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To investigate the effects of a vitamin D3 analogue (BXL628) in a model of chronic cystitis, as calcitriol analogues might be an interesting new therapeutic option for interstitial cystitis, for although the cause of the disease remains unclear, the increase in mast cells in the mucosa and detrusor muscle are significant. We devised a mouse model of allergen-induced allergic cystitis that is assoc
Those who carry the mutated gene will develop the fatal Huntington’s disease at some stage in life. The brain disease, which can be inherited across generations, begins slowly and makes it increasingly difficult for sufferes to regulate their feelings, thoughts, and eventually movements. There is still no treatment. However, Huntington researcher and psychiatrist Åsa Petersén is working hard at it
A fateful decision as a 15-year-old high school student, and good advice from a distinguished professor of zoology, were the catalysts that not only decided my entire career but also led me to the Journal of Comparative Physiology A, and to the myriad biological wonders that were held within its covers. In my celebration of JCPA, I look back on the formative years of my career in Australia, and th
A 4π radiation dosemeter for use in medical radiology was designed. It is based on a solid state silicon detector, a sensor wafer, a flex card, a 3D plastic holder and a spherical stainless steel filter with a distribution of holes around the detector. The detector is attached to the wafer using only low Z material. To achieve an energy and directional response which is as uniform as possible for
Titel: Unlock my potential! – en uppsats om hur projektledare kan frigöra och ta tillvara individers kreativitet för att främja serviceorganisationers innovationsförmåga Universitet: Lunds Universitet, Campus Helsingborg, Institutionen för Service Management Kurs: SMTX07 Service Management: Examensarbete – Magisterkurs, 15hp, VT 2010 Seminariedatum: 1 juni 2010 Författare: Kristin Lagerström och C
This thesis analyzes how and why old toys are restored by and for adults, despite contemporary Western society's understanding of toys as signifiers of childhood exclusively. With this in mind, the intent is to answer whether childhood attachments to toys can also be observed in adults by analyzing how the restoration process of toys reaffirms emotional and social significance for all involved
Background: The accumulation of amyloid-β1−42 (Aβ1−42) peptides and phosphorylated-Tau181 (p-Tau181) tangles from the preclinical stages of Alzheimer’s disease (AD) has led to a biological definition of the disease. However, among Aβ1−42-positive individuals, cognitive decline onset varies, and some never develop symptoms. Genetic influences on molecular pathways and their interactions with protei
