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In this work, we experimentally study the effects of the nitrogen concentration in laser wakefield acceleration of electrons in a gas mixture of hydrogen and nitrogen. A 15 TW peak power laser pulse is focused to ionize the gas, excite a plasma wave and accelerate electrons up to 230 MeV. We find that at dopant concentrations above 2% the total divergence of the electrons is increased and the high
Sexual activity is important to older adults (65 +). Breathlessness affects about 25% of older adults but impact on sexual activity is unknown. We evaluated the relationships between breathlessness and sexual inactivity and self-reported health among older community-dwelling adults in the Australian Longitudinal Study of Ageing. Associations between self-reported breathlessness (hurrying on level
Face recognition occurs when a face is recognised despite changes between learning and test exposures. Yet there has been relatively little research on how variations in emotional expressions influence people’s ability to recognise these changes. We evaluated the ability to discriminate old and similar expressions of emotions (i.e. mnemonic discrimination) of the same face, as well as the discrimi
Objectives: One mechanism by which cartilage responds to mechanical load is by releasing heparin-bound growth factors from the pericellular matrix (PCM). By proteomic analysis of the PCM, we identified connective tissue growth factor (CTGF) and here investigate its function and mechanism of action. Methods: Recombinant CTGF (rCTGF) was used to stimulate human chondrocytes for microarray analysis.
This article analyses the effect of cultural diversity on employment growth, considering the recent global financial crisis (GFC) as a moderating factor. In doing so, we developed competing hypotheses based on Blau’s theory of heterogeneity versus an alternative perspective which combines the resource-based view (RBV) with social identity theory (SIT). We empirically test such theories using a uni
Background: The characteristics and prognosis of healthy obesity (HO) still remain unclear. We aimed to examine the characteristics of healthy severe obesity (HSO), defined by a novel approach, with a focus on self-reported physical activity (PA) and a genetic risk score for type 2 diabetes (GRS DM2). Methods: A cross-sectional analysis was carried out in a subsample of severly obese subjects (BMI
Introduction Anterior cruciate ligament (ACL) injury can result in joint instability, decreased functional performance, reduced physical activity and quality of life and an increased risk for post-traumatic osteoarthritis. Despite the development of new treatment techniques and extensive research, the complex and multifaceted nature of ACL injury and its consequences are yet to be fully understood
Background: Early cardiopulmonary resuscitation (CPR) and defibrillation with an Automated External Defibrillator (AED) increase survival from out-of-hospital cardiac arrest (OHCA). Although international guidelines recommend the use of AED registries to increase AED use, little is known about implementation. The aim of this paper is to describe the development of a national AED registry, to analy
Exponential integrators are becoming increasingly popular for stiff problems of high dimension due to their attractive property of solving the linear part of the system exactly and hence being A-stable. In practice, however, exponential integrators are implemented using approximation techniques to matrix-vector products involving functions of the matrix exponential (the so-called ϕ-functions) to m
Objectives: Successful gestational weight gain (GWG) restriction programs for obese (Body Mass Index (BMI) ≥ 30 kg/m2) pregnant women, have not, so far, shown convincing effects on infant's weight development. An intervention starting during the pregnancy might be too late and a pre-conceptional life style change may be preferable. Thus, the aim of this study was to follow children born to mothers
The multiconfiguration Dirac-Hartree-Fock theory is used to calculate the 3d9D3/22→2D5/2 transition energy for Co-like ions with Z=28-100. We investigate how electron correlation, frequency-independent and -dependent Breit interactions, as well as QED corrections vary along the sequence. The well-understood frequency-independent Breit contribution has the largest contribution for all ions. Among t
Objective: The aim of the analysis is to assess the impact of privately employed migrant care workers (MCWs) on the burden of Italian family members who care for a disabled older person. Methods: EUROFAMCARE is a one-year prospective survey carried out to provide evidence on the availability and use of support services by family carers of older people in Europe. In Italy, 990 family caregivers wer
Lakes and wetlands, common ecosystems of the high northern latitudes, exchange large amounts of the climate-forcing gases methane (CH4) and carbon dioxide (CO2) with the atmosphere. The magnitudes of these fluxes and the processes driving them are still uncertain, particularly for subarctic and Arctic lakes where direct measurements of CH4 and CO2 emissions are often of low temporal resolution and
While the so-called “end of public space” literature, focusing on encroachment of private interests and state surveillance, has contributed to critical thinking of access (or the lack thereof) to public space, and the loss of publicity of public space, the conceptual tools such literature offers to understand contestations in and over public space have remained underdeveloped or, at best, underexp
Vinculin is an essential and highly conserved cell adhesion protein, found at both focal adhesions and adherens junctions, where it couples integrins or cadherins to the actin cytoskeleton. Vinculin is involved in controlling cell shape, motility, and cell survival, and has more recently been shown to play a role in force transduction. The tail domain of vinculin (Vt) contains determinants necessa
The development of safe and effective vaccines for the prevention of elusive infectious diseases remains a public health priority. Immunization, characterized by adaptive immune responses to specific antigens, can be raised by an array of delivery vectors. However, current commercial vaccination strategies are predicated on the retooling of archaic technology. This review will discuss current and
