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Background: Primary indication for catheter ablation of atrial fibrillation (AF) is to reduce symptoms and improve health-related quality of life (HRQoL). There are data showing differences between the genders and between younger and older patients. To evaluate this, we studied a large Scandinavian cohort of patients referred for catheter ablation of AF. Methods: Consecutive patients filled out th
The number of patients with Alzheimer's disease (AD) is likely to triple in a few decades as the world's population ages. Given the high personal and societal burden of this disease, it is imperative to identify its risk factors. The etiology of AD is still not fully understood, but environmental factors have emerged as plausible important risk factors on the population-level. In this short review
Control charts have typically been constructed using estimators obtained under assumptions of data independence and a given distribution of data. Here, I deal with cases in which neither of these conditions are satisfied. In particular, I consider the case of data obtained from a first-order autoregressive (AR(1)) time series model that have been contaminated by outlying process observations. I fi
Directive 2003/54/EC of the European Commission set the ground for an integrated and liberalized electricity market in Europe. According to the law of one price the possibility for perfect arbitrage and the absence of trade restrictions lead to homogeneous goods being priced uniformly across countries. The aim of this study is to test whether the law of one price is applicable to the electricity m
Svår, elakartad och längre gången cancer är ett stort problem i förhindrande av spridda tumörceller i kroppen. I detta sjukdomsstadium är oftast en lindrande (palliativ) behandlingsform enda vägen att välja för att hjälpa patienten. För närvarande sker detta genom att patienten får genomlida extern strålbehandling eller cellgiftsbehandling. Radioaktivt märkta och ”målsökande” antikroppar injicerNew radionuclide therapies in humans should be preceded by experimental animal therapies, in order to evaluate the efficacy of the new therapy regime. These experimental studies have to be performed with a reliable and accurate quantification system, with properties that have been evaluated and where possible flaws have been corrected for. The aim of this work was to evaluate the SPECT pinhole col
Estrogen ( ER) and progesterone receptor (PgR) status was analysed in paraffin-embedded breast cancer material with immunohistochemical (IHC) technique and compared with corresponding analyses in cytosols ( CYT). ER showed the same status (positive/negative) with both methods in 88% of the samples (352/ 402). The concordance was also high for PgR status (81% [321/394]). Besides values near cut-off
Absorption and fluorescence spectra of 2-R-5-phenyl-1,3,4-oxadiazoles (R = H, methyl, tert-butyl, trifluoromethyl, amino, phenyl, benzyl) were studied experimentally and by time dependent density functional theory (TDDFT) methods. In acidic media a substantial red shift is observed due to the presence of conjugate acid forms. Two conjugate acid forms (3H and 4H) are possible for unsymmetrically su
Trots att jordbrukets näringsutsläpp till Östersjön har minskat krävs mycket mer för att uppnå de uppsatta miljömålen. Vi har utvärderat politiken som används för att minska utsläppen från de nio länder som samarbetar om restaureringen av Östersjön. Vi finner att den nuvarande politiken är otillräcklig eftersom:Många länder har inte genomfört de utlovade åtgärderna för att minska näringsutsläpp fr
PURPOSE Heart failure (HF) is a potentially life-threatening complication of treatment for childhood cancer. We evaluated the risk and risk factors for HF in a large European study of long-term survivors. Little is known of the effects of low doses of treatment, which is needed to improve current treatment protocols and surveillance guidelines.METHODSThis study includes the PanCareSurFup and ProCa
In this study, we aimed to explore the frequency of use and perceived usefulness of LLM generative AI chatbots (e.g., ChatGPT) for schoolwork, particularly in relation to adolescents’ executive functioning (EF), which includes critical cognitive processes like planning, inhibition, and cognitive flexibility essential for academic success. Two studies were conducted, encompassing both younger (Stud
While climate models broadly agree on the changes expected to occur over the Arctic with global warming on a pan-Arctic scale (i.e. polar amplification, sea ice loss, and increased precipitation), the magnitude and patterns of these changes at regional and local scales remain uncertain. This limits the usability of climate model projections for risk assessments and their impact on human activities
Considering the unstable condition of water resources in Iran and many other countries in arid and semi-arid regions, groundwater studies are very important. Therefore, the aim of this study is to model groundwater potential by qanat locations as indicators and ten advanced and soft computing models applied to the Beheshtabad Watershed, Iran. Qanat is a man-made underground construction which gath
The relationship between field measurements of vegetation in a semi arid region and NDVI from the 1 km NOAA AVHRR was investigated within this study. The Hoanib catchment in the northwestern Namibia was chosen as study area. The field measurements were carried out during the month of February 1999. Different NDVI values and combinations of NDVI were used and it was found that the integrated NDVI u
Objective: To describe the epidemiology of injuries and illnesses sustained during the Beijing 2022 Paralympic Winter Games, organised in a closed-loop environment to adhere with COVID-19 restrictions. Methods: Injuries and illnesses from all teams were recorded on a daily basis by team medical staff on a web-based form and by local organising committee medical (polyclinic) facilities and venue me
We determined the risk of late morbidity and mortality after autologous blood or marrow transplantation (BMT) for lymphoma performed before age 40. The cohort included autologous BMT recipients who had survived ≥2 years after transplantation (N = 583 [HL = 59.9%; NHL = 40.1%]) and a comparison cohort (N = 1070). Participants self-reported sociodemographics and chronic health conditions. A severity
Since 1958, cell culture media supplemented with fetal bovine serum is used, despite the well-known concerns about animal welfare, reproducibility, reliability, relevance, and safety. To obliterate these concerns and increase scientific accuracy, we recently published an open access, publicly available paper on a defined medium composition to make it possible for any lab to prepare this medium. Th
Purpose: Ultrahypofractionated (UHF) radiation therapy (RT) has become a treatment alternative for patients with localized prostate cancer. In more advanced cases, seminal vesicles (SVs) are routinely included in the target volume. The Scandinavian HYPO-RT-PC trial, which compared 42.7 Gy in 7 fractions (fr) to conventional fractionation (CF), did not include SVs in the clinical target volume. The
