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Aims: Estimation of prognosis in pulmonary arterial hypertension (PAH) has been influenced by that various risk stratification models use different numbers of prognostic parameters, as well as the lack of a comprehensive and time-saving risk assessment calculator. We therefore evaluated the various European Society of Cardiology (ESC)-/European Respiratory Society (ERS)-based three-and four-strata
The thesis concerns glycosyl transfer with use of b-glycosidases, most of them from hyperthermophilic organisms. Both optimisation of the reaction conditions and protein engineering in terms of site-directed mutagenesis were used to improve b-glycosidase-catalysed reactions. The first part of the work deals with conversion of lactose into valuable products such as galacto-oligosaccharides (GOS) an
An important traffic engineering problem for OSPF networks is the determination of optimal link weights. Certainly, this depends on the traffic engineering objective. Regardless, often a variety of performance measures may be of interest to a network provider due to their impact on the network. In this paper, we consider different objectives and discuss how they impact the determination of the lin
Salinisation is a global issue which leads to desertification and soil degradation and exposure to salt is also known to inhibit microbial activity and plant growth. This study was conducted to determine the influence of salinity on microbial activity of a non- saline soil. By using Salt Induced Community Tolerance (SICT) concept I found that microbial community tolerance to salt can be induced in
Problemområde: Situationen på take-awaymarknaden i Sverige i relation till de möjligheter som finns för att utveckla denna i framtiden. För uppsatsen tas en utgångspunkt i följande generella frågeställningar: 1. Vilka teoretiska utgångspunkter finns för fenomenet? 2. Hur har fenomenet utvecklats och hur tar det sig uttryck idag? 3. Varför och hur arbetar företag med fenomenet? 4. Varför och hur ef
Abstract Uppsatsen Fienden Inifrån granskar medierapporteringen kring Anders Breivik – gärningsmannen bakom terrordåden i Oslo den 22 juli 2011 med syftet att nå djupare insikt i hur media konstruerar fienden när denne kommer inifrån det egna samhället, samt vilka konsekvenser denna konstruktion får. Genom att undersöka 16 artiklar publicerade i Dagens Nyheter analyseras mediekonstruktionen av fi
This report evaluates and compares the methods in fire inspection at Malmø Fire Brigade and Copenhagen Fire Brigade. The report also examines fire safety laws and regulations and the educational differences of the fire inspectors in Malmø and Copenhagen. The investigation is a project for Malmø Fire Brigade and Copenhagen Fire Brigade in co-operation with the Department of Fire Safety Engineering
The exhaustion doctrine (also known in some jurisdictions as the ''first sale doctrine See U.S. Copyright Code Section 109(a)'') is one of the basic rules of intellectual property (IP) system, and is applied to many IP rights, from copyright to trademark. The term ''exhaustion'' or ''first sale'' describes the concept of this rule, where, after the &
Vid en diskussion om nivån på den svenska bolagsskatten är det av stor vikt att avgöra huruvida diskussionen rör den nominella eller den effektiva skattesatsen. Den nominella skattesatsen uppgår till 28 procent och återfinns i 65 kap. 14 § IL. Den effektiva skattesatsen är däremot inte given utan kan i viss utsträckning påverkas, eftersom den bestäms genom att dividera skatt på årets resultat med
PURPOSE: The systolic blood pressure (SBP) response to exercise reflects cardiovascular health, with both exaggerated and blunted responses linked to adverse outcomes. Prior studies relied typically on peak SBP or two-point slopes for evaluation. We aimed to identify distinct SBP responses from full times-series recorded during maximal, graded exercise and assess their clinical determinants and pr
This thesis encompasses an introductory part and five papers related to developing techniques and phantoms required for the further growth of photoacoustic imaging (PAI). In PAI, images are created by detecting acoustic waves followed by the absorption of laser light, enabling high spatial resolution while maintaining high optical contrast. Due to the distinct absorption patterns of various chromo
Human-bacterial interactions play a crucial role in several essential aspects of life. Here, we describe how a secreted protein from the skin commensal Cutibacterium acnes, RoxP, functions as a sacrificial redox effector molecule that facilitates beneficial interactions with its human host by counteracting oxidative stress and reducing stress-induced inflammation. Using a combination of structural
The European spruce bark beetle is considered as one of the most destructive forest insects to Norway spruce trees in Europe. Climate change may increase the frequency and intensity of bark beetle outbreaks. It is therefore of vital importance to detect the bark beetle outbreaks and take it under control to prevent further damages. Remote sensing techniques may provide a cost-efficient solution to
Background Diabetes has been defined on the basis of different biomarkers, including fasting plasma glucose (FPG), 2-h plasma glucose in an oral glucose tolerance test (2hOGTT), and HbA(1c). We assessed the effect of different diagnostic definitions on both the population prevalence of diabetes and the classification of previously undiagnosed individuals as having diabetes versus not having diabet
Under hösten 2012 och vintern 2013 ansvarade Stefan Larsson och Per Runeson för en tvärvetenskaplig studiegrupp om Det digitala samhället på Pufendorfinstitutet vid Lunds universitet. Vid sex seminarietillfällen under hösten 2012 och början av 2013 träffades 17 forskare från sex fakulteter, en eftermiddag, var tredje vecka för att få olika perspektiv att mötas och konfronteras kring aspekter på de
A matched filter composed of a time lagged feedforward artificial neural Network (TLFN) and a pulse-shaping filter is used in a noisy environment to detect R-waves for pacemakers. The TLFN reduces the influence of lower frequencies in the invasive electrogram (EGM) signals, e.g. P and T waves, and conditions the EGM to optimize the performance of the dynamically updated matched filter. Detector pe
Objectives: The aim of this study was to evaluate the efficacy of the natural antioxidant astaxanthin in functional dyspepsia in different doses and compared with placebo. Design: The study was a controlled, prospective, randomized, and double blind trial. Participants: Patients with functional dyspepsia, divided into three groups with 44 individuals in each group (placebo, 16 mg, or 40 mg astaxan
Background: The aim of this study is to estimate ovarian volume, number and volume of antral follicles, and ovarian power Doppler vascular indices as assessed by three-dimensional (3D) transvaginal grayscale and power Doppler ultrasound in women using combined oral contraceptives (COC). Study Design: Two hundred thirteen gynecologically asymptomatic women 20-39 years old using COC were examined wi
