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Reliable prediction tools are yet to be developed for estimating the accurate acoustic performance of lightweight structures, which are vital especially in the design process. This paper presents a sound insulation prediction model based on artificial Neural Networks (NN) to estimate acoustic performance for airborne and impact sound insulation of floor structures. At an initial stage, the predict
Binge eating disorder (BED) is associated with several psychological and medical problems, such as obesity. Approximately 30% of individuals seeking weight loss treatments present binge eating symptomatology. Moreover, current treatments for BED lack efficacy at follow-up assessments. Developing mindfulness and self-compassion seem to be beneficial in treating BED, although there is still room for
Importance: Local steroid injection is commonly used in treating patients with idiopathic carpal tunnel syndrome, but evidence regarding long-term efficacy is lacking. Objective: To assess the long-term treatment effects of local steroid injection for carpal tunnel syndrome. Design, Setting, and Participants: This exploratory 5-year extended follow-up of a double-blind, placebo-controlled randomiz
Intrinsic molecular subtypes may explain marked variation between bladder cancer patients in prognosis and response to therapy. Complex testing algorithms and little attention to more prevalent, early-stage (non-muscle invasive) bladder cancers (NMIBCs) have hindered implementation of subtyping in clinical practice. Here, using a three-antibody immunohistochemistry (IHC) algorithm, we identify the
Conservation efforts have mainly been focused on depleted species or populations, but many formerly reduced marine mammal populations have recovered to historical abundances. This calls for new management strategies and new models for ecological risk assessment that incorporate local density dependence and multiple environmental stressors. The harbor seal metapopulation in Swedish and Danish water
We have built a new small furnace to perform high temperature studies up to 1200°C in vacuum or in oxygen atmosphere. This furnace was originally used as a catalytic reactor optimized for the in situ X-ray Absorption Spectroscopy experiments on beamline ID24. It has now been redesigned for use on the ESRF beamline ID01 for in situ Grazing Incidence Small Angle X-ray Scattering experiments. For the
Radiocarbon (14C), as a consequence of its production in the atmosphere and subsequent dispersal through the carbon cycle, is a key tracer for studying the Earth system. Knowledge of past 14C levels improves our understanding of climate processes, the Sun, the geodynamo, and the carbon cycle. Recently updated radiocarbon calibration curves (IntCal20, SHCal20, and Marine20) provide unprecedented ac
OBJECTIVE: To identify and characterize genetic loci associated with the risk of developing anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV).METHODS: Genetic association analyses were performed after Illumina sequencing of 1,853 genes and subsequent replication with genotyping of selected SNPs in a total cohort of 1110 Scandinavian cases with granulomatosis with polyangiit
Microfluidics has emerged as an essential approach in the development of novel technological platforms to detect and isolate rare circulating tumor cells (CTCs) in the blood of cancer patients. Micro-scaled fluidic systems offer means to precisely control fluid flow. This enables cell separation when combined with techniques for manipulating cells across fluid streams. Various microfluidic methods
In order to understand species’ sensitivity to habitat change, we must correctly determine if a species is associated with a habitat or not, and if it is associated, its degree of specialization for that habitat. However, definitions of species’ habitat association and specialization are often static, categorical classifications that coarsely define species as either habitat specialists or general
Background: Although housing accessibility is associated with important health outcomes in other populations, few studies have addressed this in a Parkinson’s disease population. Aim: To determine the most severe environmental barriers in terms of housing accessibility problems and how these evolved over 3 years among people with Parkinson’s disease. Material and Methods: 138 participants were inc
Objectives: In this study, we aimed to assess the stratification ability of the Fracture and Mortality Risk Evaluation (FAME) index for reoperation, new fragility fracture, and mortality during one-year follow-up. Patients and methods: Between November 2018 and July 2019, a total of 94 consecutive hip fragility fracture patients from two centers (20 males, 74 females; mean age: 79.3±8.9 years; ran
Biological drugs such as tumor necrosis factor (TNFα) blockers are very successful and effective in therapy of chronic inflammatory disease. These blockers bind TNFα and inhibit its pro-inflammatory function. But unfortunately, biological drugs are immunogenic and prolonged treatment triggers the formation of anti-drug antibodies and neutralizing antibodies (NAbs). This reaction is associated with
There are competing standards regarding the definition of the crime of “enforced disappearance” under international law. When criminalizing enforced disappearance at the national level as part of their obligations under international law, States which adopt a more narrow definition of enforced disappearance provided in the Rome Statute require victims of enforced disappearance to prove the existen
The Nuremberg Charter introduced the crime of aggression into international law. The American Chief Prosecutor Justice Robert Jackson gave a famous promise that offenders who commit acts of aggression shall be prosecuted and international criminal law would be applied against them. However, only at the first Review Conference of the ICC Statute in Kampala 2010, agreement on a universally accepted
In a progressively globalized world the catapults of economic globalization, is in large, due to increased flows of foreign direct investments (FDI) across the world. FDI flows are considered essential vehicles for economic growth and development. The complex entities that embody a multinational company (MNC ) are often simplified to encompass either an exploitation approach of LDCs by MNCs or the
The aim of this thesis has been to investigate the legal conditions and process for triggering Credit Default Swaps, which are derivative instruments to shift credit risk exposure between parties in an underlying financial instrument. The condition is called credit event and a case study has been done on the Greek credit event in 2012. The thesis shows that there is a clear and robust framework o
