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Population-based estimates of common comorbidities and cardiovascular disease in ankylosing spondylitis.

OBJECTIVE:: To study the rate of common comorbidities and cardiovascular disease in ankylosing spondylitis (AS) patients compared with the general population seeking health care. METHODS:: This cohort study included 935 subjects (67% men) age ≥20 years, diagnosed with AS and the adult background population in southern Sweden. During 2004 to 2007 we recorded the occurrence of physicians' diagnostic

Male sex and vascular risk factors affect cystatin C-derived renal function in older people without diabetes or overt vascular disease.

Background/objectives: to explore the effect of ageing on renal function with cystatin C as the marker of glomerular filtration rate (GFR) in the general population without vascular disease or diabetes.Design: a cross-sectional analysis of a healthy subset from the Good Aging in Skåne-cohort study representative of the Swedish general population.Subjects: 1252 participants without vascular disease

A 5-Year Exercise Program in Pre- and Peripubertal Children Improves Bone Mass and Bone Size Without Affecting Fracture Risk.

We studied the effect in children of an exercise intervention program on fracture rates and skeletal traits. Fractures were registered for 5 years in a population-based prospective controlled exercise intervention study that included children aged 6-9 years at study start, 446 boys and 362 girls in the intervention group and 807 boys and 780 girls in the control group. Intervention subjects receiv

BPI-ANCA and Long-Term Prognosis among 46 Adult CF Patients: A Prospective 10-Year Follow-Up Study.

Introduction. Anti-neutrophil cytoplasmic antibodies specific for bactericidal/permeability-increasing protein (BPI-ANCA) are frequent in CF patients and mainly develop in response to infection with Pseudomonas aeruginosa. It is not known to what extent BPI-ANCA correlates to prognosis. Objectives. To evaluate the prognostic value of IgA-BPI-ANCA, measured at the beginning of the study, for transp

Elastic and Piezoelectric Properties of Zincblende and Wurtzite Crystalline Nanowire Heterostructures.

The elastic and piezoelectric properties of zincblende and wurtzite crystalline InAs/InP nanowire heterostructures have been studied using electro-elastically coupled continuum elasticity theory. A comprehensive comparison of strains, piezoelectric potentials and piezoelectric fields in the two crystal types of nanowire heterostructures is presented. For each crystal type, three different forms of

Designing pi-stacked molecular structures to control heat transport through molecular junctions

We propose and analyze a way of using pi stacking to design molecular junctions that either enhance or suppress a phononic heat current, but at the same time remain conductors for an electric current. Such functionality is highly desirable in thermoelectric energy converters, as well as in other electronic components where heat dissipation should be minimized or maximized. We suggest a molecular d

The Potential Health Economic Value of Adding Magnetomotive Ultrasound to Current Diagnostic Methods for Detecting Lymph Node Metastases in Rectal Cancer

BACKGROUND: Local resection of early rectal cancer (RC) is a desirable treatment option compared with surgery, offering reduced morbidity, mortality, health care costs and avoidance of stoma. However, local resection is restricted to cases without suspicion of lymph node metastases (LNM). Current methods to diagnose LNM and risk estimations based on histopathology cannot reliably identify patients

Cost-effectiveness of interventions addressing loneliness among adults - A Systematic Literature Review

OBJECTIVES: Loneliness and social isolation are major public health concerns that contribute to numerous health consequences. While many interventions effectively reduce loneliness and social isolation, their cost-effectiveness remain unclear. This study aimed to evaluate and consolidate evidence on the cost-effectiveness of interventions addressing loneliness or social isolation.METHODS: We condu

Risk of recurrence following transanal endoscopic microsurgery without neoadjuvant or adjuvant treatment in T2 rectal cancer

Background: Transanal endoscopic microsurgery (TEM) is only curative treatment for T1 rectal cancer with low-risk features. In T2 cancer, TEM is not recommended but could be used as a palliative procedure and/or in patients unfit for surgery. Few studies exist investigating recurrence after TEM for T2 rectal cancer. Method: Retrospective, population-based study using the Swedish Colorectal Cancer

