Filetype
Background and objectives: Neuroinflammation is implicated in the development and maintenance of persistent pain states, but there is limited data linking cerebrospinal fluid (CSF) inflammatory mediators with neurophysiological pain processes in humans. Study I aimed to investigate whether there are coherent changes in CSF inflammation associated with central sensitization (CS), and to evaluate po
Objective: To report outcomes of urgent juxtarenal/pararenal aneurysms (J/P-AAAs) managed by off-the-shelf multibranched thoracoabdominal endografts (Cook, T-branch). Methods: In this observational, multicenter, retrospective study, patients with J/P-AAAs treated by urgent endovascular repair by T-branch in 23 European aortic centers, from 2013 to 2023, were analyzed. Contained J/P-AAAs rupture, p
IMPORTANCE: Prostate-specific antigen (PSA) screening has potential to reduce prostate cancer mortality but frequently detects prostate cancer that is not clinically important.OBJECTIVE: To describe rates of low-grade (grade group 1) and high-grade (grade groups 2-5) prostate cancer identified among men invited to participate in a prostate cancer screening protocol consisting of a PSA test, a 4-ka
Background: Current systemic therapies for metastatic pancreatic ductal adenocarcinoma are associated with poor outcomes with a 5-year overall survival rate under 5%. We aimed to assess the safety and antitumour activity of mitazalimab, a human CD40 agonistic IgG1 antibody, with modified FOLFIRINOX (mFOLFIRINOX; fluorouracil, leucovorin, oxaliplatin, and irinotecan), in chemotherapy-naive patients
Importance: Recent studies have questioned the presumed low-risk status of patients with asymptomatic nonsevere aortic stenosis (AS). Whether annual N-terminal pro-brain natriuretic peptide (NT-proBNP) measurements are useful for risk assessment is unknown. Objective: To assess the association of annual NT-proBNP measurements with clinical outcomes in patients with nonsevere AS. Design, Setting, a
Atrial cardiomyopathy, characterized by abnormalities in atrial structure and function, is associated with increased risk of adverse cardiovascular and neurocognitive outcomes, independent of atrial fibrillation. There exists a critical unmet need for a clinical tool that is cost-effective, easy to use, and that can diagnose atrial cardiomyopathy. P wave parameters (PWPs) reflect underlying atrial
This article describes two inter-related research projects concerned with the teaching and learning of English in contemporary contexts, where English is changing its status from being the first language of specific groups of speakers to becoming a global lingua franca. Focussing respectively on learners of English as a second language (L2 users) in the Netherlands and Sweden, and on native speake
BACKGROUND: In Sweden, as in many other countries, official monitoring of healthcare quality is mostly focused on geographical disparities in relation to a desirable benchmark. However, current evaluations could be improved by considering: (1) The intersection of other relevant axes of inequity like age, sex, income and migration status; and (2) The existence of individual heterogeneity around ave
Background: The apolipoprotein E (APOE) ε4 allele is associated with higher cholesterol levels, and an increased risk of developing Alzheimer’s disease (AD) and amyloid-related imaging abnormalities after initiation of amyloid-modifying therapies. A worse cognitive response to cholinesterase inhibitor (ChEI) treatment and longitudinal outcome in APOE ε4-carriers has been observed. Based on these c
Popular Abstract in Swedish Avhandlingen handlar om hur fett (lipider) i kosten bryts ner och transporteras i blodet för att slutligen antingen användas som energi, byggstenar i cellväggarna eller lagras i fettväven. I den här avhandlingen kan man också läsa om hur man kan modifiera fetter med hjälp av speciella proteiner: enzymer för att förbättra näringsinnehållet och dess fysikaliska egenskaperAn important indicator of the metabolic capacity of humans is the ability to regulate plasma triacylglycerol levels and to clear triacylglycerol-rich lipoproteins (TRLs) from the circulation after a meal. This is crucial since most of the day is spent in the postprandial state. High concentrations and long circulation times of TRL remnants may be detrimental since these are considered to be highly
