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Remaining competitive as a company in a rapidly changing global environment is becoming challenging from day to day. In recent years, the establishment of so-called shared service centers gained popularity and growing number of companies centralizes supporting service in separate business units to bundle those services and perform them efficiently for the rest of the company. The mystery, however,
am509781CEE_SV_BAT E U R 2 16 20 MÄNSKLIGA RESURSER www.europa.eu.int/eracareers/europeancharter Europeiska stadgan för forskare Riktlinjer för rekrytering av forskare am509781CEE_SV_BAT 8/12/05 16:25 Page 1 Interested in European research? RTD info is our quarterly magazine keeping you in touch with main developments (results, programmes, events, etc). It is available in English, French and Germa
https://www.lu.se/sites/www.lu.se/files/eur_21620_sv-en.pdf - 2026-07-07
Commercialization has been recognized as one of the most difficult phases of the innovation process. Failure rates are high, even for products with the potential to address real needs and deliver real customer value. This master's thesis explores commercialization in an even more challenging business context than the typical case. First, the innovating company is an early startup with limited
The purpose of this report is to map how HTA, Health Technology Assessment, is being used for MDD products for inpatient care in Sweden. Swedish Medtech, a professional association for medical technology companies, has a need to carry out a survey about the use of HTA in Sweden for their future work. They have a project which goal is to inform policy makers about the value of innovative medical pr
In the social sciences, many quantitative research findings as well as presentations of demographics are related to participants’ gender. Most often, gender is represented by a dichotomous variable with the possible responses of woman/man or female/male, although gender is not a binary variable. It is, however, rarely defined what is meant by gender. In this article, we deconstruct the concept ‘ge
How genome-wide association studies-identified single-nucleotide polymorphisms (SNPs) affect remote genes remains unknown. Expression quantitative trait locus (eQTL) association meta-analysis on 496 prostate tumor and 602 normal prostate samples with 117 SNPs revealed novel cis-eQTLs and trans-eQTLs. Mediation testing and colocalization analysis demonstrate that MSMB is a cis-acting mediator for S
Tropomyosin-related kinase A (TrkA) receptor mediates the effects exerted by nerve growth factor on several subpopulations of neuronal cells. Ligand binding to TrkA induces receptor autophosphorylation on several tyrosine residues and the activation of signaling cascades. In this study, we describe a new site relevant for TrkA regulation, the tyrosine 701 (Y701), which is important for receptor tr
Women with breast cancer and micrometastases only constitute a treatment dilemma. If only a micrometastasis is found in a sentinel lymph node, an axillary lymph node dissection may be considered to be overtreatment and perhaps could be avoided. However, studies have shown decreased survival in patients with micrometastases only. This paper focuses on the pathological work-up behind the classificat
Objectives: To investigate whether pancreatic steatosis is associated with the presence of pancreatic cysts among individuals with diabetes. Material and Methods: 158 individuals [mean age 66 ± 10 years, 81 (51%) female] with diabetes [135 (85%) had type 2 diabetes] participated in the study involving Magnetic Resonance Imaging (MRI), blood tests and anthropometric measurements. Pancreatic steatos
The Methodology used to gather empirical materials for this thesis has been different types of interviews. The interviews have been mainly unstructured personal interviews directly with our respondents, due to limiting factors some of the interviews have been carried out via phone or email. The theoretical framework consists of literature from well-recognised authors and is divided into four diffe
The aggregating proteoglycans (aggrecan, versican, neurocan, and brevican) are important components of many extracellular matrices. Their N-terminal globular domain binds to hyaluronan, but the function of their C-terminal region containing a C-type lectin domain is less clear. We now report that a 90-kDa protein copurifies with recombinant lectin domains from aggrecan and versican, but not from t
Summary The bacterial endospore is a dormant and heat-resistant form of life. StoA (SpoIVH) in Bacillus subtilis is a membrane-bound thioredoxin-like protein involved in endospore cortex synthesis. It is proposed to reduce disulfide bonds in hitherto unknown proteins in the inter-membrane compartment of developing forespores. Starting with a bioinformatic analysis combined with mutant studies we i
