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There is a great need to identify new and better prognostic and predictive biomarkers to stratify prostate cancer patients for optimal treatment. The aims of this study were to characterize the expression profile of pre-B cell leukemia homeobox (PBX) transcription factors in prostate cancer with an emphasis on investigating whether PBX3 harbours any prognostic value. The expression profile of PBX3

A Swedish pedigree with an autosomal dominant inheritance of idiopathic scoliosis was initially studied by genetic linkage analysis, prioritising genomic regions for further analysis. This revealed a locus on chromosome 1 with a putative risk haplotype shared by all affected individuals. Two affected individuals were subsequently exome-sequenced, identifying a rare, non-synonymous variant in the C

PARP14/BAL2 is a large multidomain enzyme involved in signaling pathways with relevance to cancer, inflammation, and infection. Inhibition of its mono-ADP-ribosylating PARP homology domain and its three ADP-ribosyl binding macro domains has been regarded as a potential means of therapeutic intervention. Macrodomains-2 and -3 are known to stably bind to ADP-ribosylated target proteins, but the func

This book is a key component of a PhD thesis derived from the artistic researchproject; How Little is Enough? and contains the essay Testimony of a Pilgrim andmanuscripts from the four performances that are central to the research project. Theentire PhD thesis is mediated through an on-line exposition on Research Catalogueusing mixed formats. The exposition encompasses the complete researchoutput

The retrotransposon Long Interspersed Element 1 (LINE-1 or L1) is a continuing source of germline and somatic mutagenesis in mammals. Deregulated L1 activity is a hallmark of cancer, and L1 mutagenesis has been described in numerous human malignancies. We previously employed retrotransposon capture sequencing (RC-seq) to analyze hepatocellular carcinoma (HCC) samples from patients infected with he

Arbetsrehabilitering Efterfrågan på evidensbaserade insatser har ökat markant i Sverige och Individual Placement and Support (IPS) är en av de högst prioriterade psykosociala insatserna i Socialstyrelsens nationella riktlinjer. Utbildningen har gått regelbundet sedan 2012 och fokuserar nu även på Supported Education. Särskild tonvikt i utbildningen kommer att läggas vid implementeringen av IPS i b

https://www.medicin.lu.se/sites/medicin.lu.se/files/uppdragsutbildning_ips_ht_2020.pdf - 2026-07-09

Amid growing geopolitical tensions and the shift toward a multipolar world, research security has emerged as a critical concern for academic institutions and national governments. While efforts to protect science from foreign interference and intellectual property theft are increasing, many current measures lack empirical grounding, clear objectives, or proven effectiveness. This paper discusses t

“The Future is distributed: a vision of sustainable economies” is a collection of case studies on distributed economies, a concept describing sustainable alternatives to the existing business models. The authors of this publication are international Masters students of the Environmental Sciences, Policy and Management Programme at the International Institute for Industrial Environmental Economics

https://www.ch.lu.se/evenemang/avstampet-2026 - 2026-07-07

The Department of Economics is one of the largest departments within Lund University School of Economics and Management. The number of students registered at the department during an academic year amounts to approximately 2,000. Just over 100 people are more or less firmly connected to the department's activities as teachers, researchers, doctoral students and administrative staff. Department lead

https://www.lusem.lu.se/organisation/department-economics/about-department-economics - 2026-07-08

Fotboll och juridik är två system som under en längre tid setts som distinkt separata från varandra. Likväl, i takt med att den europeiska fotbollsindustrin fortsätter att växa gör också behovet av förutsägbar och hållbar lagstiftning det. Under de senaste trettio åren har Europeiska unionens domstol (EU-domstolen) kontinuerligt definierat idrottens särart som en undantagsprincip för sportindustriFootball and law are two systems that for a long time has been seen as distinctively separate from each other. However, as the European footballing industry continues to grow, so does the need for predictable and sustainable legislation. Throughout the last thirty years the Court of Justice of the European Union (CJEU) has been continuously defining the specificity of sport as a principle of exemp