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3,4-Dihydroxyphenyl-(L)-alanine ((L)-DOPA)-induced dyskinesia is associated with molecular and synaptic plasticity in the basal ganglia, but the occurrence of structural remodeling through cell genesis has not been explored. In this study, rats with 6-hydroxydopamine lesions received injections of the thymidine analog 5-bromo-2'-deoxyuridine (BrdU) concomitantly with (L)-DOPA for 2 weeks. A large
BACKGROUND: To describe the frequency, in some European populations, of the World Health Organisation (WHO) defined metabolic syndrome and to compare the frequency of this syndrome with an alternative definition for non-diabetic subjects, called the insulin resistance syndrome proposed by the European Group for the Study of Insulin Resistance (EGIR). METHODS: Investigators of eight European studie
We have examined the ability of KW-6002, an adenosine A2a antagonist, to modulate the dyskinetic effects of l-DOPA in 6-hydroxydopamine-lesioned rats. In animals rendered dyskinetic by a previous course of l-DOPA treatment, KW-6002 did not elicit any abnormal involuntary movements on its own, but failed to reduce the severity of dyskinesia when coadministered with l-DOPA. A second experiment was u
Popular Abstract in Swedish I den här doktorsavhandlingen presenteras ett datorprogram som utvecklats för att simulera och utvärdera biotekniska processer, där flera processteg kan vara integrerade. Speciellt har en process för framställning av mjölksyra från vetemjöl studerats. Mjölksyra har traditionellt använts i kemi-, läkemedels- och livsmedelsindustrin som t.ex. råvara, surgörare eller konseBiotechnical processes are often integrated to increase productivity and yield. It is difficult to predict the effects of process integration and to find optimum conditions for the process. A valuable tool for the evaluation of a complete process is mathematical modelling. In this thesis, a computer program developed for simulation and optimisation of integrated biotechnical processes is presented
The combination of visual art and music has resulted in many innovative audio-visual phenomena and provides an on-going exciting avenue of artistic production. This thesis explores one such phenomenon, the visual album. The visual album is a hybrid medium between music video and film; like music video, it promotes an audio album, and like film, it is conceived as a whole work of art. The visual al
This thesis aims to use an approach based upon image-based 3D modeling in a comparative analysis of maquetas and ceremonial structures from the Late Moche Period in the Jequetepeque Valley, Peru, and determine if this approach is constructive in such an analyses. During this work, one particular case will be used, comparing one maqueta from San José de Moro to one ceremonial structure of San Ildef
Nighttime satellite photographs of Earth reveal the location of lighting and provide a unique and highly accurate view of human settlement, density and distribution. Nighttime lights have been shown to correlate with economic development and population worldwide. Little research has been done on the link between nighttime lights and population change over time. This link is explored here for Europ
Abstract Sexual selection is considered to be one of the most important processes influencing the evolution and diversification of species. Sexual conflict, a subset of sexual selection theory, describes how opposing interests in the male and female reproductive systems can lead to one sex increasing its fitness at a cost to the other sex. Traits involved in this conflict may come under selection
High-pressure metamorphism and deformation of the Ullared Deformation Zone (UDZ) in the Eastern segment of the Sveconorwegian Orogen, southwest Sweden is evidenced by ~ 970 Ma retro-eclogite found in association with upper amphibolite and high-pressure granulite facies rocks. Petrographic, structural and geochronological studies of the UDZ were carried out to better understand the regional metamor
Broad public contention against nuclear energy can be observed as a new phenomenon in Japanese society after the 2011 Fukushima Daiichi nuclear power plant accident. This study aimed to detect an ample explanation about why the emergence of such a protest movement did only occur after the direct experience of a critical event and did not happen before. Discrediting a sole and simple grievance-base
Situated in a polarized debate on prostitution and sex work, this thesis sets out to explore the characteristics of the Sex Workers Rights Movement in a contemporary Danish context. The thesis builds on respectively a critical theoretical and a social constructivist epistemology. It identifies two main opposing approaches to prostitution and sex work in respectably an “anti-prostitution-” and a “p
Men are more interested in a researcher career than women, and awareness about the gender imbalance within the Academia increases men's interest (Tellhed, 2013). This study aimed to examine what causes the increase in men's interest and impairments in women's interest towards a researcher career. Two hundred and eight (99 males, 109 females) students received information about the Acad
Most countries engage in a wide variety of export promotion activities that provide domestic firms with significant support in the hopes of increasing trade volumes. The aim of this thesis is to examine one type of official Swedish export promotion, namely state visits. I investigate the potential effect of state visits, performed by Sweden’s head of state King Carl XVI Gustaf, on Swedish aggregat
The aim of this study is to critically explore the effects of pre-existing gender norms on the use of sexual and gender-based violence (SGBV) in the conflict in eastern Democratic Republic of Congo (DRC), and the normalization of such violence by examining the links between peacetime and wartime sexual violence. The analysis is based on a research overview that highlights aspects of gender, violen
Argentina is a country enriched with an abundance of natural resources. This great wealth of primary commodity goods has turned the region into one of the world’s most prominent exporters of agricultural goods like soybeans, wheat and oil. However, there is more to the story than just milk and honey. In light of the fluctuating nature of primary commodity prices, countries with high primary commod
This study examines possibility of positive contribution of population aging to enrolment ratios in tertiary education of 32 OECD countries from 1970 onward. It estimates an equation with fertility, life expectancy, GDP per capita, schooling age population for tertiary education and expenditures to education. In the equation, the variables reflect demand, supply and constraints on education identi
Misaligned strategies that are developed within different units in a company is unfortunately a common occurrence. Generally, operations strategy and marketing strategy are difficult to align; the operations unit and the sales unit often have troubles understanding each other. If adding a capacity planning perspective to this issue, it is obvious that the two units need a full understanding for ea
