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Background: The Implantable Cardioverter-Defibrillator (ICD) is a well-established life-saving therapy for heart failure patients, but due to the risk for unnecessary shocks, deactivation of ICD:s is recommended at the end of life. We aimed to identify i) how many people with HF and an ICD who died in Sweden in 2018 received Specialized Palliative Care (SPC), ii) of those dying outside of hospital

Background and PurposeIn a previous study comparing the amount of visual field damage at presentation in patients having open-angle glaucoma (OAG) identified through screening and in patients diagnosed in routine clinical practice in the 1990s, the damage was considerably worse in the clinically diagnosed patients. In the present study we compare visual field damage at presentation in the same 402

As 6G networks evolve, offloading extended reality (XR) applications emerges as a key use case, leveraging reduced latency and edge processing to migrate computationally intensive tasks, such as rendering, from user devices to the network. This enables lower battery consumption and smaller device form factors in cellular environments.However, offloading incurs delays from network transmission and

Purpose: Cancer affects a great number of people during working life, and tailored interventions targeting this population are important. The present study, focused on the developmental phase of a work-oriented intervention, aimed to describe work-related experiences and needs among people undergoing curative cancer therapy. Methods: People (n = 22, age md 55 years, range 39–64, purposive sampling

Introduction. The fourth edition of the Transatlantic Orthopedic Surgery Webinar 2022 took place on December 12th, 2022. The main theme of the webinar was the treatment of crouch gait in children with cerebral palsy (CP). Speakers from Australia, Canada, China, Germany, India, Poland, Spain, Sweden, Turkey, the United Kingdom, and the United States participated. Results. The first general session

Wages earned by men are often used as an indicator of the material standard of living (MSoL). However, this indicator relies on several assumptions when used for comparisons across time and space. Considering these assumptions will improve estimates of the MSoL from wages. One necessary assumption is that households in the compared populations relied on the primary income of the male head of house

Aerosol-cloud interactions (ACI) are a major source of uncertainty in climate science, critically affecting our ability to project near-term climate evolution and assess societal risks. These interactions influence effective radiative forcing, cloud dynamics, and precipitation patterns, yet remain insufficiently constrained due to limitations in observations, modeling, and process understanding. T

AIMS: To build a comprehensive biobank integrated in the Swedish Heart Failure Registry (SwedeHF) comprising comprehensive clinomic data, proteomic, transcriptomic and genomic information in combination with clinical and diagnostic characteristics and additional ICD-code registry data.METHODS: Blood and urine samples will be biobanked at SwedeHF registration with an optional second sampling after

SLAM is one of the biggest bottlenecks of XR devices, which have strict requirements for latency, power consumption, and user satisfaction. A solution that has been proposed and studied to meet the requirements is to offload SLAM to a remote server, which leverages computational hardware but may suffer due to incurred delays and transmission power. In this work, we propose offloading SLAM using Ma

Although variations in temperature have a profound impact on cardiac function, little is known regarding the excitation and contractile parameters over a broad temperature interval. In view of the clinical implications of lowered temperature in resuscitation and in cardiac preservation/evaluation for transplantation, we have examined the contractile function using Langendorff perfused hearts and i

The Hu Huanyong Line (Hu Line) shows an uneven geographical pattern of urbanization between Southeast and Northwest China. Based on three questions proposed by the Chinese Premier, the balance of urbanization on both sides of the Hu Line and the possibility of breaking through the pattern in the future has provoked substantial interest in academic circles. Based on quantitative analyses and urban

Many seriously ill and frail older people experience a lack of practical support and meaningful social engagement. While healthcare provides good medical support, it lacks the full competence and resources to help with social, practical and existential challenges that can arise near the end-of-life. Increasingly, resources in civil society are enlisted to fill this care gap. One such attempt to br

Introduction: Moral distress arises when healthcare workers face difficult decisions without adequate information and/or when patient care is compromised due to limited resources, communication issues, or altered work routines in exceptional circumstances. While moral distress in maternity and neonatal healthcare workers (MNHCWs) has been noted, its prevalence, intensity, and impact on well-being

Release of halide ions is an essential step of the catalytic cycle of haloalkane dehalogenases. Here we describe experimentally and computationally the process of release of a halide anion from the buried active site of the haloalkane dehalogenase LinB. Using stopped-flow fluorescence analysis and umbrella sampling free energy calculations, we show that the anion binding is ion-specific and follow

Code review is a well-established and valued practice in the software engineering community contributing to both code quality and interpersonal benefits. However, there are challenges in both tools and processes that give rise to misalignments and frustrations. Recent research seeks to address this by automating code review entirely, but we believe that this risks losing the majority of the interp

BACKGROUND: Atrial fibrillation (AF) is suggested to be associated with venous thromboembolism (VTE) and might thereby play a role in the development of chronic thromboembolic pulmonary hypertension (PH). By elevating left-sided filling pressure and promoting atrial myopathy, AF may also play a role in the development of postcapillary PH. We aimed to investigate the association between AF, with or