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Vitamin C may impact the efficiency of radiation therapy (RT) in breast cancer. The effects of RT alone or in combination with vitamin C in SKBR3, MDA-MB-231, and MCF7 cells were compared using clonogenic assay, proliferation assay (MTT), cell cycle analysis, and Western blot. Vitamin C use was assessed in 1803 breast cancer patients 2002–2017 in relation to clinicopathological features and recurr
Organized human papillomavirus (HPV) vaccination was introduced in Sweden in 2012. On-demand vaccination was in effect from 2006 to 2011. We followed the HPV prevalences in Southern Sweden from 2008 to 2013.
Neurotensin regulates both satiety and breast cancer growth in the experimental setting, but little is known about its role in the development of breast cancer or cardiometabolic disease in humans.
[Context and motivation] When developing software, coordination between different organizational units is essential in order to develop a good quality product, on time and within budget. Particularly, the synchronization between requirements and verification processes is crucial in order to assure that the developed software product satisfies customer requirements. [Question/problem] Our research
Motivation: The requirements engineering (RE) research community is aware of the importance of performing feasibility studies before starting requirements elicitation. Unfortunately, projects still frequently fail to achieve commercial success, responsibility is often unknown, and requirements engineers may be deemed responsible for mistakes made by others. Problem: There is neither empirical evid
Emission trading schemes (ETS) have emerged as a popular climate policy measure and are increasingly advocated as policy instruments to support the transition to a green economy. Using complementary analytical methods, this research investigated the institutional developments and complexities of the New Zealand Emissions Trading Scheme (NZ ETS). It focuses on (1) institutional experience and admin
Knowledge of human fetal blood development and how it differs from adult blood is highly relevant to our understanding of congenital blood and immune disorders and childhood leukemia, of which the latter can originate in utero. Blood formation occurs in waves that overlap in time and space, adding to heterogeneity, which necessitates single-cell approaches. Here, a combined single-cell immunopheno
α-Synuclein is an intrinsically disordered presynaptic protein associated with Parkinson's disease. The physiological role of α-Synuclein is not fully understood, but the protein is known to interact with lipid membranes. We here study how membrane charge affects the adsorption of α-Synuclein to (i) supported lipid bilayers and (ii) small unilamellar vesicles with varying amounts of anionic lipids
Purpose: to propose two enhancements for the European Union’s Circular Material Use rate (CMU): inclusion of Preparation for Reuse (PfR) flows and enhanced reproducibility across lower levels of analysis. Methods: PfR flows are added to the material flow Sankey Diagram. The Local Circularity Rate (LCR) is based in the CMU and is broke down in three waste-related ratios: recovered-to-treated (RCV-t
Heart failure (HF) is a leading cause of death and disability globally. Heritable factors and the extent and pattern of myocardial fibrosis are important determinants of outcomes in patients with HF. In a genome-wide association study of mortality in HF, we recently identified a genetic polymorphism on chromosome 5q22 associated with HF mortality. Here, we sought to study the mechanisms by which t
Despite low or undetectable plasma viral load, people living with HIV-2 (PLWH2) typically progress toward AIDS. The driving forces behind HIV-2 disease progression and the role of viremia are still not known, but low-level replication in tissues is believed to play a role. To investigate the impact of viremic and aviremic HIV-2 infection on target and bystander cell pathology, we used data-indepen
Energy is essential for the sustenance of life. The energy and economy of any nation are interlinked—energy demand is generally proportional to the economic growth of the nation. In the present era, renewable energy (RE) is the primary area of interest to save fossil fuels, achieve sustainability, and reducing carbon emissions, as well as other gases in the atmosphere that create climatic problems
If we admit that, with the exception of language, human perception is predominantly visual, it is reasonable to think that all phenomena conveyed by the visual senses have something in common, but then visual semiotics/visual culture will comprehend much more than painting, sculpture, and architecture. The double coding hypotheses of cognitive psychology, as well as Lessing’s classical opposition
Popular Abstract in Swedish Syftet med studierna som presenteras i denna avhandling har varit att undersöka om fordonsetanol kan framställas på ett lönsamt och energieffektivt sätt från restprodukter från jord- och skogsbruk enligt svenska förhållanden. Mycket av den forskning som rör andra-generationens etanolproduktion går ut på att förfina och förbättra de separata delstegen i framställningsproSweden has claimed that it wants to have a fossil-free vehicle fleet in 2030 as a milestone of its ambitious goal for 2050 to be a country with a sustainable and resource-efficient energy supply without any net GHG emissions. Production of bioethanol from plant materials is one potential method of meeting this goal. A large amount of research has been devoted toward the development of sustainable
The purpose was to study age related changes in circulatory system via Ballistocardiography (BCG) by utilizing Electromechanical Film (EMFi) sensors by gradually changing the ambient temperature from a thermoneutral area to cold direction. ECG and BCG were recorded from a young person (23 years) and from an older person (78 years), both males. During the tests, brachium blood pressure (BP) and pul
Syftet med rapporten är identifiera och analysera uppfattningar om brott i Bosnien under och efter kriget samt beskriva i vilken mån inblandande parter i en konflikt kan förlåta varandra eller försonas. Den empiriska delen av uppsatsen bygger på observationer i Ljubija, tidningsartiklar från området samt fjorton intervjuer. I analysdelen diskuteras det empiriska materialet med utgångspunkt från DuWhat is percieved as a crime in war time varies depending on the war at issue, the eventual peace, the victors and the victims. This study focuses on the resolution of rules that occured in Ljubija, a town in the north-western part of Bosnia-Herzegovina, during the the war 1992-1995, and how it created new conflicts and group formations that live on after the war. After the war a competition for t
Syftet med denna studie är att analysera hur ungdomar som varit placerade på särskilda ungdomshem upplever, definierar och tolkar ett behandlingsprojekt, som involverade olika myndigheter, benämnt Motverka Våld och Gäng. Dessutom uppmärksammas hur de tolkade de i projektet anställda samordnarna. Den personliga aspekten i relationen mellan ungdomar och samordnare framställs som viktig och det verkThe purpose of this study is to analyse the way young people who were institutionalised in so called special youth-homes experienced, defined and iterpreted on the one hand the project “Motverka Våld och Gäng” (meaning: “Counteract Violence and Gangs”), and on the other hand the Coordinators employed in this project. There is a big variation in the perception of the coordinators. One common deno
