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In 2022 and 2023, the Large Hadron Collider produced approximately two billion hadronic interactions each second from bunches of protons that collide at a rate of 40 MHz. The ATLAS trigger system is used to reduce this rate to a few kHz for recording. Selections based on hadronic jets, their energy, and event topology reduce the rate to Ô(10) kHz while maintaining high efficiencies for important s
Simulation methods in breast imaging offer advantages over clinical trials in terms of improved reproducibility, reduced need for patient exposure to radiation, increased flexibility, and more clearly defined ground truth. Simulation also allows for improved representation of anatomical variations and variations in acquisition parameters and breast positioning related to multimodality imaging. The
The COVID-19 pandemic has jolted the health system globally and a paucity of specific drugs and/or vaccine hesitancy led clinicians to indiscriminately use antibiotics. Furthermore, during the early waves of the COVID-19 pandemic, several studies showcased the anti-SARS-CoV-2 efficacy of few antibiotics which further catapulted the idea of using them after emergency approval by the Food and Drug A
Forests are invaluable terrestrial ecosystems with considerable economic, ecological, and environmental benefits. Bark beetles have been recognized as one of the major causes of forest disturbance, and climate change can exacerbate their impact, leading to more tree mortality. Early detection of bark beetle attacks is vital to reduce forest loss and devastating consequences. This study examines th
High aspect ratio nanostructuring requires high precision pattern transfer with highly directional etching. In this work, we demonstrate the fabrication of structures with ultra-high aspect ratios (up to 10 000 : 1) in the nanoscale regime (down to 10 nm) by platinum assisted chemical etching of silicon in the gas phase. The etching gas is created by a vapour of water diluted hydrofluoric acid and
Background: The immunogenicity, safety, and efficacy of recombinant factor VIII (rFVIII) have gained increasing interest after the introduction of extended half-life products with various modifications of the rFVIII molecule, such as covalent attachment of polyethylene glycol (PEG). Anti-PEG antibodies may be associated with a temporary reduction of FVIII recovery, but according to previous studie
Transport of terrestrial carbon through riverine systems to coastal water has a negative impact on oxygen concentration in coastal areas. However, information on seasonal variation and the impact of catchment composition on the bioavailability of allochthonous carbon is lacking. In this project we address this knowledge gap by investigating the reactivity of dissolved organic carbon (DOC) at river
BACKGROUND Numerous laboratory tests are used in the diagnosis and management of patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these assays varies substantially. An expert committee compiled evidence-based recommendations for laboratory analysis in patients with diabetes. The overall quality of the evidence and the strength of the recommendations wer
Adjuvants have traditionally been appreciated for their immunoenhancing effects, whereas their impact on immunological memory has largely been neglected. In this paper, we have compared three mechanistically distinct adjuvants: aluminum salts (Alum), Ribi (monophosphoryl lipid A), and the cholera toxin A1 fusion protein CTA1-DD. Their influence on long-term memory development was dramatically diff
Over the past 30 to 40 years comprehensive fishery policies and certification schemes have attempted to halt the rapid decline and exploitation of commercial fish stocks. However, with seafood as one of the most globalized food commodities and the world’s population increasing exponentially, most commercial stocks are thought to be on the brink of collapse. Some estimates exclaiming that all comme
In both Swedish political discourse and in Swedish media the phenomenon known as begging is a topical issue. The purpose behind this study was to examine the attitudes and notions toward the phenomenon of begging among social workers within the voluntary and public sector, and also their position on responsibility in relation to this reality. The empirical base of the study was formed by semi-stru
Den här undersökningen föranleddes av en fundering över de humanitära utmaningar världen står inför idag, och vad för typ av insatser som krävs. Uppsatsen undersöker välgörenhetsgalan Tillsammans för Världens Barn. Det teoretiska såväl som metodologiska ramverket är inspirerat av Ernesto Laclau och Chantal Mouffes diskursteori, och med hjälp av den undersöker vi vilka diskurser som genomsyrar gala
En visselblåsare är den person som larmar om fara eller skada för allmänintresset inom ramen för en arbetsrelaterad relation. Personer som vågar blåsa i visslan hyllas ofta av allmänheten för sitt mod och det ligger i både arbetsgivarens, arbetstagarens och samhällets intresse att oegentligheter inom verksamheter kommer fram och kan avhjälpas. I gällande rätt finns inget enhetligt skydd för visselA whistleblower is a person who reports or discloses information on a threat or harm to the public interest in the context of a work-based relationship. Persons who dare to blow the whistle are often times praised by the public for their courage and it is in the best interest of the employer as well as the employee and the society that wrongdoings within organizations are disclosed and eliminated.
This master’s thesis examines the norm-critical awareness among children librarians in Swedish public libraries and how the practical everyday work with current literature for children function with this awareness. By adopting a norm-critical approach you have the ability to observe the different types of norms that you can find among us and that effects the way we see the world. Some of these nor
Flooding and wildfires are two common natural hazards in Sweden to which the Fire and Rescue Services (FRS) must be prepared to respond to. In light of potential increases in these hazards, the Extreme-Index project aims to develop such a multi-hazard tool for Sweden. In this paper, a modular multi-hazard framework is presented. The first module of the multi-hazard methodology that is developed an
Giant cell arteritis (GCA) that affects older patients is an independent risk factor for thromboembolic events. The objective of this study was to identify predictive factors for thromboembolic events in patients with GCA and develop quantitative predictive tools (prognostic nomograms) for pulmonary embolism (PE) and deep venous thrombosis (DVT). A total of 13,029 patients with a GCA diagnosis wer
Bio-based and patient-specific three-dimensional (3D) scaffolds can present next generation strategies for bone tissue engineering (BTE) to treat critical bone size defects. In the present study, a composite filament of poly lactic acid (PLA) and 45S5 bioglass (BG) were used to 3D print scaffolds intended for bone tissue regeneration. The thermally induced phase separation (TIPS) technique was use
