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Epilepsy is one of the most common neurological disorders and affects over 65 million people worldwide. Despite the continuing advances in anti-epileptic treatments, one third of the epilepsy patients live with drug resistant seizures. Besides, the mortality rate among epileptic patients is 2 - 3 times higher than in the matching group of the general population. Wearable devices offer a promising

Insufficient nursing care is a major threat to a patient’s safety. Despite the development of evidence-based guidelines (EBGs) guiding the delivery of high-quality and effective nursing care, research presents an inadequate implementation of EBGs in clinical practice. Patients who appear to receive insufficient nursing care are older patients (≥65 years) with community-acquired pneumonia (CAP), a

The manuscript is devoted to optimal control for a class of linear positive systems with linear objective function and linear constraints. The solution to the corresponding Bellman equation is a linear value function, which can be found by linear programming.

The nature of the few known solar-mass stars simultaneously containing debris disks and planets remains an open question. A number of works have shown that this property appears to be independent of planetary masses as well as of stellar age, but possible correlations with stellar kinematics and metallicity have not been investigated. In this paper, we show that the majority of known stars contain

The aim of this article is to design a moment transformation for Student-t distributed random variables, which is able to account for the error in the numerically computed mean. We employ Student-t process quadrature, an instance of Bayesian quadrature, which allows us to treat the integral itself as a random variable whose variance provides information about the incurred integration error. Advant

Current techniques to determine functional or effective connectivity from magnetoencephalography (MEG) and electroencephalography (EEG) signals typically involve two sequential steps: 1) estimation of the source current distribution from the sensor data, for example, by minimum-norm estimation or beamforming, and 2) fitting a multivariate autoregressive (MVAR) model to estimate the AR coefficients

This paper proposes an interaction and safety-aware motion-planning method for an autonomous vehicle in uncertain multi-vehicle traffic environments. The method integrates the ability of the interaction-aware interacting multiple model Kalman filter (IAIMM-KF) to predict interactive multi-modal maneuvers of surrounding vehicles, and the advantage of model predictive control (MPC) in planning an op

Objective: Emerging research suggests that rheumatoid arthritis (RA) is associated with intestinal dysbiosis. This prospective pilot study evaluates changes in intestinal microbial composition in patients with RA initiating treatment with either methotrexate (MTX) or a tumor necrosis factor inhibitor (TNFi). Methods: Consecutive patients, fulfilling the 2010 American College of Rheumatology/EULAR

Flow-ELISA measurements of the monoclonal antibody concentration in cultivation broth containing murine hybriboma cells were carried out using a small expanded-bed column (0.5×2.5 cm) charged with protein A. A new specialised pellicular agarose/stainless steel matrix designed for high flow rates with fast mass transport properties was used. Special care was taken to get an efficient flow dist

Microbial, algal, plant and animal cells have been immobilized, with preserved viability, by entrapment in various matrices according to a new bead polymerization technique. The cell polymer/monomer mixture is kept suspended in a hydrophobic phase such as soy, paraffin, or silicon oil, tri-n-butylphosphate, or dibutyphtalate, which is compatible with the cells. The various monomers or polymers tes

This chapter articulates a strategic canvas for degrowth, based on a dialogue with the work of Erik Olin Wright. It argues that degrowth strategies for social- ecological transformation need to combine several strategic approaches, reflecting the plurality of degrowth as a movement. To support the myriad of bottom-up alternatives that are already out there, degrowth actors should put a special emp

In this article, we propose a novel solution to detect multiple targets using a distributed multiple-input multiple-output (MIMO) radar under the so-called 'defocused transmit-defocused receive' operating mode. The proposed method employs a grid-based data matching algorithm, aiming to associate the target responses to potential target locations, solving the resulting data puzzle that evaluates th

Leptons with essentially the same properties apart from their mass are grouped into three families (or flavours). The number of leptons of each flavour is conserved in interactions, but this is not imposed by fundamental principles. Since the formulation of the standard model of particle physics, the observation of flavour oscillations among neutrinos has shown that lepton flavour is not conserved

We study steady axisymmetric water waves with general vorticity and swirl, subject to the influence of surface tension. This can be formulated as an elliptic free boundary problem in terms of Stokes' stream function. A change of variables allows us to overcome the generic coordinate-induced singularities and to cast the problem in the form “identity plus compact,” which is amenable to Rabinowitz's

Polymeric anion-exchange membranes (AEMs) with alkali-stable quaternary ammonium (QA) cations are essential components for the development of alkaline membrane fuel cells and water electrolyzers. Ionic loss by β-elimination reactions typically accelerates at low water contents, i.e., high alkali concentrations, which makes QA cations attached to polymer backbones via benzylic sites interesting alt