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Hypertensive disorders of pregnancy, including preeclampsia, are major contributors to maternal morbidity. The goal of this study was to evaluate the potential of metabolomics to predict preeclampsia and gestational hypertension from urine and serum samples in early pregnancy, and elucidate the metabolic changes related to the diseases. Metabolic profiles were obtained by nuclear magnetic resonanc
Context. The Gaia-ESO Survey (GES) is a large public spectroscopic survey at the European Southern Observatory Very Large Telescope. Aims. A key aim is to provide precise radial velocities (RVs) and projected equatorial velocities (v sin i) for representative samples of Galactic stars, which will complement information obtained by the Gaia astrometry satellite. Methods. We present an analysis to e
A pilot plant was set up to treat leachate from an industrial landfill containing shredder residues of end-of-life vehicles and white goods. The treatment plant consisted of aeration and sedimentation steps for pre-treatment, and a filter. The plant was designed to simultaneously remove various types of pollutants. The efficiencies of pre-treatment and of the main treatment step were investigated
This thesis has as a purpose the investigation of sustainable requirements compliance with regards to competition in public procurement contracts. This paper looks into Directive 2014/24 and notably its primary law influence in order to understand the legal foundations underlying sustainability and competition. It showcases, firstly, that Article 18(1) wording and legal interpretation provides a l
This paper empirically investigates the relationship between industrial ownership and environmental degradation in the People’s Republic of China, with specific focus on two environmental indicators: volume of SO2 emissions and volume of industrial wastewater deemed unsafe for discharge. Sulfur dioxide and untreated wastewater emissions are considered some of the most problematic environmental and
Complex recombinant biomaterials that merge the self-assembling properties of different (poly)peptides provide a powerful tool for the achievement of specific structures, such as hydrogel networks, by tuning the thermodynamics and kinetics of the system through a tailored molecular design. In this work, elastin-like (EL) and silk-like (SL) polypeptides are combined to obtain a silk-elastin-like re
This study examines the production of morphosyntax in Swedish-speaking children diagnosed with Developmental Language Disorder (DLD). Data from a Sentence Repetition Task was used to investigate if there is an implicational order according to Processability Theory (PT) in grammatical structures produced by school-age children with DLD. PT is a cognitive theory of language development that assumes
Cerebrospinal fluid (CSF) α-synuclein (α-syn) seed amplification assays (SAAs) can detect Lewy body pathology (LBP) with high accuracy but are invasive and costly. To address these challenges, this study evaluated a two-step workflow combining prescreening via smell-function testing with confirmatory CSF α-syn SAA testing only in individuals with reduced smell, for predicting postmortem LBP status
Prehistorical musical instruments have been explored in archaeology more systematically since the 1970s when music archaeology was established as a field of study. The new awareness initially led to studies centred on retrieving musical instruments that had been missed and were now lost in archives. New discoveries, too, are very object-oriented. This master’s thesis ties together individual finds
Moderate exercise is deemed beneficial for cognition due to increase in dopamine concentrations in the basal ganglia. Auditory white noise is beneficial for cognition, mainly for those with lower attentional ability, i.e. for those having lower tonic dopamine concentrations. For individuals with higher attention ability white noise can have a negative effect. In this thesis it was examined whether
Longitudinal Metabolome-Wide Signals Prior to the Appearance of a First Islet Autoantibody in Children Participating in the TEDDY Study Longitudinal Metabolome-Wide Signals Prior to the Appearance of a First Islet Autoantibody in Children Participating in the TEDDY Study Qian Li,1 Hemang Parikh,1 Martha D. Butterworth,1 Åke Lernmark,2 William Hagopian,3 Marian Rewers,4 Jin-Xiong She,5 Jorma Toppar
https://www.teddy.lu.se/sites/teddy.lu.se/files/117_mp224_li_et_al._metabolomics_diabetes.pdf - 2026-07-23
Tuvalu, a low-lying Small Island Developing State (SIDS), is projected to face severe challenges due to climate change. Most notably, permanent inundation or the permanent loss of habitable land due to sea-level rise. This thesis investigates how Tuvalu has framed climate change as an existential security threat in its international discourse from 2021 to 2023. Applying an adapted version of secur
This work explores the catalytic activity of decavanadate (V10)-based catalysts in the selective oxidation of ethylbenzene (EB), a model compound of lignin-derived molecules, under mild conditions. The goal is to assess the catalytic efficiency, product selectivity, and the influence of counter-ions on activity through systematic testing of parameters such as temperature and catalyst loading. Addi
All vårdpersonal bör ges grundläggande kunskaper om smärtsinnet, reaktioner på smärta samt behandling av olika typer av smärta. Sjuksköterskor ska dessutom ha god kännedom om tekniker för smärtskattning, om psykologiska faktorers betydelse och om traditionella smärtstillande läkemedels kliniska användning (SoS-rapport 1994:4). Syftet med denna studie var att undersöka förekomst, innehåll och mål f
Bristande handhygien inom vården är ett globalt problem och det finns ett samband mellan låg följsamhet av rutiner för handhygien och förekomsten av vårdrelaterade infektioner. Syftet med denna studie var att undersöka sjuksköterskors syn på orsaker till bristande handhygien samt vilka möjligheter som finns för förbättringar. För att undersöka detta användes ett frågeformulär med öppna frågor som
It is described in the preparatory work of the Social Services Act that a reasonable standard of living should be based on the prevailing conditions under which the individual lives. Because there is no specified description of the phrase, this entails interpretability of the phrase and therefore uncertainty about what it infers. The purpose of this study is to analyse the representation of the ph
The aim was to perform a bibliometric study, and compare the quantity of publications on schizophrenia with the total medical literature in Medline during 57 years, 1950-2006. The annual additions of literature to Medline are continually increasing and form the Medline growth curve. Comparisons of the number of publications on schizophrenia, or any other disease, to this curve, may be used to esti
BACKGROUND: In Crohn's disease high tissue expression and serum levels of chemokines and their receptors are known to correlate with disease activity. Because statins can reduce chemokine expression in patients with coronary diseases, we wanted to test whether this can be achieved in patients with Crohn's disease. METHODOLOGY/PRINCIPAL FINDINGS: We investigated plasma levels of chemokines (CCL2, C
Hepatitis D virus (HDV) is dependent on the presence of hepatitis B virus (HBV) for transmission and replication because of its inability to produce its own coat. It remains unclear whether HDV infection increases the risk of hepatocellular carcinoma. Using the Swedish Hospital Discharge Register and Outpatient Registry, we identified 9160 patients with chronic HBV infection between 1997 and 2008,