Importance: Long-term follow-up after transcatheter aortic valve replacement (TAVR) is of interest given that longitudinal data on mortality and durability of transcatheter heart valves are limited. The REPRISE III (Repositionable Percutaneous Replacement of Stenotic Aortic Valve Through Implantation of Lotus Valve System-Randomized Clinical Evaluation) randomized clinical trial compared the mecha
IMPORTANCE: The clinical utility of stress cardiovascular magnetic resonance imaging (CMR) in stable chest pain is still debated, and the low-risk period for adverse cardiovascular (CV) events after a negative test result is unknown.OBJECTIVE: To provide contemporary quantitative data synthesis of the diagnostic accuracy and prognostic value of stress CMR in stable chest pain.DATA SOURCES: PubMed
The aim of the project MASTER (MAnaging Speeds of Traffic on European Roads) was to produce information that can be cited in the preparation of national and EU decisions concerning speed management and speed control equipment standards. For this purpose, the project looked for answers to three key questions: 1)What are acceptable ranges of speeds? 2)What are the key factors influencing drivers’ ch
The European Association of Urology (EAU) Renal Cell Carcinoma (RCC) Guideline Panel performed a protocol-driven systematic review (SR) on thermal ablation (TA) compared with partial nephrectomy (PN) for T1N0M0 renal masses, in order to provide evidence to support its recommendations. The Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines were followed, and only
Scholarship on media and politics presumes a ‘mediatization’ of politics over time, which overlooks the evolution of a mediatized public sphere that shaped people’s understandings of what actually constituted politics. This article investigates the public sphere to demonstrate how it created expectations for politicians and journalists within the process of the mediatization of politics. To unders
Lending conditions LUND UNIVERSITY LIBRARIES Lending conditions in brief • Loans can be made to persons with a Swedish personal identity number or coordination number, who are over 18 years of age. • Guest students or –researchers must show a letter of acceptance or certificate of affiliation, to get a library card at Lund University Libraries. • You must always be prepared to show your library ca
https://www.lub.lu.se/en/sites/lub.lu.se.en/files/lanevillkor_2017_eng_webb-2.pdf - 2026-07-18
Nyhetsbrev 2018 till dig som deltar i ett världsunikt projekt Det är sjätte gången som Ingrid kommer till GÅS- projektets mottagning i Malmö, och hon har nu hunnit fylla 102 år. Hon har varit med sedan forsk- ningsprojektet började och tycker att det har varit in- tressant att få vara med och hjälpa till med forskning, särskilt eftersom hon själv har blivit äldre. Vissa delar av undersökningen tyc
https://www.geriatrik.lu.se/sites/geriatrik.lu.se/files/nyhetsbrev2018_fin.pdf - 2026-07-18
GÅS Nyhetsbrev för året 2018 Nyhetsbrev 2018 till dig som deltar i ett världsunikt projekt 102-åringen som varit med sedan det började Det är sjätte gången som Ingrid kommer till GÅS- projektets mottagning i Malmö, och hon har nu hunnit fylla 102 år. Hon har varit med sedan forsk- ningsprojektet började och tycker att det har varit in- tressant att få vara med och hjälpa till med forskning, särski
https://www.geriatrik.lu.se/sites/geriatrik.lu.se/files/nyhetsbrev2018_fin_tg.pdf - 2026-07-18
Interdisciplinary – The IIIEE has a genuine interdisciplinary approach synthesizing insights not only from economic theory and practice but also from natural sciences, engineering, political science, organizational, legal and behavioural studies. The IIIEE academic staff has backgrounds in diverse disciplines. Collaboration – The IIIEE education and research are performed in close collaboration wi
https://www.iiiee.lu.se/sites/iiiee.lu.se/files/arsrapport_web_0.pdf - 2026-07-18
