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SummaryWe describe the collection of cohorts together with the analysis plan for an update of the fracture risk prediction tool FRAX with respect to current and novel risk factors. The resource comprises 2,138,428 participants with a follow-up of approximately 20 million person-years and 116,117 documented incident major osteoporotic fractures.IntroductionThe availability of the fracture risk asse
Background: Amyloid-beta (Aβ) is hypothesized to facilitate the spread of tau pathology beyond the medial temporal lobe (MTL). However, there is evidence that age-related Aβ-independent tau pathology is present outside the MTL (Kaufman et al., Acta Neuropathol, 2018). We examine tau deposition determined by positron emission tomography (PET) in regions typically involved earlier/later in AD and do
Organizations grow and excel with knowledge sharing; on the other hand, knowledge hiding is a negative behavior that impedes innovation, growth, problem solving, and timely correct decision making in organizations. It becomes more critical in the case of teaching hospitals, where, besides patient care, medical students are taught and trained. We assume that negative emotions lead employees to hide
This paper reports on a case study of a quadrilingual child, Stefan, born and raised in Sweden and exposed to four languages before his first birthday: English, French, Russian and Swedish. We examine his vocabularies in these languages by the Cross-Linguistic Lexical Tasks (Haman, Łuniewska, & Pomiechowska, 2015), designed to measure vocabulary in monolingual and multilingual children. Stefan
Hypothesis: Self-assembly of amphipathic styrene maleic acid copolymers with phospholipids in aqueous solution results in the formation of ‘nanodiscs’ containing a planar segment of phospholipid bilayer encapsulated by a polymer belt. Recently, studies have reported that lipids rapidly exchange between both nanodiscs in solution and external sources of lipids. Outstanding questions remain regardin
Expectations on collaboration between public authorities and civil society organizations (CSOs) have increased in Sweden the past decades, partly due to changes in the organization of welfare services. This article investigates a collaborative project within the migrant integration policy area. It is a collaboration between the employment offices in a region of Sweden and local CSOs with the commo
Health care currently constitute one of the largest parts of the Scandinavian welfare system, with private as well as public providers competing on a quasi-market. In order to ensure an egalitarian and safe provision of health care services this sector is governed by several policies, laws and regulations. Previous research demonstrates that these services are regulated by processes of decommodifi
Background: Emerging evidence indicates that gut inflammatory and immune response play a key role in the pathophysiology of stroke and may become a promising therapeutic target. However, the specific role of the microbiota-gut-brain axis in poststroke aphasia (PSA) patients remains unclear. Objectives: The aim of this study was to investigate the relationships among the gut microbiota, neuroendocr
Objective Giant cell arteritis (GCA) is a systemic disease with variable vascular involvement. The objective was to investigate predictors of time-dependent large-vessel involvement (LVI) in a population-based cohort of patients with GCA. Methods GCA patients with positive temporal artery biopsies (TAB) between 1997- 2010 were identified through a regional pathology register. A structured review o
This essay highlights the increasingly important role of city marketing in urban renewal. In particular, it focuses on the way that discourses in city marketing can impact the social geography of the city. In light of the urban renewal project H+, this thesis examines Helsingborg´s city marketing. The marketing of the project is analyzed through critical discourse analysis, drawing upon the theore
In recent years, Ethiopia’s double-digit growth rates are regarded as an economic miracle. As the government assigned a key role for the private sector to promote industrialization, this paper investigates the current state of the private sector in the manufacturing industry and the extent it contributes to the growth and development in Ethiopia. An exploratory case study approach was implemented
Utsläpp av växthusgaser sedan mitten av 1800-talet har orsakat klimatförändring som bland annat leder till en ökning av både avsmältning i kryosfären och värmeutvidgning i haven, två faktorer som gjort att havsnivån stigit allt snabbare under det senaste århundradet. Havsnivåhöjning kan öka förekomsten av översvämningar av land, vägar och järnvägar samt påverka miljöobjekt, och på grund av detta iThis study uses GIS analyses to investigate the risk that increasing sea levels and highest projected highwater pose by increasing the risk of inundation on state-owned roads and railways as well as environmental objects in their side areas. This is done through an assessment of sea level rise projections and a risk analysis, which points out where vulnerable features are located and provides time
Processing of personal data encompasses any operation performed on personal data. Nowadays, processing is increasingly done by automated or autonomous means thanks to the emergence of new technologies such as algorithms, machine learning (ML) and artificial intelligence (AI). This is not surprising, considering that application of these technologies provides many benefits for organisations, such a
Public transport and health care constitute the top two priorities for regional authorities in Sweden. Being cost-efficient in the execution of these services is important, not only to lower the costs but also to reach maximum social benefits for the available funding. In sectors like these, where the value of what is produced is not solely measured through the consumers’ willingness to pay, maxim
Background Kenya is facing social and economic problems related to the high unemployment rate the country has suffered since independence. The Kenyan government are placing a lot, if not all, eggs in one basket and betting on entrepreneurship to solve these problem. For entrepreneurship to thrive there needs to be an ecosystem facilitating it and inherent in this ecosystem are support organisation
Endowed with diverse vegetation covers, the Middle Atlas Mountains receive substantial snowfall in winter, which contributes to plant hydration during the growing season. Using remotely-sensed imagery, this study aims to assess the trends in snow cover variations between 2000 and 2015, analyse the local influence of snowpack persistence on vegetation growth and evaluate the significance of this ef
Climate change is a global and demanding issue, which affects all the states on the planet. The European Union has from the 90s been vigorously engaged in the international efforts to tackle climate change and even pursued to take on the leading role in the global climate regime. The two most anticipated UN conferences for combating climate change at the global level were the COP15 in 2009 and COP
We present the first study of the year-round distribution, activity patterns, and habitat use of one of New Zealand’s most common seabirds, the fluttering shearwater (Puffinus gavia). Seven individuals from Burgess Island and one individual from Long Island were successfully tracked with combined light-saltwater immersion loggers for one to three years. Our tracking data confirms that fluttering s
In the initial stage of planning, considering the solar impact of urban layout on the building can effectively avoid some irreversible design issues, improve the indoor environment, and reduce energy demand. The typical architectural models of three representative cities (Copenhagen, Berlin and Hong Kong) were selected as the analysis cases in this study. By analysing several sunlight and solar me
