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BACKGROUND AND AIM: The genetic basis of Metabolic syndrome (MetS) is largely unknown but a link with salt sensitivity is recognized. The cytochrome P450 isoform 4F2 (CYP4F2) is involved in renal production of 20-hydroxyeicosatethraenoic acid (20-HETE), a natriuretic substance associated with salt sensitivity. The same enzyme is implicated in ω-hydroxylation of very long and medium chain fatty aci
Objective: To assess whether a genetic risk score that was previously shown to be associated with myocardial infarction and coronary artery disease is also associated with markers of carotid atherosclerosis. Design: A total of 4022 middle-aged subjects from the general Swedish population were genotyped and individually assigned a genetic risk score based on 13 single-nucleotide polymorphisms (SNPs
In clinical genetic diagnostics, it is difficult to predict whether genetic mutations that do not greatly alter the primary sequence of the encoded protein causing unknown functional effects on cognate proteins lead to development of disease. Here, we report the clinical identification of c.2038 T>C missense mutation in exon 18 of the human MLH1 gene and biochemically characterization of the p.Cys
Galiellalactone is a potent and specific inhibitor of STAT3 signaling which has been shown to possess growth inhibitory effects on prostate cancer cells expressing active STAT3. In this study we aimed to investigate the effect of galiellalactone on prostate cancer stem cell-like cells. We explored the expression of aldehyde dehydrogenase (ALDH) as a marker for cancer stem cell-like cells in differ
Angiosarcoma is a rare complication of breast cancer treatment. In order to define predictors, clinical presentation, and outcome, we characterized a population-based 50-year cohort of angiosarcomas after breast cancer. Clinical data were collected from all females with previous breast cancer who developed angiosarcomas/lymphangiosarcomas on the thoracic wall/upper extremity between 1958 and 2008
Having performed analytical validation studies, we are now assessing the clinical utility of the upgraded automated Bone Scan Index (BSI) in metastatic castration-resistant prostate cancer (mCRPC). In the present study, we retrospectively evaluated the discriminatory strength of the automated BSI in predicting overall survival (OS) in mCRPC patients being treated with enzalutamide.
ALF-medel för forskning - Budgetanvisningar 2026 ALF-MEDEL FÖR FORSKNING BUDGETERING AV ÅR 2026 ANVISNINGAR Anvisningarna har utarbetats gemensamt av Medicinska fakulteten och Region Skåne; Medicinska fakulteten, ALF-kansliet och ekonomiavdelningen: Niklas Nielsen, vicedekan Karin Frankel, fakultetsekonom Region Skåne, Avdelningen för hälso- och sjukvårdsstyrning Jesper Petersson, forskningschef C
https://www.intramed.lu.se/sites/intramed.lu.se/files/2025-10/FINAL_Anvisningar%20f%C3%B6r%20ALF%20Budget%202026.pdf - 2026-05-09
Anvisningar för sökande till Masterprogrammet i Fri Konst, 120 hp (Master of Fine Arts) Läsår 2021/2022 Sista ansökningsdag 1 april 2021 V 1.2 Viktiga hålltider och information om ansökan till masterprogrammet i fri konst vid Konsthögskolan i Malmö Ansökan i två steg senast 1 april 2021 1. Generell anmälan på Antagning.se Gå in på Universitets- och högskolerådet webbplats www.antagning.se och följ
https://www.khm.lu.se/sites/khm.lu.se/files/2021-02/mastsve2021.pdf - 2026-05-09
251031_MAA_samlet_25_15_digital.indd A Malmö Art Academy 2024 –2025 Management Maj Hasager Rector Silvana Hed Head of Administration Administration Charlotta Österberg Economy Madeleine Bergquist Librarian Marjaana Kinnunen Programme administrator Amanda Pettersson Communication officer Evalena Tholin Gallery coordinator and administrator Technicians Ariel Alaniz Metal, wood and sculpture workshop
https://www.khm.lu.se/sites/khm.lu.se/files/2025-12/251031_MAA_samlet_25_15_digital_sider_LQ.pdf - 2026-05-09
BioeconomyStakeholderConference_DK_170515.key Deniz Koca, Ph.D., Lund University, Centre for Environmental and Climate Research BIOECONOMY Graduate Research School deniz.koca@cec.lu.se http://www.cec.lu.se/bioeconomy Advancing the Transition to Bioeconomy: A Systems Approach mailto:deniz.koca@cec.lu.se?subject= http://www.cec.lu.se/bioeconomy Layout Background (What is bioeconomy? Do we all have a
https://www.hallbarhet.lu.se/sites/hallbarhet.lu.se/files/bioeconomystakeholderconference_dk_170515_v2.pdf - 2026-05-09
BACKGROUND: Diagnosing heart failure with preserved ejection fraction (HFpEF) remains challenging, particularly in older adults. While the Heart Failure Association (HFA)-PEFF and H2FPEF Scores offer structured diagnostic approaches, their clinical utility is still debated. This study aims to compare the diagnostic accuracy of HFpEF Scores versus inclusion criteria used in sodium-glucose cotranspo
Background: Around 95% of all websites selling medicines globally are illegal and contribute to the spread of substandard and falsified medicines. Hence, it is important to identify legal pharmacies when accessing medicines online. During 2022-2024, 250 million prescriptions were legally dispensed in Sweden, and 69% were prescribed in primary care. Pharmacists and general practitioners are key hea
High-speed vertical In–Ga–As nanowire MOS field-effect transistor (MOSFET) measurements were analyzed through parametric layout models. Measurements from small and large transistors were used to fit dependencies on the number of gate fingers and the number of wires per finger. Extrapolations via intrinsic and parasitic elements reveal the optimal layout for peak frequency performance. To achieve a
Introduction: Ambient air pollution and road traffic noise are stroke risk factors, but evidence on their potential joint effects remains limited. This study investigated the independent and joint associations of air pollution and road traffic noise on stroke incidence using both multiplicative and additive scales. Methods: We followed stroke incidence in ten cohorts in Sweden, Denmark, and Finlan
Aims: Middle Eastern immigrants to western countries are at high risk of developing type 2 diabetes. However, the heritability and impact of first-degree family history (FH) of type 2 diabetes on insulin secretion and action have not been adequately described. Methods: Citizens of Malmö, Sweden, aged 30–75 years born in Iraq or Sweden were invited to participate in this population-based study. Ins
Aims: Testing insulin resistance could help improve physician assessment of patients’ risk of prediabetes or type 2 diabetes (T2D), even among normoglycemic individuals. Methods: The longitudinal study followed 16,333 normoglycemic participants in a nation-wide employer-sponsored health assessment program starting in August 2020 with a median follow-up time of 2.9 years for incident prediabetes or
The transition toward sustainable energy systems has motivated extensive research into scalable routes for solar fuel generation. Silicon-based photoelectrodes are particularly promising due to their favorable optoelectronic properties, abundance, and compatibility with established microfabrication techniques. Nano-microstructuring silicon can enhance photoelectrochemical performance by improving
Several factors contribute to the use, non-use, or inadequate use of personal protective equipment (PPE) in construction work. This study aimed to analyse correct usage of various PPE, such as helmet, ear protectors, goggles, respiratory mask, gloves, protective clothing, and a safety harness. Correct usage was assessed as guessability, which refers to human perceptions of how to don, adjust, use,
ObjectivesTo compare head acceleration between blind football players and non-disabled football players, and between anticipated and unanticipated conditions in blind football players.DesignLaboratory-based exploratory study.MethodsParticipants were ten football players (five blind football, five non-disabled; 80% female). Standardized head perturbations were applied in flexion, extension, lateral
