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Use of image-guided radiation therapy (IGRT) helps to account for daily prostate position changes during radiation therapy for prostate cancer. However, guidelines for the use of IGRT are scarce. An ESTRO panel consisting of leading radiation oncologists and medical physicists was assembled to review the literature and formulate a consensus guideline of methods and procedure for IGRT in prostate c
The exact mechanism of action of IVIg in the amelioration of immune thrombocytopenic purpura (ITP) is still unclear. Studies have suggested that IVIg may function through the regulation of cytokines, including interleukin-1 receptor antagonist (IL-1Ra), an inhibitor of phagocytosis. Using a mouse model relevant to ITP, we confirm an increase in mouse serum levels of IL-1Ra after exposure to IVIg,
Background. In general practice, dysfunctions within the locomotor system are a recurring health issue. Most frequently, diagnoses and treatments relate to pain syndromes of the backbone, the shoulder girdle or the pelvic girdle. The authors believe that physiotherapy, along with other clinical disciplines, should be regarded as an important factor which influences the effectiveness of the therape
Two low-power mm-wave voltage controlled oscillators (VCOs) designed in a 28-nm fully-depleted silicon-on-insulator (FD-SOI) CMOS process are demonstrated, using a push-pull differential architecture. Measurement show that the first VCO has a 10.8% tuning rage centered at 30.3 GHz, and the second has a 8.9 % tuning range at 58.7 GHz. The 30 GHz VCO consumes 1.06 mW from a 1 V supply, and has a -11
Essentials Protein S and FV-Short are synergistic cofactors to Tissue Factor Pathway Inhibitor α (TFPIα). An assay for the TFPIα synergistic cofactor activity of protein S with FV-Short was developed. The assay was specific for the synergistic TFPIα-cofactor activity of free protein S. Protein S deficient individuals with known mutations were correctly distinguished from controls. Summary: Backgro
The social-democratic-inspired “Nordic model”, with its agenda for gender equality, has been an important example for the development of political interventions to transform society but at the same time, it has functioned as an emerging gender normalising and stabilising structure. In the last decade it has also become the focus of antigender movements and ethno-nationalistic parties both as emble
Searches for dijet resonances with sub-TeV masses using the ATLAS detector at the Large Hadron Collider can be statistically limited by the bandwidth available to inclusive single-jet triggers, whose data-collection rates at low transverse momentum are much lower than the rate from standard model multijet production. This Letter describes a new search for dijet resonances where this limitation is
The age relationship between sunburns and malignant melanoma was investigated in a population-based, matched, case-control study from the South Swedish Health Care Region (the highest risk area for melanoma in Sweden). Between 1988 and 1990, a total of 400 patients with a first diagnosis of malignant melanoma and 640 healthy controls aged 15-75 years answered a comprehensive questionnaire includin
The radiometric distortion of reflected radiation received by the NOAA AVHRR sensor is brought on by the effects of viewing and solar illumination geometry, as well as atmospheric effects. This may lead to a gross underestimation of bioproductivity or crop yield from models which use high temporal resolution NOAA AVHRR data as an input. Accordingly, a simple angular correction method is presented
Objective: To describe dietary habits and use of mineral supplements in relation to nutrient recommendations and anaemia. Design: a population-based cohort study. Subjects: 2665 men and 3878 women, born between 1926 and 1945, randomly invited and participating in the prospective 'Malmo Diet and Cancer study' during 1991-1992. Methods: The diet was assessed using a combined 7-day menu book for hot
Evaluation of Article 17(7) and (9) Directive 2019/790 on copyright in the Digital Single Market (DSM Directive) establishing an interface between the obligations of online content-sharing service providers in Article 17(1)-(4) DSM Directive, and the European system of limitations in Article 5 Directive 2001/29 (InfoSoc Directive). Part II, published on the Kluwer Copyright Blog.
The 2015 Paris Agreement aims to strengthen the global response to climate change, and to maintain an average global temperature well below 2°C, with aspirations toward 1.5°C, by means of balancing sources and sinks of greenhouse gas emissions. Following this, the importance of carbon dioxide removal in global emission pathways has been further emphasized, and Negative Emissions Technologies (NETs
GLPG1972/S201086 is a disintegrin and metalloproteinase with thrombospondin motif-5 (ADAMTS-5) inhibitor in development as an osteoarthritis disease-modifying therapy. We report the safety, tolerability, pharmacokinetics, and pharmacodynamics (turnover of plasma/serum ARGS-aggrecan neoepitope fragments [ARGS]) of GLPG1972 in 3 randomized, double-blind, placebo-controlled phase 1 trials. Study A, a
Few studies have investigated the relationships between organic food consumption, dietary patterns, monetary diet cost, health, and the environment. To address these issues, a consortium of French epidemiologists, nutritionists, economists, and toxicologists launched the BioNutriNet project in 2013. In 2014, an FFQ documented the usual organic and nonorganic (conventional) food consumption of appr
