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Health assessment measurements for patients with Rheumatoid arthritis (RA) have to be meaningful, valid and relevant. A commonly used questionnaire for patients with RA is the Stanford Health Assessment Questionnaire Disability Index (HAQ), which has been available in Swedish since 1988. The HAQ has been revised and improved several times and the latest version is the Multi Dimensional Health Asse
Coordination of apical constriction in epithelial sheets is a fundamental process during embryogenesis. Here, we show that DRhoGEF2 is a key regulator of apical pulsation and constriction of amnioserosal cells during Drosophila dorsal closure. Amnioserosal cells mutant for DRhoGEF2 exhibit a consistent decrease in amnioserosa pulsations whereas overexpression of DRhoGEF2 in this tissue leads to an
Using the Swedish military enlistment test, this paper estimates the return to schooling for individuals belonging to different parts of the ability distribution. It also attempts to predict whether an endogenous test score causes bias in the "ability-specific" returns to schooling that varies with the test score. A significant finding is that a higher score in the test is associated with a higher
Background: Activating KRAS and BRAF mutations predict unresponsiveness to EGFR-targeting therapies in colorectal cancer (CRC), but their prognostic value needs further validation. In this study, we investigated the impact of KRAS codons 12 and 13, and BRAF mutations on survival from CRC, overall and stratified by sex, in a large prospective cohort study. Methods: KRAS codons 12 and 13, and BRAF m
We assessed the relative merits of two approaches for including polarization effects in classical force fields for the sulfate anion. One of the approaches is the explicit shell model for atomic polarization and the other is an implicit dielectric continuum representation of the electronic polarization, wherein the polarizability density is spatially uniform. Both the solvation and ion association
This paper analyzes the effects of the interaction between technology adoption and incomplete enforcement on the extent of violations and the rate of abatement technology adoption. We focus on price-based and quantity-based emission regulations. First, we show that in contrast to uniform taxes, under tradable emissions permits (TEPs), the fall in permit price produced by technology adoption reduce
BACKGROUND: Interventions aimed at reducing the number of smokers are generally believed to be cost effective. However as the cost of the interventions should be paid up front whereas the gains in life years only appear in the future--the budgetary consequences might be a barrier to implementing such interventions. AIMS: The aim of the present paper was to assess the long-term cost effectiveness
We carried out a combined study of UV-VUV luminescence and resonant x-ray emission from BeO single crystals with incident photon energies in the vicinity of the Be 1s absorption edge. The x-ray emission spectra show that at the Be 1s photoabsorption edge the lattice relaxation processes in the excitation site take place already on the timescale of the radiative decay of the core excitation. Compar
As one of two well-exposed intraoceanic arcs, the Talkeetna arc of Alaska affords an opportunity to understand processes deep within arcs. This study reports new Lu-Hf and Sm-Nd garnet ages, Ar-40/Ar-39 hornblende, mica and whole-rock ages, and U-Th/He zircon and apatite ages from the Chugach Mountains, Talkeetna Mountains, and Alaska Peninsula, which, in conjunction with existing geochronology, c
Asymmetrical flow field-flow fractionation (AF4) is rapidly becoming a technique of choice for the separation and characterization of complex materials. It is capable of fractionating samples over a wide size (similar to 2 nm to 50 mu m in diameter) and molecular weight range (10(3)-10(10) g/mol). It offers gentle, low shear, low pressure separation conditions which are essential to preserve the s
Abstract This dissertation examines the function of metaphor and simile in Cicero’s dialogue De senectute. For this purpose, it employs Lakoff-Johnsonian metaphor theory and compares the metaphorical concepts that the scholars of that tradition have found in English with the metaphors found in Cicero’s text. Many languages are being investigated today by scholars who use this theory, and differen
CdTe semiconductor nanocrystals were synthesized with three different stabilizers: Mercaptoacetic Acid (MM), Mercaptopropionic Acid (MPA) and 2-Mercaptoethanol (ME) at pH approximate to 11.2 by wet chemical route using potassium tellurite and cadmium chloride as starting materials. The effect of capping agent on the preparation of these samples was evaluated using UV-Visible absorption and photolu
There is a general trend that parasitism risk declines as latitude increases. Host populations breeding at high latitudes should therefore invest less in costly immune defenses than populations breeding in temperate or tropical zones, although it is unknown if such an effect is mediated by environmental (photoperiodic) or genetic factors or both. Acquired immune function (humoral, cell-mediated) a
Cerebellar control of movements is dependent on mossy fiber input conveying information about sensory and premotor activity in the spinal cord. While much is known about spino-cerebellar systems, which provide the cerebellum with detailed sensory information, much less is known about systems conveying motor information. Individual motoneurones do not have projections to spino-cerebellar neurons. I
BACKGROUND/OBJECTIVES: Phytoestrogens are estradiol-like natural compounds found in plants that have been associated with protective effects against chronic diseases, including some cancers, cardiovascular diseases and osteoporosis. The purpose of this study was to estimate the dietary intake of phytoestrogens, identify their food sources and their association with lifestyle factors in the Europea
Service life planning and performance classification are key issues in the building sector. Well-functioning 'performance models' are absolutely essential to predict the service life and functionality of buildings, building assets, and building products overtime. Different types of performance models have been established for various building materials, but cannot necessarily transferred to wood-b
Electron beam optics (particle betatron motion) and trajectory (centroid secular motion) in the FERMI@Elettra free electron laser (FEL) are modeled and experimentally controlled by means of the ELEGANT particle tracking code. This powerful tool, well known to the accelerator community, is here for the first time fully integrated into the Tango-server based high level software of an FEL facility, t
The main objectives of the work presented in this thesis were to develop new experimental methods to improve the understanding of the release mechanism from a coated formulation and to develop new mechanistic models to describe the release process for pellets coated with a semi-permeable film. Another aim was to characterize the release mechanism from a formulation coated with films made of a blen
The psychometric properties of a Swedish version of Haidt, McCauley and Rozin's (1994) Disgust Scale were studied. Confirmatory factor analysis of the original model with eight factors (food, animals, body products, sex, body envelope violations, death, hygiene, and magic) provided satisfactory fit to the data (N= 280), significantly better than to the alternative one-factor and five-factor models
