currency signaEuro parts per thousand 15 pc) with uniform sensitivity down to Earth-mass planets within their Habitable Zones out to several AUs would be a major milestone in extrasolar planets astrophysics. This fundamental goal can be achieved w
It is clinically important to estimate the size of a myocardial infarction (MI) to predict patient prognosis, to determine the ability of a therapy to limit its size, and to evaluate its effect on left ventricular function. Various electrocardiographic methods have been used for these purposes but their accuracies have not been compared with each other using an identical reference population of an
Human embryonic stern cells (hESC) are now routinely cultured in many laboratories, and differentiation protocols are available to generate a large variety of cell types. In all ongoing ethical debate opinions of different groups are based oil varying sets of religious, historical, cultural and scientific arguments as well as oil widely differing levels of general information. We here give all ove
The current fire testing and classification system and corresponding tests is mainly based on prescriptive building fire codes. This has certain limitations resulting in restricting the possible use of these tests for performance-based design within fire safety engineering (FSE). It also restricts innovation and cost-efficiency for companies supplying materials/components for buildings and transpo
MAX IV is presently under construction at Lund, Sweden, and the first beam for the production of synchrotron radiation is expected to circulate in 2016. The whole set of 3 GeV ring beam pipes is coated with Ti-Zr-V Non Evaporable Getter (NEG) thin film in order to fulfil the average pressure requirement of 1×10-9 mbar, despite the compact magnet layout and the large aspect ratio of the vacuum cham
Haemophilia A is a congenital bleeding disorder characterised by recurrent haemorrhages into the major joints. Haemophilic arthropathy is a well-established outcome of recurrent joint bleeding; however, it is clear that multiple factors determine the extent and severity of its occurrence. We sought to identify genetic factors related to abnormalities in range of motion (ROM) in the knees, ankles a
The detailed heat transfer distributions and pressure drop in the turn region of a U-bend channel with and without ribs have been experimentally investigated using liquid crystal thermography. The Reynolds numbers based on hydraulic diameter of the channel and the bulk velocity are 20,000 and 26,000. The ribs are mounted on the outer wall surface in the turn region of the U-bend channel; the rib h
Smoking is the main risk factor for COPD (chronic obstructive pulmonary disease) but genetic factors are of importance, since only a subset of smokers develops the disease. Sex differences have been suggested both in disease prevalence and response to environmental exposures. Furthermore, it has been shown that acquisition of 'addiction' to smoking is partly genetically mediated. Disease cases and
In the Prince Charles Mountains (PCMs) the conformable Permian-Triassic (P-T) succession is characterised by an abrupt transition from coal-bearing to coal-lacking strata, which coincides with the demise of the Permian Glossopteris-dominated flora. About 32% of the typical Permian spores and pollen are registered for the last time in the uppermost coal. Throughout the earliest Triassic an addition
In 2016, a national policy package consisting of six support measures was legislated and clarified in the Swedish school law. The six support measures aim to create clarity and guidance for teachers, principals and other relevant actors to integrate newly arrived children and youth and ensure they achieve the national curriculum requirements. Recent reports state that the gap between native an
Energy sufficiency has been recognised as a strategy to promote sustainable energy use and achieve climate neutrality. It aims to reduce energy demand in absolute terms. ‘Living Space Reduction’ (LSR) is one way to achieve energy sufficiency in the housing sector. However, existing studies highlight significant barriers to its materialisation, including the lack of funding and expert knowledge of
