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Objectives. Accidents in health care, resulting in injury or death to the patient, are a matter of considerable concern. The aim of this study is to examine whether system weaknesses can contribute to these accidents, and if so, how. Design. Eight consecutive accidents reported to the Health Authority in Sweden were analysed using MTO (Man-Technique-Organization) analysis. Setting. Emergency care
Batch processes are becoming more and more important in the chemical process industry, where they are used in the manufacture of specialty materials, which often are highly profitable. Some examples where batch processes are important are the manufacturing of pharmaceuticals, polymers, and semiconductors. The focus of this thesis is exception handling and fault detection in batch control. In the
The Gq-coupled 5-hydroxytryptamine 2B (5-HT2B) receptor is known to regulate the proliferation of islet beta cells during pregnancy. However, the role of serotonin in the control of insulin release is still controversial. The aim of the present study was to explore the role of the 5-HT2B receptor in the regulation of insulin secretion in mouse and human islets, as well as in clonal INS-1(832/13) c
If we admit that, with the exception of language, human perception is predominantly visual, it is reasonable to think that all phenomena conveyed by the visual senses have something in common, but then visual semiotics/visual culture will comprehend much more than painting, sculpture, and architecture. The double coding hypotheses of cognitive psychology, as well as Lessing’s classical opposition
Popular Abstract in Swedish Syftet med studierna som presenteras i denna avhandling har varit att undersöka om fordonsetanol kan framställas på ett lönsamt och energieffektivt sätt från restprodukter från jord- och skogsbruk enligt svenska förhållanden. Mycket av den forskning som rör andra-generationens etanolproduktion går ut på att förfina och förbättra de separata delstegen i framställningsproSweden has claimed that it wants to have a fossil-free vehicle fleet in 2030 as a milestone of its ambitious goal for 2050 to be a country with a sustainable and resource-efficient energy supply without any net GHG emissions. Production of bioethanol from plant materials is one potential method of meeting this goal. A large amount of research has been devoted toward the development of sustainable
The purpose was to study age related changes in circulatory system via Ballistocardiography (BCG) by utilizing Electromechanical Film (EMFi) sensors by gradually changing the ambient temperature from a thermoneutral area to cold direction. ECG and BCG were recorded from a young person (23 years) and from an older person (78 years), both males. During the tests, brachium blood pressure (BP) and pul
The Global Land-Atmosphere Climate Experiment-Coupled Model Intercomparison Project phase 5 (GLACE-CMIP5) is a multimodel experiment investigating the impact of soil moisture-climate feedbacks in CMIP5 projections. We present here first GLACE-CMIP5 results based on five Earth System Models, focusing on impacts of projected changes in regional soil moisture dryness (mostly increases) on late 21st c
Background: Cognitive rigidity and working memory impairment are established features of internalizing syndromes. Growing evidence suggests that deficits in affective control –cognitive control in the context of emotion – may underpin elevated emotion-related impulsivity in various psychiatric disorders. Objective: This study examines two components of affective control (affective flexibility and
This report evaluates and compares the methods in fire inspection at Malmø Fire Brigade and Copenhagen Fire Brigade. The report also examines fire safety laws and regulations and the educational differences of the fire inspectors in Malmø and Copenhagen. The investigation is a project for Malmø Fire Brigade and Copenhagen Fire Brigade in co-operation with the Department of Fire Safety Engineering
This report describes and addresses patterns of discrimination in Sweden’s care sector, primarily related to gender and migrant status. It examines national legislation, collective agreements, case law, and equality bodies’ activities concerning equal treatment, pay transparency, parental leave, and occupational safety. It highlights the highly feminised nature of the care workforce, persistent ge
Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer lacking effective drugs and therefore new treatment targets are needed. In this study, we define the role of homeobox protein B6 (HOXB6) and HOXB8 in controlling pancreatic cancer tumorigenesis and immune response. Transcriptomic analysis comparing human embryonic and PDAC tissue identified a large overlap of expression profiles suggesting
Artificial intelligence (AI) is increasingly being discussed at the international level, with a particular focus on its potential to help achieve the Sustainable Development Goals (SDGs). The Global Digital Compact, adopted at the Summit of the Future, calls for the establishment of international institutions to govern AI technologies. The impact of AI on sustainable development is a multifaceted
The Andean lakes of northern Chile and southern Bolivia are characterized by their high salinity due to arid climate and high evaporation. These lakes are poorly studied due to access difficulties. The aim of this study is to characterize two shallow saline lakes in northern Chile (Salar de Atacama, 23°S, Chile) and South Lipez of Bolivia (Khalina lake, 22.61°S) using satellite images (Landsat 8).
Background: Depression and suicidal behavior have been linked to increased blood-brain barrier (BBB) permeability. Platelet-derived growth factor receptor beta (PDGFR-β) is widely expressed in pericytes and promotes BBB integrity. Here, we investigated cerebrospinal fluid (CSF) levels of PDGFR-β in suicide attempters and healthy controls and correlated PDGFR-β to depression symptom severity. Metho
While many studies have examined carbon dynamics of boreal ecosystems following wildfire, research on forest-atmosphere carbon fluxes during widespread smoke events from adjacent active wildfires is limited. We examined eddy covariance carbon exchange adjacent to the May 2011 Utikuma Complex wildfire in central Alberta, Canada. Over a one-week period while the wildfire was burning <10 km from the
Simulating temporal changes in breast tissue has been challenging, despite advancement in virtual clinical trials. This study aims to enable virtual trials over time, motivated by interest in the effect of tissue involution on tumor visibility. We present a framework for creating 3D voxel-based breast phantoms and lesions using in-house Perlin Noise-based algorithm. The framework consists of three
Climate change may affect the yield of mass-flowering crops by altering the interplay between pest pressure and service delivery by pollinators, but realistic predictions need to account for the frequent use of insecticides in conventional farming. We tested the interactive effects of insecticide use and warmer winter conditions on oilseed rape (Brassica napus) production, pest pressure, and the a
Hexavalent chromium (Cr(VI)) can induce oxidative stress, genomic instability, and epigenetic modifications. In occupational settings, Cr(VI)-exposed workers may also be exposed to other toxicants, such as elements besides Cr, and per- and polyfluoroalkyl substances (PFAS). However, research on the extent of these co-exposures and their combined effects remains limited. The objective of this study