Packaging impact on consumer experience : voice of the E-customer

With the growth of e-commerce, understanding the nuances of packaging performance and consumer expectations has become essential to enhancing the customer experience. In e-commerce, packaging is a key component of the overall consumer experience, directly influencing perceptions and expectations. Despite its importance, packaging often remains overlooked and is significantly understudied. This exp

Comparison of the C-REX LapAid and Circular Stapled Colorectal Anastomoses in an Experimental Model

The rate of colorectal anastomotic leakage has remained unchanged for the last decades. The limitations of current anastomotic methods have generated an interest in alternative anastomotic techniques, such as compression anastomosis. The aim of this experimental study was to evaluate the early mechanical strength in left colonic anastomoses, comparing C-REX LapAid and circular stapled anastom

Tetrabromobenzene-based molecular alloys - a tool for tailoring the temperature of the thermosalient phase transition

A series of molecular alloys of 1,2,4,5-tetrabromobenzene and 1,2,4,5-tetrachlorobenzene with varying compositions were prepared in an attempt to obtain jumping crystals with adjustable temperature of thermosalient phase transition. Molecular alloys were studied with a combination of thermal and structural techniques (DSC, SCXRD, XRPD, hot-stage microscopy). Alloys with a high 1,2,4,5-tetrabromobe

An Exercise Therapists' Guide to Neuromuscular Exercise for People With Knee or Hip Osteoarthritis

BACKGROUND: Neuromuscular exercise is commonly used in knee injury prevention programs and in rehabilitation following knee injury, and can also be used to address functional impairments is middle-aged and older individuals with knee and hip osteoarthritis (OA). CLINICAL QUESTION: What is neuromuscular exercise for OA? Why should clinicians use it? And how? Nine themes of common questions from exe

Norms in Law and Society: Towards a Definition of the Socio-Legal Concept of Norms

The aim of this paper is to present a model for creating a more coherent concept, designed to meet the demands of the multidisciplinary field of Sociology of Law. This model is built on an ontological analysis that can incorporate different perspectives. The suggested analysis is mainly founded on the Aristotelian concepts of ‘essence’ and ‘accident.’ Thus, the method is concerned with distinguish

Improving the biocatalyst. Engineering of fungal oxidoreductases and thin-film electrodes for improvement of membraneless biofuel cells and carbohydrate biosensors.

This thesis presents investigations for the improvement of electrical contact and catalytical properties of two fungal redox enzymes, cellobiose dehydrogenase (CDH) and pyranose dehydrogenase (PDH), with electrodes and the use of the prepared electrodes as carbohydrate biosensors and in enzymatic biofuel cells. The performance of enzyme modified electrodes can be improved in two ways, by modifying

Utveckling av Byggnadsintegrerade Solenergisystem för Energieffektiva Hus

En solfångarhybrid har utvecklats och utvärderats på avdelningen för Energi och ByggnadsDesign på Lunds Tekniska Högskola, LTH. Solfångarhybriden, ”Solfönstret”, består av solcellslaminerade absorbatorer placerade i ett fönster bakom glasrutorna. Solfönstret finns byggt i ett enfamiljshus, Solgården, i Älvkarleö utanför Gävle. För att minska investeringskostnaderna för solel har reflektorer placerA PV/T collector has been developed and evaluated at the department of Energy and Building Design at the Technical University of Lund, LTH in Sweden. The PV/T, a “solar window” made of PV cells laminated on solar absorbers is placed in a window behind the glazing. The solar window is built into a single family house, Solgården, in Älvkarleö outside Gävle in the eastern part of Sweden. To reduce th

Parental separation in childhood and self-reported psychological health : A population-based study

The aim of the present study is to investigate associations between parental separation/divorce during childhood, and self-reported psychological health, adjusting for social capital, social support, civil status and economic stress in childhood. A cross-sectional public health survey was conducted in the autumn of 2012 in Scania, southern Sweden, with a postal questionnaire with 28,029 participan

The concept of treatment-free remission in chronic myeloid leukemia

The advent of tyrosine kinase inhibitors (TKI) into the management of patients with chronic myeloid leukemia (CML) has profoundly improved prognosis. Survival of responders is approaching that of the general population but lifelong treatment is still recommended. In several trials, TKI treatment has been stopped successfully in approximately half of the patients with deep molecular response. This