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The paper presents a feasibility study for a Climate Prediction Data Assimilation System following the methodological approach of the Carbon Cycle Data Assimilation System (CCDAS). The usefulness of accurate gradient information for estimating process parameters of the spectral atmospheric circulation model PUMA on climate time-scales is investigated. Pseudo observations of the long-term mean surf
We present the DEAL language for heap assertions that are efficiently evaluated during garbage collection time. DEAL is a rich, declarative, logic-based language whose programs are guaranteed to be executable with good whole-heap locality, i.e., within a single traversal over every live object on the heap and a finite neighborhood around each object. As a result, evaluating DEAL programs incurs ne
We present SMITE, a toolbox for the measurement of eye movements using eye trackers manufactured by SMI GmbH. The toolbox provides a wrapper around the iViewX SDK provided by SMI, allowing simple integration of SMI eye trackers into Psychophysics Toolbox and PsychoPy programs. The toolbox provides a graphical interface for participant setup and calibration that is implemented natively in Psychophy
The paper suggests conditions for presence of quadratic Lyapunov functions for nonlinear observer based feedback systems with an 'input nonlinearity' in the feedback path. Provided that the system using state feedback satisfies the Circle Criterion (i.e., when all states can be measured), we show that the extended system with only output feedback control from a (full state) Luenberger-type observe
We present post-compression of a TW class laser in a planar hollow waveguide. The viability of the compressed pulses for applications in strong-field physics is demonstrated by generating high-order harmonics in a gas jet.
For a firm in an open source software (OSS) ecosystem, the requirements engineering (RE) process is rather multifaceted. Apart from its typical RE process, there is a competing process, external to the firm and inherent to the firm’s ecosystem. When trying to impose an agenda in competition with other firms, and aiming to align internal product planning with the ecosystem’s RE process, firms need
A new carbon isotope record with conodont biostratigraphy is presented for the entire Early Triassic from the Musandam Peninsula, United Arab Emirates (UAE). This is a near-continuous and exclusively shallow marine carbonate succession that allows analysis of a high-resolution primary carbon cycling signature in the absence of significant depth-dependent or lithologic controls. The Musandam carbon
The possibility of analysis by the detection of elastically scattered particles for carbon, nitrogen, oxygen and also hydrogen determination in the fine mode of aerosols has been investigated. The main objectives in this study have been to find suitable projectiles (protons or alpha particles) and projectile energy, in order to obtain separated peaks for the elements of interest and to achieve hig
Despite the initial promise of immunotherapy for CNS disease, multiple recent clinical trials have failed. This may be due in part to characteristically low penetration of antibodies to cerebrospinal fluid (CSF) and brain parenchyma, resulting in poor target engagement. We here utilized transcranial macroscopic imaging to noninvasively evaluate in vivo delivery pathways of CSF fluorescent tracers.
The fourth version of the Ariadne program for generating QCD cascades in the colour dipole approximation is presented. The underlying physics issues are discussed and a manual for using the program is given together with a few sample programs.The major changes from previous versions are the introduction of photon radiation from quarks and inclusion of interfaces to the LEPTO and PYTHIA programs.
Portugal has a unitary system in which the central government transfers funds to lower government levels for their public functions. In 2007, Portugal introduced Ecological Fiscal Transfers (EFT), where municipalities receive transfers for hosting protected areas (PA). We study whether introducing EFT in Portugal incentivized municipalities to designate PA and has led to a decentralization of cons
Along with the review of the technological frame that will be available at the Extreme Light Infrastructure Attosecond Light Pulse Source (ELI-ALPS) we present considerations applicable to large-scale attosecond sources driven by high-power laser pulses.
We propose that impaired complement function enhances a pathogenetic vicious circle in SLE. In this process, induction and clearance of apoptotic cells is central. Apoptosis could be triggered by various etiological factors, such as infection, UV light, and drug reactions. Clearance of apoptotic material is reduced when complement function is impaired. Apoptosis leads to increased exposure of nucl
Previous studies on organic sediment contaminants focused mainly on a limited number of highly hydrophobic micropollutants accessible to gas chromatography using nonpolar, aprotic extraction solvents. The development of liquid chromatography–high-resolution mass spectrometry (LC–HRMS) permits the spectrum of analysis to be expanded to a wider range of more polar and ionic compounds present in sedi
There is a need to develop new techniques for quantitative measurement of receptors expression on particular vasculature cells types. Here, we describe and demonstrate a novel method to measure quantitatively and simultaneously the expression of endothelin B receptor (ETB) on vascular smooth muscle cells (VSMC). We isolated cells from male rat tissues such as: brain pial, brain intraparenchymal an
An increasing demand for energy-efficient buildings has led to an increasing focus on predicted energy performance once a building is in use. Many studies have identified a performance gap between predicted energy use and actual measured energy use once buildings are in the user phase. However, none of the identified studies normalise measured energy use for both internal and external deviating bo
Refugee rights are reserved for the few lucky enough to evade the sophisticated deterrence regime, while the vast majority of the world’s refugees are referred to a life in semi-permanent limbo.
Background: Early diagnosis of traumatic acute full-thickness rotator cuff tears (FTRCT) is important to offer early surgical repair. Late repairs following fatty infiltration of the rotator cuff muscles have less favorable results. We think that physical therapists are valuable diagnosticians in a screening process. The objective of this study was to evaluate the usefulness of physical therapists
The treatment of Parkinson's disease (PD) has for over 50 years relied on dopaminergic therapies that are highly effective especially in the early years of the condition, but ultimately are limited by the development of side effects that relate to the nonphysiological stimulation of dopamine receptors including in nonstriatal areas. Targeted regenerative therapies designed to restore specifically
