Search results

In recent years the possibility to increase maximum length and weight of heavy goods vehicles to allow for High Capacity Vehicles (HCVs) has been debated in Sweden. Proposals to increase maximum weight to 74 tonnes, and length to 34m have caused controversy. Key arguments among proponents are that HCVs will bring about benefits, such as: increasing energy efficiency and decreasing CO 2 emissions,

It has been hypothesized that to perform sensorimotor transformations efficiently, somatosensory information being fed back to a particular motor circuit is organized in accordance with the mechanical loading patterns of the skin that result from the motor activity generated by that circuit. Rearrangements of sensory information to different motor circuits could in this respect constitute a key co

Marine reptiles constitute a diverse group of secondarily aquatic tetrapods that have inhabited the world’s oceans for the greater part of the last 250 million years. While certain large-scale anatomical changes have been observed through progressive alterations of their skeletal morphology (e.g., the evolution of fin-like limbs), little is known about those changes that have occurred in the integ

The oxido-bridged diiron(III) complex [Fe2(μ-O)(μ-OAc)(DPEAMP)2](OCH3) (1), based on a new unsymmetrical ligand with an N4O donor set, viz. [2-((bis(pyridin-2-ylmethyl)amino)methyl)-6-((ethylamino)methyl)-4-methylphenol (HDPEAMP)], has been prepared and characterized by spectroscopic methods and X-ray crystallography. The crystal structure of the complex reveals that each Fe(III) ion is coordinate

Human cholangiocyte organoids are promising for regenerative medicine applications, such as repair of damaged bile ducts. However, organoids are typically cultured in mouse tumor-derived basement membrane extracts (BME), which is poorly defined, highly variable and limits the direct clinical applications of organoids in patients. Extracellular matrix (ECM)-derived hydrogels prepared from decellula

The human host defense peptide LL-37 has an essential role in the first line of defense against invading pathogens. This cathelicidin is mainly produced by immune cells and epithelial cells aligning the mucosal areas and is normally upregulated upon infection and inflammation. LL-37 displays direct antimicrobial activity against a variety of pathogens, but also modulates the immune responses by ac

Wine particle matter is mainly constituted by wine colloids and wine macromolecules. These wine colloidal and macromolecular compounds are barely studied, possibly due to the difficulty in facing the challenges that their study merits. These compounds are mainly formed by polyphenols, proteins and polysaccharides that come from the grape seeds, skins and pulp and even, to a lesser extent, from the

Recent attachment research attests that children’s relationships to preschool staff can contribute to their attachment development. The preschool introduction phase constitutes a natural arena for establishing these relationships, so organizing this introduction to enable relation-building between staff and children is essential. In Sweden, preschools stayed open during the covid-19-pandemic, howe

Background: Coronary flow reserve (CFR) is an index of coronary microcirculation. No previous reports exist on the association between testosterone levels and CFR. Therefore, the aim of the present study is to explore the association between testosterone and CFR in a group of men from the general population.Material and Methods: The study consisted of 66 men with no history of cardiovascular disea

This article examines the role of secrecy in relations between the NSU, the largest Danish national socialist youth organization, and parents. The NSU struggled to recruit and retain members from Danish families with and without national socialist convictions. By analysing how NSU media and internal correspondence framed parents’ reluctance to join, this article traces the changing functions of NS

We highlight important assumptions associated with the research program in sustainability science developed around “corporate biosphere stewardship” and the promise of “science-business initiatives.” In doing so, we interrogate a central concept in this research, “keystone actors.” We analyze the program based on associated research outputs and communications, focusing on three key challenges 1) i

The interpretation of x-ray emission spectroscopy (XES) spectra in terms of their sensitivity to the hydrogen bonding and the consequent microheterogeneity in liquid water has been debated over a decade. To shed a light on this problem, we report the theoretical reproduction of the debated 1b_{1} peaks observed in the XES spectra of liquid water using semiclassical Kramers-Heisenberg formula. The

The effect of the conformational state of the polymer coil on the properties of protein-polymer conjugates has been studied for the conjugates of antibody (monoclonal antibody from 6C5 clone against inactivated rabbit muscle glyceraldehyde-3-phosphate dehydrogenase; Ab) with poly(methacrylic acid) (PMAA) or poly-(acrylic acid) (PAA). The pH-dependencies of molecular properties and structural param

The Sda histo-blood group antigen (GalNAcβ1-4(NeuAcα2-3)Galβ-R) is implicated in various infections and constitutes a potential biomarker for colon cancer. Sd(a−) individuals (2–4% of Europeans) may produce anti-Sda, which can lead to incompatible blood transfusions, especially if donors with the high-expressing Sd(a++)/Cad phenotype are involved. We previously reported the association of B4GALNT2

Glioblastoma has remained the deadliest primary brain tumor while its current therapy offers only modest survival prolongation. Immunotherapy has failed to record notable benefits in routine glioblastoma treatment. Conventionally, immunotherapy relies on T cells as tumor-killing agents; however, T cells are outnumbered by macrophages in glioblastoma microenvironment. In this study, we explore the

Freshwater ecosystems are under multiple threats in modern times such as water extraction for human consumption, industries and agricultural activities, water contamination and habitat destruction for example. At the same time the biodiversity of these ecosystems are often poorly studied, especially in arid countries such as Iran. In this work, we study one of the ecologically important members of

The public management of urban space is an everyday practice that requires development. But how is creative work done in a public context? The idea of offering outdoor offices and outdoor conferences is being implemented in an open-air museum, owned by a middle-sized city in Sweden. This chapter focuses on their ambitions to be innovative, and the practices officials engage in, to innovate. The et

Nakhlite meteorites are igneous rocks from Mars that were aqueously altered ~630 million years ago. Hydrothermal systems on Earth are known to provide microhabitats; knowledge of the extent and duration of these systems is crucial to establish whether they could sustain life elsewhere in the Solar System. Here, we explore the three-dimensional distribution of hydrous phases within the Miller Range