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BACKGROUND: Suicide is a major global health problem, especially among youth. Suicide is known to be associated with a variety of social, economic, political and religious factors, vary across geographical and cultural regions. The current study aimed to investigate the effects of socioeconomic factors on suicide mortality rate across different regions in Iran.METHODS: The data on distribution of
A comparative experimental investigation has been performed, comparing the emissions from a synthetic jet fuel and from Jet AI. In the investigation, the unburned hydrocarbons were analyzed chemically and the regulated emissions of NOX, CO and HC were measured. All combustion tests were performed under elevated pressures in a gas turbine combustor rig. A Swedish company, Oroboros AB, has developed
Deterministic lateral displacement (DLD) is a powerful bimodal separation scheme [1] based on fluid flow through regular obstacle arrays that in its basic embodiment sends suspended particles in two different directions as a function of size. We show that without the need to seal devices and without the need for fluidic connections or pumps, particle separation can be achieved by the passive flow
This chapter provides an overview of the main concepts in mechanobiology and touches upon the experimental models that are most frequently used to study mechanobiology on a cell and tissue level. It focuses on the use of computational techniques and algorithms to simulate mechanobiological processes, and their prospective potential in clinical applications. It covers how computational algorithms h
Treatment with anti-CD20 antibodies is only moderately efficient in chronic lymphocytic leukemia (CLL), a feature which has been explained by the inherently low CD20 expression in CLL. It has been shown that CD20 is epigenetically regulated and that histone deacetylase inhibitors (HDACis) can increase CD20 expression in vitro in CLL. To assess whether HDACis can upregulate CD20 also in vivo in CLL
Objective To evaluate the implementation of automated chest compression cardiopulmonary resuscitation (ACC-CPR) after out-of-hospital cardiac arrest (OHCA) in Sweden during the years 2011 through 2015. The association between ACC-CPR and 30-day survival was studied as a secondary objective. Methods The Swedish cardiopulmonary resuscitation registry is a prospectively recorded nationwide registry o
This paper demonstrates a new acoustofluidic approach to enrich extremely dilute cell suspensions 1000 times and higher, at flow rates of ≥0.5 mL/min and higher, addressing some of the needs in rare cell processing and water quality monitoring.
Self-adaptation provides a principled way to deal with change during operation. As more systems with strict goals require self-adaptation, the need for guarantees in self-adaptive systems is becoming a high-priority concern. Designing adaptive software using principles from control theory has been identified as one of the approaches to provide guarantees. However, current solutions can only handle
DNA carries the genetic code of life, with different conformations associated with different biological functions. Predicting the conformation of DNA from its primary sequence, although desirable, is a challenging problem owing to the polymorphic nature of DNA. We have deployed a host of machine learning algorithms, including the popular state-of-the-art LightGBM (a gradient boosting model), for b
Commentary and analysis of the proposal of the Swedish Ministry of Justice (Ds 2021:30) concerning implementation of Article 17 Directive 2019/790 on copyright and related rights in the Digital Single Market (DSM Directive). Part 2 of 2.
The members of the genus Caldicellulosiruptor have the potential for future integration into a biorefinery system due to their capacity to generate hydrogen close to the theoretical limit of 4 mol H2/mol hexose, use a wide range of sugars and can grow on numerous lignocellulose hydrolysates. However, members of this genus are unable to survive in high sugar concentrations, limiting their ability t
This chapter concerns disabled people’s experiences of barriers to accessing sexuality. It draws on an analysis of materials produced in ten projects by civil society organisations, including self-advocacy organisations, sexual rights organisations and organisations working on behalf of disabled people. These materials comprise books, handbooks, videos, websites and other online materials, and are
The aim of this study was to describe changes in the use of accident and emergency departments in the Copenhagen Hospital Co-operation after restricted admittance to the accident and emergency department at a large Danish university hospital, Rigshospitalet (admittance only for patients transported by ambulance or presenting with a referral from a doctor).MATERIAL AND METHODS: A retrospective stud
Formalized triage has been implemented in all Danish emergency departments. The validation behind formalized triage has focused on investigating predictive validity, i.e. correspondence between triage category and different outcome measures. Reliability is primarily investigated in terms of inter-rater reliability on written patient cases, and several studies have methodological limitations questi
BACKGROUND: As under-5 mortality rates declined all over the world, the relative distribution of under-5 deaths during different periods of life changed. To provide information for policymakers to plan for multi-layer health strategies targeting child health, it is essential to quantify the distribution of under-5 deaths by age groups.METHODS: Using 245 Demographic and Health Surveys from 64 low-
While research on the design of heterogeneous concurrent systems has a long and rich history, a unified design methodology and tool support has not emerged so far, and thus the creation of such systems remains a difficult, time-consuming and error-prone process. The absence of principled support for system evaluation and optimization at high abstraction levels makes the quality of the resulting im
BACKGROUND: Androgen insensitivity is caused by mutations in the androgen receptor gene, and is a common etiological factor to ambiguous genitalia in the newborn. This article discusses the role of androgens in sex differentiation, the structure and function of the androgen receptor, the genetic background to androgen insensitivity as well as clinical aspects. MATERIAL AND METHODS: The article is
