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Summary. Over the last few decades, clinical follow-up of patients with haemophilia has become more complex as a result of the introduction of new treatment strategies, the presence of comorbidities related to haemophilia or ageing, as well as the emergence of new tools to evaluate the medical and social consequences of haemophilia. This publication describes the parameters and information that sh
A devastating complication associated with negative-pressure wound therapy (NPWT) after cardiac surgical intervention is heart rupture resulting in serious bleeding. The benefit of a rigid barrier between the underlying organs and the sharp sternal edges has been demonstrated in pigs. In the present article, we present our first 6 patients with deep sternal wound infection treated with NPWT in com
Multiple myeloma (MM) is a disease of immunoglobulin producing plasma cells which reside mainly in the bone marrow. Family members of MM patients are at a risk of MM but whether other malignancies are in excess in family members is not established and is the aim of this study. MM patients (24,137) were identified from the Swedish Cancer Registry from years 1958-2012. Relative risks (RRs) were calc
The empirical-bias bandwidth selector (EBBS) is a method for data-driven selection of bandwidths for local polynomial regression. It is a bandwidth selection method for estimation of the mean-function and its partial derivatives of any order as well as for estimation of the variance-function. Moreover EBBS allows for univariate as well as multivariate predictor variables. In this paper we introd
Topic: This paper reviewed the current literature regarding time use among people with psychiatric disabilities. Purpose: The purpose was to investigate what characterizes time use, occupational balance and occupational patterns among people with psychiatric disabilities, how time use relates to health in this group, and how time use can be used in research designs and addressed in assessments and
A design model development for electrical machines with laminated windings is presented. The focus is to provide manufacturable solutions for commercial vehicle traction applications. The machine is designed with axially distributed single-layer wave-winding segments with a core that builds a modular three-phase machine. The phase segment, whose central part is a wave-winding made as a laminated w
Bayesian optimization (BO) has become an established framework and popular tool for hyperparameter optimization (HPO) of machine learning (ML) algorithms. While known for its sample-efficiency, vanilla BO can not utilize readily available prior beliefs the practitioner has on the potential location of the optimum. Thus, BO disregards a valuable source of information, reducing its appeal to ML prac
There exist several datasets for developing self-driving car methodologies. Manually collected datasets impose inherent limitations on the variability of test cases and it is particularly difficult to acquire challenging scenarios, e.g. ones involving collisions with pedestrians. A way to alleviate this is to consider automatic generation of safety-critical scenarios for autonomous vehicle (AV) te
TensorView for MATLAB is a GUI-based visualization tool for depicting second-rank Cartesian tensors as surfaces on three-dimensional molecular models. Both ellipsoid and ovaloid tensor display formats are supported, and the software allows for easy conversion of Euler angles from common rotation schemes (active, passive, ZXZ, and ZYZ conventions) with visual feedback. In addition, the software dis
Many algorithms in computer graphics make use of acceleration structures such as Bounding Volume Hierarchies (BVHs) to speed up performance critical tasks, such as collision detection or ray-tracing. However, while the typical algorithms for constructing BVHs are relatively simple, actually implementing them for performance critical systems is still challenging. Further, to construct them as quick
Small modular reactors (SMRs) have become part of the solution for futurefossil-free energy systems. Compared to traditional nuclear power plants (NPPs), risks are different and additional actors are involved. The aim of this paper is to analyse key actors’ understanding of emergency preparedness for SMRs in Sweden. Emergency preparedness is an active, continuous and integrated process involving a
Parallel-elastic joints can improve the efficiency and strength of robots by assisting the actuators with additional torques. For these benefits to be realized, a spring needs to be carefully designed. However, designing robots is an iterative and tedious process, often relying on intuition and heuristics. We introduce a design optimization framework that allows us to co-optimize a parallel elasti
IntroductionGlobal water scarcity necessitates innovative approaches to water treatment. Membrane technology has emerged as a key solution, demonstrating its effectiveness across a range of applications, from seawater desalination using reverse osmosis to wastewater treatment with membrane bioreactors. This presentation will introduce three novel water treatment concepts based on membrane technolo
Objective: To evaluate (1) the frequency of aquaporin-4 antibody (AQP4-ab)-seropositive cases among patients treated with natalizumab (NAT) and previously diagnosed with MS (MSNAT) in a nationwide cohort, (2) the clinical course of NAT-treated AQP4-ab-seropositive neuromyelitis optica spectrum disorder (NMOSD) patients (NMONAT), (3) AQP4-ab titers in NMONAT and AQP4-ab-seropositive NMOSD treated w
Future Internet-of-Things (IoT) systems need to combine heterogeneous IoT components and support weak connectivity. This paper introduces ComPOS, a domain-specific language for composing IoT services into systems. ComPOS is a small language but supports powerful message mediation, using stateful reactions with nested and parallel message sequences and anonymous futures. To deal with weak connectiv
This work is to extend studies of business model (BM) experimentation for sustainable value creation using three cases; here incumbent firms apply resources/networks in pursuit of sustainability-oriented BMs via corporate entrepreneurship. A focus query is: How do organisations apply experimentation to learn, signal and convince key resource holders to engage with shifts (from incumbent BMs) to mo
We are interested in rationalizing the phenomenon of like-charge attraction between charged bodies, such as a pair of colloids, in the strong coupling regime. The two colloids are modelled as uniformly charged parallel plates, neutralized by mobile counterions. In an earlier work [Palaia et al., J. Phys. Chem. B 126, 3143 (2022)1520-610610.1021/acs.jpcb.2c00028], we developed an effective-field th
In this paper we study the numerical quadrature of a stochastic integral, where the temporal regularity of the integrand is measured in the fractional Sobolev-Slobodeckij norm in Wσ,p(0,T), σ ∈(0,2), p∈[2,∞). We introduce two quadrature rules: The first is best suited for the parameter range σ ∈(0,1) and consists of a Riemann-Maruyama approximation on a randomly shifted grid. The second quadrature
